Comparing Nitrofurantoin vs Bactrim
Nitrofurantoin | Bactrim |
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Nitrofurantoin | Bactrim (sulfamethoxazole / trimethoprim) |
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Prescription only
Nitrofurantoin is an effective antibiotic with a low risk of inducing bacterial resistance that is used specifically to treat urinary tract infections caused by susceptible bacteria. Long-term use... View more |
Prescription only
Bactrim is an effective combination antibiotic; however, it may not be suitable for those with kidney or liver disease or folate deficiency. The risk of side effects may be higher in the elderly... View more |
Related suggestions Urinary Tract Infection
Prevention of Bladder infection (Cystitis Prophylaxis)
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More about Nitrofurantoin | More about Bactrim (sulfamethoxazole / trimethoprim) | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Nitrofurantoin has an average rating of 4.5 out of 10 from a total of 1857 ratings on Drugs.com. 30% of reviewers reported a positive effect, while 52% reported a negative effect. |
Bactrim has an average rating of 5.5 out of 10 from a total of 614 ratings on Drugs.com. 43% of reviewers reported a positive effect, while 42% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: nitrofurantoin side effects in more detail. |
See also: Bactrim side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all nitrofurantoin prices |
View all Bactrim prices |
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Dosage Forms Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Furadantin, Macrobid, Macrodantin | Other sulfamethoxazole / trimethoprim brands include: Bactrim DS, Bactrim IV, Bactrim Pediatric, Bethaprim, Bethaprim Pediatric, Co-trimoxazole, Septra, Septra DS, SMZ-TMP DS, Sulfatrim Pediatric View more | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
1 hour |
14 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 196 drugs are known to interact with nitrofurantoin:
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A total of 422 drugs are known to interact with Bactrim:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
February 06, 1953 |
July 30, 1973 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.