Comparing Fluconazole vs Ketoconazole
| Fluconazole | Ketoconazole |
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| Fluconazole | Ketoconazole |
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Prescription only
Fluconazole is an effective antifungal agent that may be used to treat certain fungal or yeast infections. Side effects include headache, nausea, abdominal pain, diarrhea, indigestion, and... View more |
Prescription only
Prescribed for Chronic Mucocutaneous Candidiasis, Coccidioidomycosis, Blastomycosis, Paracoccidioidomycosis, Chromomycosis, Histoplasmosis, Dermatophytosis, Esophageal Candidiasis, Onychomycosis -... View more |
Related suggestions Vaginal Yeast Infection
Onychomycosis, Toenail
Tinea Versicolor
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| More about Fluconazole | More about Ketoconazole | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Fluconazole has an average rating of 6.3 out of 10 from a total of 530 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 30% reported a negative effect. |
Ketoconazole has an average rating of 6.6 out of 10 from a total of 24 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 29% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Fluconazole side effects |
View all Ketoconazole side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Fluconazole prices |
View all Ketoconazole prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Diflucan |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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50 hours |
4.6 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
Single 150 Mg Tablet Use For Vaginal Candidiasis
Category D
Positive evidence of risk
All Indications (excluding Single 150 Mg Tablet Use For Vaginal Candidiasis) See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 573 drugs are known to interact with Fluconazole:
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A total of 851 drugs are known to interact with Ketoconazole:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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January 29, 1990 |
June 12, 1981 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.