Comparing Effexor XR vs Trintellix
| Effexor XR (venlafaxine) | Trintellix (vortioxetine) |
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| Effexor XR (venlafaxine) | Trintellix (vortioxetine) |
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Prescription only
Prescribed for Autism, Major Depressive Disorder, Depression, Generalized Anxiety Disorder, Anxiety, Postpartum Depression, Panic Disorder, Social Anxiety Disorder, Vulvodynia. Effexor XR may also be... View more |
Prescription only
Trintellix may be used to treat depression in adults. It is different from other antidepressants currently on the market because it directly affects serotonin receptors as well as inhibits serotonin... View more |
Related suggestions |
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| More about Effexor XR (venlafaxine) | More about Trintellix (vortioxetine) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Effexor XR has an average rating of 6.9 out of 10 from a total of 1012 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 23% reported a negative effect. |
Trintellix has an average rating of 6.0 out of 10 from a total of 1129 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 32% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Effexor XR side effects |
View all Trintellix side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Effexor XR prices |
View all Trintellix prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other venlafaxine brands include: Effexor |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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4 hours |
66 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 701 drugs are known to interact with Effexor XR:
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A total of 354 drugs are known to interact with Trintellix:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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October 20, 1997 |
September 30, 2013 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.