Comparing Nexium vs Pepcid
| Nexium (esomeprazole) | Pepcid (famotidine) |
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| Nexium (esomeprazole) | Pepcid (famotidine) |
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Prescription only
Nexium is an acid-suppressing agent used to treat conditions associated with excessive stomach acid production, such as gastroesophageal reflux (GERD) and stomach ulcers. Nexium is available orally... View more |
Prescription only
Prescribed for Erosive Esophagitis, Duodenal Ulcer, GERD, Duodenal Ulcer Prophylaxis, Indigestion, Pathological Hypersecretory Conditions, Peptic Ulcer, Stomach Ulcer, Upper GI Hemorrhage... View more |
Related suggestions Erosive Esophagitis
Duodenal Ulcer Prophylaxis
Pathological Hypersecretory Conditions
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| More about Nexium (esomeprazole) | More about Pepcid (famotidine) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Nexium has an average rating of 6.2 out of 10 from a total of 211 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 33% reported a negative effect. |
Pepcid has an average rating of 6.0 out of 10 from a total of 10 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 30% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Nexium side effects |
View all Pepcid side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Lower cost generic approved | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Nexium prices |
View all Pepcid prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other esomeprazole brands include: Nexium 24HR, Nexium IV | Other famotidine brands include: Acid Control, Acid Controller Maximum Strength, Acid Controller Original Strength, Acid Reducer Maximum Strength, Acid Reducer Original Strength, Acid Reducer-Famotidine, Heartburn Relief, Heartburn Relief Maximum Strength, Pepcid AC, Pepcid AC Chewable Tablets, Pepcid AC Maximum Strength, Pepcid AC Maximum Strength Tablets, Pepcid Oral Suspension, Zantac 360 View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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1.5 hours |
4 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 214 drugs are known to interact with Nexium:
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A total of 312 drugs are known to interact with Pepcid:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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N/A |
October 15, 1986 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.