Skip to main content

Cotempla XR-ODT Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Cotempla XR-ODT (methylphenidate) Adderall (amphetamine / dextroamphetamine) Vyvanse (lisdexamfetamine)
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Cotempla XR-ODT (methylphenidate) Adderall (amphetamine / dextroamphetamine) Vyvanse (lisdexamfetamine)
Prescription only

Prescribed for ADHD. Cotempla XR-ODT may also be used for purposes not listed in this medication guide.

Prescription only

Adderall is a combination of four different amphetamine salts and may be used to improve attention, focus, or reduce impulsive behaviors in children over the age of 3 and adults with ADHD. It can... View more

Prescription only

Vyvanse is a stimulant used for the treatment of ADHD to reduce symptoms such as impulsiveness and hyperactivity and to increase attention. It can also help increase the number of binge-free days per... View more

Related suggestions
More about Cotempla XR-ODT (methylphenidate) More about Adderall (amphetamine / dextroamphetamine) More about Vyvanse (lisdexamfetamine)
Ratings & Reviews

Cotempla XR-ODT has an average rating of 6.5 out of 10 from a total of 8 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 25% reported a negative effect.

Adderall has an average rating of 7.4 out of 10 from a total of 505 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 17% reported a negative effect.

Vyvanse has an average rating of 7.4 out of 10 from a total of 972 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 15% reported a negative effect.

View all 8 reviews

View all 505 reviews

View all 972 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Cotempla XR-ODT side effects

View all Adderall side effects

View all Vyvanse side effects
Drug Class
Generic Availability

No lower cost generic approved

Lower cost generic approved

Lower cost generic approved
Pricing and Coupons * Prices are without insurance
Quantity 30 each
Strength 8.6 mg/24 hr
Per unit* $18.71
Cost* $561.15

View all Cotempla XR-ODT prices

Quantity 100 tablet
Strength 5 mg
Per unit* $12.34
Cost* $1,233.97

View all Adderall prices

Quantity 100 capsule
Strength 30 mg
Per unit* $13.59
Cost* $1,358.73

View all Vyvanse prices

Get free Discount Card

Get free Discount Card

Get free Discount Card

Dosage Forms
  • Oral tablet, disintegrating, extended release
  • Oral tablet
  • Oral capsule
  • Oral tablet, chewable
Brand Names
Other methylphenidate brands include: Aptensio XR, Concerta, Daytrana, Jornay PM, Metadate CD, Methylin, Methylin ER, QuilliChew ER, Quillivant XR, Relexxii, Ritalin, Ritalin LA View more Other amphetamine / dextroamphetamine brands include: Adderall XR, Mydayis

N/A
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

4 hours

14 hours

1 hour
CSA Schedule 1 View glossary of CSA terms
2
High potential for abuse

Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
2
High potential for abuse

Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
2
High potential for abuse

Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
Pregnancy Category
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.
Drug Interactions

A total of 206 drugs are known to interact with Cotempla XR-ODT:

  • 22 major drug interactions (98 brand and generic names)
  • 173 moderate drug interactions (730 brand and generic names)
  • 11 minor drug interactions (33 brand and generic names)

A total of 220 drugs are known to interact with Adderall:

  • 38 major drug interactions (135 brand and generic names)
  • 174 moderate drug interactions (939 brand and generic names)
  • 8 minor drug interactions (28 brand and generic names)

A total of 392 drugs are known to interact with Vyvanse:

  • 100 major drug interactions (303 brand and generic names)
  • 283 moderate drug interactions (1395 brand and generic names)
  • 9 minor drug interactions (27 brand and generic names)
Alcohol/Food/Lifestyle Interactions
  • Do not use alcohol or medications that contain alcohol while you are receiving treatment with... View more
  • Using amphetamine together with alcohol can increase the risk of cardiovascular side effects such... View more
  • Using lisdexamfetamine together with alcohol can increase the risk of cardiovascular side effects... View more
Disease Interactions
First Approval Date

June 19, 2017

January 19, 1960

February 23, 2007
WADA Class View classifications

N/A
More Information
Patient Resources
Professional Resources
Related Treatment Guide

1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Compare Drugs

To view a report comparing 3 (or more) medications, please sign in or create an account.

Create an account Sign In