Comparing Cymbalta vs Trazodone
Cymbalta | Trazodone |
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Cymbalta (duloxetine) | Trazodone |
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Prescription only
Cymbalta has antidepressant, anti-anxiety, and pain-relieving properties; however, it has been associated with a discontinuation syndrome on withdrawal even when tapered. Prescribed for Back Pain... View more |
Prescription only
Trazodone is mostly used for its sleep-inducing effects (an off-label indication) rather than as an antidepressant. Only generic forms are available which makes it a lot cheaper than some other... View more |
Related suggestions Depression
Major Depressive Disorder
Fibromyalgia
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More about Cymbalta (duloxetine) | More about Trazodone | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Cymbalta has an average rating of 6.3 out of 10 from a total of 1876 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 30% reported a negative effect. |
Trazodone has an average rating of 6.3 out of 10 from a total of 1404 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 31% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: Cymbalta side effects in more detail. |
See also: trazodone side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Cymbalta prices |
View all trazodone prices |
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Dosage Forms Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Other duloxetine brands include: Drizalma Sprinkle, Irenka |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
17 hours |
7.5 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 593 drugs are known to interact with Cymbalta:
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A total of 648 drugs are known to interact with trazodone:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
N/A |
December 24, 1981 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.