Comparing Codeine vs Morphine
| Codeine | Morphine |
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| Codeine | Morphine |
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Prescription only
Codeine is an effective pain reliever; however, it is addictive, may cause constipation, and its pain-relieving effects vary markedly between individuals. Codeine should only be used for pain relief... View more |
Prescription only
Morphine is a very effective pain reliever but commonly causes constipation and carries a high risk of addiction and dependence. It interacts with several other medications, which can increase the... View more |
Related suggestions Popular comparisons
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| More about Codeine | More about Morphine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Codeine has an average rating of 8.0 out of 10 from a total of 68 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 13% reported a negative effect. |
Morphine has an average rating of 7.5 out of 10 from a total of 364 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 13% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Codeine prices |
View all Morphine prices |
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| Dosage Forms Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Astramorph PF, Doloral, Doloral Sirop, Duramorph, Duramorph PF, Infumorph, Kadian, M O S, Mitigo, Morphine Sulfate ER, Morphine Sulfate IR, Morphine Sulfate SR, MS Contin View more | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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3.5 hours |
4 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 508 drugs are known to interact with Codeine:
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A total of 542 drugs are known to interact with Morphine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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July 16, 2009 |
May 29, 1987 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.