Comparing Dextroamphetamine vs Methylphenidate
| Dextroamphetamine | Methylphenidate |
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| Dextroamphetamine | Methylphenidate |
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Prescription only
Prescribed for ADHD, Sexual Dysfunction - SSRI Induced, Narcolepsy, Fatigue, Drowsiness. Dextroamphetamine may also be used for purposes not listed in this medication guide. |
Prescription only
Methylphenidate can help improve symptoms of ADHD but may cause dependence and side effects include a headache, loss of appetite, and sleeplessness. It is recommended that methylphenidate should not... View more |
Related suggestions ADHD (Attention Deficit Hyperactivity Disorder)
Popular comparisons
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| More about Dextroamphetamine | More about Methylphenidate | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Dextroamphetamine has an average rating of 8.3 out of 10 from a total of 292 ratings on Drugs.com. 80% of reviewers reported a positive effect, while 10% reported a negative effect. |
Methylphenidate has an average rating of 7.2 out of 10 from a total of 1072 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 17% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Dextroamphetamine prices |
View all Methylphenidate prices |
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| Dosage Forms Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Dexedrine, ProCentra, Xelstrym, Zenzedi | Aptensio XR, Concerta, Cotempla XR-ODT, Daytrana, Jornay PM, Metadate CD, Methylin, Methylin ER, QuilliChew ER, Quillivant XR, Relexxii, Ritalin, Ritalin LA View more | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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34 hours |
4 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 204 drugs are known to interact with Dextroamphetamine:
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A total of 198 drugs are known to interact with Methylphenidate:
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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May 29, 1975 |
December 05, 1955 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
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| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.