Comparing Buprenorphine vs Naloxone
| Buprenorphine | Naloxone |
|
|---|
| Buprenorphine | Naloxone |
|
|||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Prescription only
Buprenorphine is a potent analgesic that should be only used to treat moderate to severe pain or for the treatment of opioid addiction under strict conditions. Different formulations of the drug... View more |
Prescription and OTC
Naloxone can be used by consumers and the lay-public, first-responders and healthcare providers to help reverse an overdose due to opioids (narcotics), including heroin and prescription opioids. It... View more |
||||||||||||||||
| More about Buprenorphine | More about Naloxone | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
|
Buprenorphine has an average rating of 6.7 out of 10 from a total of 1147 ratings on Drugs.com. 57% of reviewers reported a positive effect, while 25% reported a negative effect. |
Naloxone has an average rating of 7.7 out of 10 from a total of 27 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 22% reported a negative effect. |
||||||||||||||||
| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Buprenorphine side effects |
View all Naloxone side effects |
||||||||||||||||
| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
|
Lower cost generic |
Lower cost generic |
||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Buprenorphine prices |
View all Naloxone prices |
||||||||||||||||
| Dosage Forms | |||||||||||||||||
|
|
||||||||||||||||
| Brand Names | |||||||||||||||||
| Belbuca, Brixadi, Buprenex, Butrans, Sublocade | Kloxxado, Narcan, Rextovy, Rezenopy, RiVive, Zimhi | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
|
48 hours |
3 hours |
||||||||||||||||
| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
|
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
||||||||||||||||
| Pregnancy Category | |||||||||||||||||
|
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
||||||||||||||||
| Drug Interactions | |||||||||||||||||
|
A total of 716 drugs are known to interact with Buprenorphine:
|
A total of 30 drugs are known to interact with Naloxone:
|
||||||||||||||||
| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
|
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
||||||||||||||||
| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
|
December 29, 1981 |
April 13, 1971 |
||||||||||||||||
| WADA Class View classifications | |||||||||||||||||
|
N/A |
|||||||||||||||||
| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.