Cymbalta Interactions
There are 624 drugs known to interact with Cymbalta (duloxetine), along with 10 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 109 are major, 492 are moderate, and 23 are minor.
- View all 624 medications that may interact with Cymbalta
- View Cymbalta alcohol/food interactions (2)
- View Cymbalta disease interactions (10)
Most frequently checked interactions
View interaction reports for Cymbalta (duloxetine) and the medicines listed below.
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- amlodipine
- aspirin
- atorvastatin
- baclofen
- clonazepam
- cyclobenzaprine
- Flexeril (cyclobenzaprine)
- gabapentin
- ibuprofen
- Klonopin (clonazepam)
- Lamictal (lamotrigine)
- levothyroxine
- lisinopril
- Lyrica (pregabalin)
- metformin
- omeprazole
- oxycodone
- pantoprazole
- prednisone
- Singulair (montelukast)
- Synthroid (levothyroxine)
- tizanidine
- tramadol
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zyrtec (cetirizine)
Cymbalta alcohol/food interactions
There are 2 alcohol/food interactions with Cymbalta (duloxetine).
Cymbalta disease interactions
There are 10 disease interactions with Cymbalta (duloxetine) which include:
- liver disease
- renal disease
- depression
- diabetes
- glaucoma
- hypertension
- hyponatremia
- mania
- seizures
- urinary tract obstruction
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More about Cymbalta (duloxetine)
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- Drug class: serotonin-norepinephrine reuptake inhibitors
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
