Comparing Co-trimoxazole vs Metronidazole
| Co-trimoxazole (sulfamethoxazole / trimethoprim) | Metronidazole |
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| Co-trimoxazole (sulfamethoxazole / trimethoprim) | Metronidazole |
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Prescription only
Prescribed for Bacterial Skin Infection, Bacterial Infection, Diverticulitis, Bronchitis, Epiglottitis, Granuloma Inguinale, Infection Prophylaxis, Kidney Infections, Melioidosis, Meningitis, Middle... View more |
Prescription only
Metronidazole is an antibiotic that is particularly effective at treating infections caused by susceptible anaerobic bacteria and parasites. Alcohol and products containing propylene glycol should... View more |
Related suggestions Bacterial Infection
Diverticulitis
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| More about Co-trimoxazole (sulfamethoxazole / trimethoprim) | More about Metronidazole | ||||||||
| Ratings & Reviews | |||||||||
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Co-trimoxazole has an average rating of 7.0 out of 10 from a total of 4 ratings on Drugs.com. 75% of reviewers reported a positive effect, while 25% reported a negative effect. |
Metronidazole has an average rating of 6.0 out of 10 from a total of 2431 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 29% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
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View all Co-trimoxazole side effects |
View all Metronidazole side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
| Lower cost generic approved |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Metronidazole prices |
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| Dosage Forms | |||||||||
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N/A |
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| Brand Names | |||||||||
| Other sulfamethoxazole / trimethoprim brands include: Bactrim, Bactrim DS, Bactrim IV, Bactrim Pediatric, Bethaprim, Bethaprim Pediatric, Septra, Septra DS, SMZ-TMP DS, Sulfatrim Pediatric View more | Flagyl, Flagyl 375, Flagyl IV, Likmez, Metro, Metro IV | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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14 hours |
20 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 450 drugs are known to interact with Co-trimoxazole:
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A total of 378 drugs are known to interact with Metronidazole:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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N/A |
July 18, 1963 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.