Intrarosa Alternatives Compared
| Intrarosa (dehydroepiandrosterone) | Osphena (ospemifene) | Estradiol topical |
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| Intrarosa (dehydroepiandrosterone) | Osphena (ospemifene) | Estradiol topical |
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Prescription and OTC
Prescribed for Dyspareunia. Intrarosa may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Vaginal Dryness, Atrophic Vaginitis, Dyspareunia, Postmenopausal Symptoms, Perimenopausal Symptoms. Osphena may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis, Dyspareunia, Overactive Bladder. Estradiol topical may also be used for purposes not listed in this medication guide. |
Related suggestions Dyspareunia
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| More about Intrarosa (dehydroepiandrosterone) | More about Osphena (ospemifene) | More about Estradiol topical | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Intrarosa has an average rating of 5.4 out of 10 from a total of 111 ratings on Drugs.com. 41% of reviewers reported a positive effect, while 41% reported a negative effect. |
Osphena has an average rating of 5.3 out of 10 from a total of 45 ratings on Drugs.com. 36% of reviewers reported a positive effect, while 40% reported a negative effect. |
Estradiol topical has an average rating of 5.1 out of 10 from a total of 487 ratings on Drugs.com. 37% of reviewers reported a positive effect, while 45% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Intrarosa side effects |
View all Osphena side effects |
View all Estradiol topical side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Intrarosa prices |
View all Osphena prices |
View all Estradiol topical prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Other dehydroepiandrosterone brands include: DHEA |
N/A |
Estrace Vaginal Cream, Estring, Imvexxy, Vagifem, Yuvafem | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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N/A |
26 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 182 drugs are known to interact with Intrarosa:
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A total of 97 drugs are known to interact with Osphena:
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A total of 237 drugs are known to interact with Estradiol topical:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
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| First Approval Date | ||||||||||||||||||||||||||
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November 16, 2016 |
February 26, 2013 |
January 31, 1984 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient Resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.