Indomethacin Alternatives Compared
| Indomethacin | Xeljanz (tofacitinib) | Humira (adalimumab) |
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| Indomethacin | Xeljanz (tofacitinib) | Humira (adalimumab) |
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Prescription only
Indomethacin relieves inflammation and pain associated with various types of arthritis. The risk of stomach-related and cardiovascular side effects may be higher with indomethacin than that seen... View more |
Prescription only
Xeljanz is a Janus kinase (JAK) inhibitor that may be used to reduce inflammation associated with several conditions such as rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, or... View more |
Prescription only
Humira is a TNF-alfa inhibitor that may be used to treat a wide range of different inflammatory conditions, such as Rheumatoid Arthritis, psoriasis, ankylosing spondylitis, Crohn's disease, and... View more |
Related suggestions Rheumatoid Arthritis
Ankylosing Spondylitis
Popular comparisons
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| More about Indomethacin | More about Xeljanz (tofacitinib) | More about Humira (adalimumab) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Indomethacin has an average rating of 7.8 out of 10 from a total of 210 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 14% reported a negative effect. |
Xeljanz has an average rating of 5.7 out of 10 from a total of 145 ratings on Drugs.com. 43% of reviewers reported a positive effect, while 40% reported a negative effect. |
Humira has an average rating of 6.4 out of 10 from a total of 698 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 31% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Indomethacin side effects |
View all Xeljanz side effects |
View all Humira side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
N/A |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Indomethacin prices |
View all Xeljanz prices |
View all Humira prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Indocin, Indocin IV, Indocin SR, Tivorbex | Other tofacitinib brands include: Xeljanz Oral Solution, Xeljanz XR | Other adalimumab brands include: Abrilada, Amjevita, Cyltezo, Hadlima, Hulio, Hyrimoz, Idacio, Simlandi, Yuflyma, Yusimry View more | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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4.5 hours |
3 hours |
480 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
Prior To 30 Weeks Gestation
Category D
Positive evidence of risk
Starting At 30 Weeks Gestation See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 418 drugs are known to interact with Indomethacin:
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A total of 655 drugs are known to interact with Xeljanz:
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A total of 550 drugs are known to interact with Humira:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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June 10, 1965 |
November 06, 2012 |
December 31, 2002 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.