Estradiol Alternatives Compared
| Estradiol | Premarin (conjugated estrogens) | Estradiol Patch (estradiol) |
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| Estradiol | Premarin (conjugated estrogens) | Estradiol Patch (estradiol) |
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Prescription only
Estradiol is a synthetic form of estrogen that may be given for several different indications, including the relief of menopausal symptoms or low estrogen levels caused by other conditions. Its use... View more |
Prescription only
Prescribed for Atrophic Vaginitis, Abnormal Uterine Bleeding, Atrophic Urethritis, Breast Cancer - Palliative, Hypoestrogenism, Oophorectomy, Osteoporosis, Postmenopausal Symptoms, Primary Ovarian... View more |
Prescription only
Prescribed for Atrophic Vaginitis, Postmenopausal Symptoms, Atrophic Urethritis, Oophorectomy, Hypoestrogenism, Breast Cancer - Palliative, Primary Ovarian Failure, Prevention of Osteoporosis... View more |
Related suggestions Postmenopausal Symptoms
Atrophic Vaginitis
Prostate Cancer
Oophorectomy
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| More about Estradiol | More about Premarin (conjugated estrogens) | More about Estradiol Patch (estradiol) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Estradiol has an average rating of 5.8 out of 10 from a total of 587 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 37% reported a negative effect. |
Premarin has an average rating of 7.7 out of 10 from a total of 84 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 17% reported a negative effect. |
Estradiol Patch has an average rating of 4.6 out of 10 from a total of 168 ratings on Drugs.com. 35% of reviewers reported a positive effect, while 54% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Estradiol side effects |
View all Premarin side effects |
View all Estradiol Patch side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
Lower cost generic approved | |||||||||||||||||||||||||
| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Estradiol prices |
View all Premarin prices |
View all Estradiol Patch prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Alora, Climara, Delestrogen, Depo-Estradiol, Divigel, Dotti, Elestrin, Estra Pellets, Estrace, Estraderm, Estradiol Patch, Estrogel, Evamist, Femring, Lyllana, Menostar, Minivelle, Vivelle-Dot View more | Other conjugated estrogens brands include: Premarin Intravenous | Other estradiol brands include: Alora, Climara, Delestrogen, Depo-Estradiol, Divigel, Dotti, Elestrin, Estra Pellets, Estrace, Estraderm, Estrogel, Evamist, Femring, Lyllana, Menostar, Minivelle, Vivelle-Dot View more | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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16 hours |
N/A |
16 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 369 drugs are known to interact with Estradiol:
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A total of 250 drugs are known to interact with Premarin:
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A total of 369 drugs are known to interact with Estradiol Patch:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
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| First Approval Date | ||||||||||||||||||||||||||
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July 23, 1975 |
May 08, 1942 |
N/A |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient Resources | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.