Calamine topical Alternatives Compared
| Calamine topical | Hydroxyzine | Benadryl (diphenhydramine) |
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| Calamine topical | Hydroxyzine | Benadryl (diphenhydramine) |
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Over-the-counter
Prescribed for Pruritus. Calamine topical may also be used for purposes not listed in this medication guide. |
Prescription only
Hydroxyzine may be used to relieve anxiety or itching; however, it causes sedation so can affect a person's ability to drive or operate machinery. It should not be used during pregnancy or while... View more |
Prescription and OTC
Benadryl is an antihistamine that can be used to treat allergic reactions, relieve motion sickness, as a sleep aid, and relieve some symptoms of Parkinson's disease. Sedation is a common side effect... View more |
Related suggestions |
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| More about Calamine topical | More about Hydroxyzine | More about Benadryl (diphenhydramine) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Calamine topical has an average rating of 9.3 out of 10 from a total of 4 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
Hydroxyzine has an average rating of 5.8 out of 10 from a total of 1392 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 35% reported a negative effect. |
Benadryl has an average rating of 7.2 out of 10 from a total of 78 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Side Effects | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
Lower cost generic |
N/A |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Calamine topical prices |
View all Hydroxyzine prices |
View all Benadryl prices |
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| Dosage Forms Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Calamine Plain | Vistaril | Other diphenhydramine brands include: Aler-Dryl, Aler-Tab, Aller-G-Time, Allergia-C, Allermax, Altaryl, Aurodryl Children's Allergy, Banaril, Banophen, Beldin, Belix, Ben-Tann, Benadryl Allergy, Benadryl Children's Allergy, Benahist-10, Benahist-50, Benoject-50, Buckley's Bedtime, Bydramine, Calm-Aid, Complete Allergy Relief, Compoz Nighttime Sleep Aid, ConRx Allergy, Dicopanol, Diphedryl, Diphen, Diphen AF, Diphen Cough, Diphenadryl, Diphendryl, Diphenhist, Diphenmax, Diphenydramine Quick Melt, Diphenyl, Diphenylin, Dormin, DPH, Dytan, Dytuss, Genahist, Help I Can't Sleep, Histaprin, Hydramine, Hydramine Compound, Hydramine Cough Syrup, Hyrexin, Miles Nervine, Nytol, Nytol Caplet, Nytol QuickCaps, Pharbedryl, Scot-Tussin Allergy, Siladryl Allergy, Silphen Cough, Simply Sleep, Sleep Tab II, Sleep-ettes D, Sleepinal, Sleepwell 2-nite, Snooze Fast, Sominex, Sominex Maximum Strength Caplet, Trux-adryl, Twilite, Unisom Liquid, Unisom SleepGels, Unisom SleepMelts, Unisom SleepMinis, Valu-Dryl, Vanamine PD, Vicks QlearQuil Nighttime Allergy Relief, Z-Sleep, ZzzQuil View more | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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N/A |
7 hours |
9.3 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category N
Not classified
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Category N
Not classified
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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No known drug interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
A total of 584 drugs are known to interact with Hydroxyzine:
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A total of 451 drugs are known to interact with Benadryl:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | ||||||||||||||||||||||||||
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N/A |
April 12, 1956 |
March 04, 1946 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
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N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.