Comparing Codeine vs Morphine
| Codeine | Morphine |
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| Codeine | Morphine |
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Prescription only
Codeine is used to relieve mild-to-moderate pain where treatment with an opioid is appropriate. However, it is addictive, may cause constipation and drowsiness, and its pain-relieving effects vary... View more |
Prescription only
Morphine is a very effective pain reliever but commonly causes constipation and carries a high risk of addiction and dependence. It interacts with several other medications, which can increase the... View more |
Related suggestions Popular comparisons
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| More about Codeine | More about Morphine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Codeine has an average rating of 7.8 out of 10 from a total of 70 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 16% reported a negative effect. |
Morphine has an average rating of 7.5 out of 10 from a total of 366 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 14% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Codeine side effects |
View all Morphine side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Codeine prices |
View all Morphine prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Astramorph PF, Doloral, Doloral Sirop, Duramorph, Duramorph PF, Infumorph, Kadian, M O S, Mitigo, Morphine Sulfate ER, Morphine Sulfate IR, Morphine Sulfate SR, MS Contin View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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3.5 hours |
4 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 524 drugs are known to interact with Codeine:
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A total of 565 drugs are known to interact with Morphine:
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| First Approval Date | |||||||||||||||||
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July 16, 2009 |
May 29, 1987 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.