Comparing Baricitinib vs Upadacitinib

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Baricitinib	Upadacitinib	Enter another drug to compare

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Baricitinib	Upadacitinib	Enter another drug to compare
Prescription only Prescribed for Alopecia, Rheumatoid Arthritis, COVID-19. Baricitinib may also be used for purposes not listed in this medication guide.	Prescription only Prescribed for Crohn's Disease, Ankylosing Spondylitis, Atopic Dermatitis, Non-Radiographic Axial Spondyloarthritis, Polyarticular Juvenile Idiopathic Arthritis, Psoriatic Arthritis, Rheumatoid... View more	Related suggestions Rheumatoid Arthritis Methotrexate Humira Hydroxychloroquine Prednisone Meloxicam Celebrex
More about Baricitinib	More about Upadacitinib
Ratings & Reviews
Baricitinib has an average rating of 8.3 out of 10 from a total of 16 ratings on Drugs.com. 88% of reviewers reported a positive effect, while 13% reported a negative effect.	Upadacitinib has an average rating of 7.0 out of 10 from a total of 231 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 18% reported a negative effect.
View all 16 reviews	View all 231 reviews
Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.
View all Baricitinib side effects	Acne (9.5%) Dizziness (7.4%) Nausea (7.4%) Fatigue (6.5%) Headaches (5.6%) Swelling (5.6%) Tiredness (5.2%) View all Upadacitinib side effects
Drug Class
Antirheumatics Selective immunosuppressants	Antirheumatics
Generic Availability
N/A	N/A
Pricing and Coupons * Prices are without insurance
We could not find an exact match for this medicine. Try searching the Price Guide directly.	We could not find an exact match for this medicine. Try searching the Price Guide directly.
Get free Discount Card	Get free Discount Card

Dosage Forms
Oral tablet	N/A
Brand Names
Olumiant	Rinvoq, Rinvoq LQ
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.
12.5 hours	14 hours
CSA Schedule ¹ View glossary of CSA terms
N Not a controlled drug Is not subject to the Controlled Substances Act.	N Not a controlled drug Is not subject to the Controlled Substances Act.
Pregnancy Category
Summary unavailable. See the full pregnancy warnings document.	Summary unavailable. See the full pregnancy warnings document.
Drug Interactions
A total of 508 drugs are known to interact with Baricitinib: 343 major drug interactions (1154 brand and generic names) 155 moderate drug interactions (659 brand and generic names) 10 minor drug interactions (39 brand and generic names)	A total of 596 drugs are known to interact with Upadacitinib: 380 major drug interactions (1251 brand and generic names) 206 moderate drug interactions (844 brand and generic names) 10 minor drug interactions (40 brand and generic names)
Alcohol/Food/Lifestyle Interactions
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.	Consumption of grapefruit, grapefruit juice, and supplements that contain grapefruit should be... View more
Disease Interactions
Infections Tuberculosis Cardiovascular risk Malignancy Thrombosis GI perforation Hepatic impairment Laboratory abnormalities Renal dysfunction Viral hepatitis	Cardiovascular risk Malignancy Thrombosis Infections Cytopenias Gastrointestinal perforation Hepatic impairment Hyperlipidemia Vaccination
First Approval Date
N/A	August 16, 2019
WADA Class View classifications
N/A	N/A
More Information
Side effects Drug interactions Dosage Pregnancy warnings Breastfeeding warnings Support group En español	Side effects Drug interactions Dosage Pregnancy warnings Breastfeeding warnings Support group En español
Patient Resources
Baricitinib uses	Upadacitinib uses
Professional Resources
Monograph (AHFS) Prescribing information	Monograph (AHFS) Prescribing information
Related Treatment Guide
Alopecia Rheumatoid Arthritis COVID-19	Crohn's Disease Ankylosing Spondylitis Atopic Dermatitis Non-Radiographic Axial Spondyloarthritis Polyarticular Juvenile Idiopathic Arthritis Psoriatic Arthritis Rheumatoid Arthritis Ulcerative Colitis show all

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

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Comparing Baricitinib vs Upadacitinib

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