Comparing Indomethacin vs Naproxen
Indomethacin | Naproxen |
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Indomethacin | Naproxen |
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Prescription only
Indomethacin relieves inflammation and pain associated with various types of arthritis. The risk of stomach-related and cardiovascular side effects may be higher with indomethacin than that seen... View more |
Prescription and OTC
Naproxen is effective for the short-term relief of pain and inflammation associated with arthritis, gout, menstruation, and tendonitis; however, like other NSAIDs, it has the potential to adversely... View more |
Related suggestions Osteoarthritis
Rheumatoid Arthritis
Popular comparisons
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More about Indomethacin | More about Naproxen | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Indomethacin has an average rating of 7.8 out of 10 from a total of 210 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 14% reported a negative effect. |
Naproxen has an average rating of 6.8 out of 10 from a total of 683 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 25% reported a negative effect. |
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Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Indomethacin side effects |
View all Naproxen side effects |
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Drug Class | |||||||||||||||||
Generic Availability | |||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Indomethacin prices |
View all Naproxen prices |
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Dosage Forms | |||||||||||||||||
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Brand Names | |||||||||||||||||
Indocin, Indocin IV, Indocin SR, Tivorbex | Aflaxen, Aleve, Aleve Back and Muscle Pain, All Day Pain Relief, All Day Relief, Anaprox-DS, Comfort Pac with Naproxen, EC-Naprosyn, Flanax Pain Reliever, Midol Extended Relief, Naprelan, Naprosyn, Naproxen Sodium DS, Pamprin All Day Relief View more | ||||||||||||||||
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
4.5 hours |
18 hours |
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CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category C
Risk cannot be ruled out
Prior To 30 Weeks Gestation
Category D
Positive evidence of risk
Starting At 30 Weeks Gestation See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 418 drugs are known to interact with Indomethacin:
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A total of 451 drugs are known to interact with Naproxen:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
June 10, 1965 |
March 11, 1976 |
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WADA Class View classifications | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient Resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.