Comparing Advil PM vs Benadryl
| Advil PM (diphenhydramine / ibuprofen) | Benadryl (diphenhydramine) |
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| Advil PM (diphenhydramine / ibuprofen) | Benadryl (diphenhydramine) |
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Over-the-counter
Prescribed for Insomnia, Pain. Advil PM may also be used for purposes not listed in this medication guide. |
Prescription and OTC
Benadryl is used to treat allergies, motion sickness, and to relieve symptoms of Parkinson's Disease (PD) in patients unable to tolerate more potent agents. It may also be used off-label to help... View more |
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| More about Advil PM (diphenhydramine / ibuprofen) | More about Benadryl (diphenhydramine) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Advil PM has an average rating of 7.1 out of 10 from a total of 20 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 20% reported a negative effect. |
Benadryl has an average rating of 7.0 out of 10 from a total of 79 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 20% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Advil PM side effects |
View all Benadryl side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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N/A |
N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Advil PM prices |
View all Benadryl prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other diphenhydramine / ibuprofen brands include: Ibuprofen PM, Motrin PM | Other diphenhydramine brands include: Aler-Dryl, Aler-Tab, Aller-G-Time, Allergia-C, Allermax, Altaryl, Aurodryl Children's Allergy, Banaril, Banophen, Beldin, Belix, Ben-Tann, Benadryl Allergy, Benadryl Children's Allergy, Benahist-10, Benahist-50, Benoject-50, Buckley's Bedtime, Bydramine, Calm-Aid, Complete Allergy Relief, Compoz Nighttime Sleep Aid, ConRx Allergy, Dicopanol, Diphedryl, Diphen, Diphen AF, Diphen Cough, Diphenadryl, Diphendryl, Diphenhist, Diphenmax, Diphenydramine Quick Melt, Diphenyl, Diphenylin, Dormin, DPH, Dytan, Dytuss, Genahist, Help I Can't Sleep, Histaprin, Hydramine, Hydramine Compound, Hydramine Cough Syrup, Hyrexin, Miles Nervine, Nytol, Nytol Caplet, Nytol QuickCaps, Pharbedryl, Scot-Tussin Allergy, Siladryl Allergy, Silphen Cough, Simply Sleep, Sleep Tab II, Sleep-ettes D, Sleepinal, Sleepwell 2-nite, Snooze Fast, Sominex, Sominex Maximum Strength Caplet, Trux-adryl, Twilite, Unisom Liquid, Unisom SleepGels, Unisom SleepMelts, Unisom SleepMinis, Valu-Dryl, Vanamine PD, Vicks QlearQuil Nighttime Allergy Relief, Z-Sleep, ZzzQuil View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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9.3 hours |
9.3 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 756 drugs are known to interact with Advil PM:
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A total of 448 drugs are known to interact with Benadryl:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 21, 2005 |
March 04, 1946 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.