Comparing Acetaminophen / Codeine vs Naproxen
| Acetaminophen / codeine | Naproxen |
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| Acetaminophen / codeine | Naproxen |
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Prescription only
Acetaminophen/codeine may be used to treat mild-to-moderate pain that is unrelieved by nonopioid analgesics. However, the codeine component of this combination medicine is addictive and may cause... View more |
Prescription and OTC
Naproxen is effective for the short-term relief of pain and inflammation associated with arthritis, gout, menstruation, and tendonitis; however, like other NSAIDs, it has the potential to adversely... View more |
Related suggestions Osteoarthritis
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| More about Acetaminophen / codeine | More about Naproxen | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Acetaminophen / codeine has an average rating of 4.8 out of 10 from a total of 231 ratings on Drugs.com. 33% of reviewers reported a positive effect, while 47% reported a negative effect. |
Naproxen has an average rating of 6.8 out of 10 from a total of 683 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 25% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Acetaminophen / codeine side effects |
View all Naproxen side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Acetaminophen / codeine prices |
View all Naproxen prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Aflaxen, Aleve, Aleve Back and Muscle Pain, All Day Pain Relief, All Day Relief, Anaprox-DS, Comfort Pac with Naproxen, EC-Naprosyn, Flanax Pain Reliever, Midol Extended Relief, Naprelan, Naprosyn, Naproxen Sodium DS, Pamprin All Day Relief View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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3.5 hours |
18 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Multiple
The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 609 drugs are known to interact with Acetaminophen / codeine:
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A total of 451 drugs are known to interact with Naproxen:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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May 31, 1974 |
March 11, 1976 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.