Buprenorphine Interactions
There are 693 drugs known to interact with buprenorphine, along with 12 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 206 are major, 483 are moderate, and 4 are minor.
- View all 693 medications that may interact with buprenorphine
- View buprenorphine alcohol/food interactions (1)
- View buprenorphine disease interactions (12)
Most frequently checked interactions
View interaction reports for buprenorphine and the medicines listed below.
- Acetylsalicylic Acid (aspirin)
- Adderall (amphetamine / dextroamphetamine)
- Benadryl (diphenhydramine)
- Celebrex (celecoxib)
- Combivent (albuterol / ipratropium)
- Cymbalta (duloxetine)
- Eliquis (apixaban)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- Klonopin (clonazepam)
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Tartrate (metoprolol)
- Norco (acetaminophen / hydrocodone)
- Ozempic (semaglutide)
- Paracetamol (acetaminophen)
- Prozac (fluoxetine)
- Seroquel (quetiapine)
- Synthroid (levothyroxine)
- Tylenol (acetaminophen)
- Valium (diazepam)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Xanax (alprazolam)
- Zofran (ondansetron)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Buprenorphine alcohol/food interactions
There is 1 alcohol/food interaction with buprenorphine.
Buprenorphine disease interactions
There are 12 disease interactions with buprenorphine which include:
- drug dependence
- respiratory depression
- gastrointestinal obstruction
- intracranial pressure
- adrenal insufficiency
- hypotension
- liver disease
- QT prolongation
- renal dysfunction
- urinary retention
- seizure disorders
- biliary tract disease
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More about buprenorphine
- buprenorphine consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (1,128)
- Drug images
- Latest FDA alerts (5)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: Opioids (narcotic analgesics)
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
