Comparing Cymbalta vs Effexor XR
| Cymbalta (duloxetine) | Effexor XR (venlafaxine) |
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| Cymbalta (duloxetine) | Effexor XR (venlafaxine) |
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Prescription only
Cymbalta has antidepressant, anti-anxiety, and pain-relieving properties; however, it has been associated with a discontinuation syndrome on withdrawal even when tapered. Prescribed for Back Pain... View more |
Prescription only
Prescribed for Autism, Major Depressive Disorder, Depression, Generalized Anxiety Disorder, Anxiety, Postpartum Depression, Panic Disorder, Social Anxiety Disorder, Vulvodynia. Effexor XR may also be... View more |
Related suggestions Depression
Major Depressive Disorder
Generalized Anxiety Disorder
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| More about Cymbalta (duloxetine) | More about Effexor XR (venlafaxine) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Cymbalta has an average rating of 6.3 out of 10 from a total of 1900 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 30% reported a negative effect. |
Effexor XR has an average rating of 6.9 out of 10 from a total of 1012 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 23% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Cymbalta side effects |
View all Effexor XR side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Cymbalta prices |
View all Effexor XR prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other duloxetine brands include: Drizalma Sprinkle, Irenka | Other venlafaxine brands include: Effexor | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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17 hours |
4 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 624 drugs are known to interact with Cymbalta:
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A total of 700 drugs are known to interact with Effexor XR:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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N/A |
October 20, 1997 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.