Sunosi for Obstructive Sleep Apnea/Hypopnea Syndrome User Reviews

• Tir...
• November 13, 2020

"I've been taking Sunosi 75 mg for over a week now. The first couple of days, I didn't notice any difference. Normally, I am in bed by 7:30 or 8 PM at the very latest because I could not stay awake. I yawn all day long and am just ready to drop. I can never get enough sleep, even if it's 12 or more hours. On the third day of taking Sunosi, I had to catch myself because I looked at the clock, and it was 10:30 PM. I was not ready for bed, but I forced myself because I knew I would pay for it in the morning. I woke up before my alarm went off at 4 AM. It has been the same every day since. I still yawn occasionally during the day, but I am able to stay up much later and wake up easier in the morning. Thank you, Sunosi!"

• Sle...
• Taken for 1 to 6 months
• July 30, 2020

"I've been taking Sunosi for around two months for OSA. I started at 75 mg daily, and I've been taking 150 mg for about two weeks. It is probably important to note that I also take 250 mg of Nuvigil and 20-60 mg of Adderall daily as well. I started the Sunosi with the goal of stopping the Adderall. My diagnosis is severe OSA with excessive daytime sleepiness. Narcolepsy was ruled out, although I experience restless legs and occasional sleep paralysis. I hold my breath in my sleep and wake up feeling like I am suffocating because I cannot force myself to breathe. I have used a CPAP regularly for more than 10 years, and the data shows that my sleep apnea is well controlled. But even so, I sleep between 15 to 18 hours per day. Sunosi was ineffective at 75 mg. At 150 mg, I am awake but too fatigued to do anything. It has caused anxiety, headaches, excessive sweating, nausea, and diarrhea."

• Edd...
• Taken for less than 1 month
• November 16, 2019

"First day took half of 75 mg. Went home and took a nap. Woke up and took the other half, still went to bed a few hours later. Medicine had no effect on me. Got up the next morning, took a whole 75 mg in the morning. Felt sleepy on my way to work an hour later. Felt okay through the morning at work, but when the afternoon came, it all changed. I got sleepy and very agitated. I felt like I hadn’t slept in 3 days, but my eyes were forced open. I felt terrible and was very angry and bothered. Tried a whole again the next morning. Here I am laying on the couch ready to take a nap 5 hours later. I feel like the medicine has no effect whatsoever other than annoying me and keeping my eyes open when my body desperately wants sleep."

• Ms ...
• Taken for less than 1 month
• September 20, 2019

"Sunosi doesn’t work for me. It’s been about a week at 150 mg. It makes me crash hard at the end of the day (around 4 p.m.). At the end of the day, I’m more tired than if I didn’t take it at all. I’ve been waiting for this “miracle medication” for a few months, and I’m disappointed. Nuvigil was great, but it stopped working."

• Orl...
• Taken for less than 1 month
• August 9, 2021

"I have used my CPAP religiously. But even after starting CPAP, I was still exhausted. After work was a nap until I had to go pick up my husband. My lunchtime was a nap. Getting out of bed in the morning was considered cruel and unusual punishment. I had decided to just live with it. But then one of my doctors suggested Sunosi. I was a little skeptical, but desperate to stay awake longer. The 75 mg didn’t have much of an effect on me, but boy, the 150 mg has been life-changing! I’m thinking more clearly, daytime napping is gone, and I’m able to get to sleep at a decent hour because I haven’t napped. It’s wonderful to feel like a normal human instead of constantly being exhausted."

• AJP...
• Taken for 1 to 2 years
• June 4, 2024

"5 stars! I've been on a daily dose of 75 mg for almost 2 years. I've experienced no side effects nor formed a habit. The brain fog that accompanies OSA lifts completely within 20 minutes of ingestion. No jitters, no anxiety but I did lose a few pounds. In my opinion, Sunosi should be made available to those suffering from peri-menopausal and menopausal symptoms like fatigue and brain fog. This medication has been a huge game changer for me."

• Sle...
• April 24, 2021

"I have OSA and use a CPAP. I also have severe RLS, which is treated with oxycodone. I am constantly tired. I heard about Sunosi and asked my doctor about prescribing it for me. She first wanted to try modafinil. This did absolutely nothing and actually made me feel worse from the side effects, which I found later that oxycodone and modafinil have “major” interactions. (Not sure how my doctor or the pharmacist dropped the ball on that one). So finally, my doctor agreed to try the Sunosi. Started at 75 mg, felt absolutely nothing good or bad. After several days, went up to 150 mg, still no improvement in my sleepiness after several weeks of trying. I’m now weaning off (as recommended by my doctor) since the medication did nothing for me, and I feel awful. I’ve been having panic attacks, and my heart rate has been elevated, and I also feel achy all over! Not sure if anyone else has had this experience trying to get off the medication, but I feel worse than ever!"

• LMa...
• Taken for 1 to 2 years
• July 18, 2021

"Been on Sunosi 150 mg daily for approx. a year and a half. Initially, seemed to work pretty well. No more daytime sleepiness and fatigue. As time has passed, the positive effects I used to experience have evaporated. I take a dose early in the morning, and I'm falling asleep by 10:00 a.m. I had the same results with a 200 mg daily dose of Modafinil, which I took before the Sunosi. Frustrating."

• Anonymous
• Taken for less than 1 month
• September 29, 2021

"This medicine is changing my life for the better. I used to wake up in the morning, and within 30 minutes, I was back asleep. I couldn’t hold my eyes open and would sleep all day. Until I started taking this medicine, I’m like a new person. I am on 150 mg."

• Pat...
• Taken for 1 to 6 months
• January 1, 2025

"I used to sleep 12-18 hrs per day yet was always exhausted/never refreshed. Using the 150 mg dose helps me sleep less and feel alert during the day. It does keep me awake many nights, I experience dry mouth and jaw clenching. It might contribute to my recurring dizziness."

• Use...
• Taken for 2 to 5 years
• May 9, 2023

"I have been on max dose for 2+ years. It has never provided me any benefit whatsoever. I have stayed on it because I am so desperately exhausted. I do have other health issues that cause severe exhaustion: hypotension, ME/CFS, fibromyalgia, primary Sjögren's syndrome, POTS, now early stage lupus, and absolutely no help or hope from any of my doctors. My rating is 1 out of 10."

• She...
• Taken for 1 to 6 months
• November 23, 2024

"It works very well. I have noticed I sleep better and don't wake feeling like my mouth and tongue have been in the desert. My RX is for 150, but I often only take 75 mg. I also don't take it every night, usually only when I work. (Yeah, I'm one of those night shift people.) It also seems to help with shift worker problems. I haven't noticed any side effects. I have been using it for a couple of months."

• Fro...
• Taken for 1 to 6 months
• August 2, 2021

"I’ve been taking Sunosi for a month. I started at 37.5 mg and worked up to 150 mg. Sunosi has been keeping me awake during the day, but both my heart rate and BP are elevated. Insomnia is also becoming a problem. My doc lowered my dose to 75 mg, but I still have elevated heart rate and BP. I’ll probably have to stop the medication. Disappointing! I had the same problem with Nuvigil and Provigil."

• Bob...
• Taken for 1 to 6 months
• May 8, 2023

"Have obstructive and central apnea and have been diagnosed with hypersomnia. Have taken Adderall for close to 30 years, currently 60 mg but as high as 90 mg. Even with a CPAP, tired all day. Last 8 years really needed to start taking naps mid-day. Has Provigil added, and at first, it helped. Dropped the Provigil and prescribed Sunosi. I have to say that at 75 mg, this has been effective and keeps me up throughout most days without a nap."

• Bus...
• Taken for 2 to 5 years
• June 29, 2024

"I’ve been on CPAP since about 2005. After years on this, I started having trouble staying awake. I would recognize the feeling before I would start getting drowsy. My job is my life, I drive a school bus. My doctor said we could try Sunosi, 75mg. He told me about the pros and cons, but it worked, and most days I only need half a pill. No side effects. I’ve used it for 3 years. Now I’ve got to start over because my insurance will not approve my prescription."

• Rau...
• Taken for 1 to 2 years
• April 1, 2024

"It might work for a couple of days, then the helpful effect of keeping me alert stops, and I have to stay off it for an interminable amount of time before it returns to being effective. But while the positive effects may wane, the negative effects of nausea, depression, and insomnia may linger for hours. Worse, I have to wait up to 2 hours to discover if Sunosi - 75mg - will work that day. Thankfully, I have a doctor who understands this and gave me a prescription for Adderall, which works unconditionally."

• Rob...
• Taken for less than 1 month
• July 10, 2022

"Excessive daytime fatigue. I tried armodafinil 150 mg first, and it worked well by the second week, then energy uptake stopped, and I suffered through pounding heart, restlessness, anxiety, and nausea. Next was Sunosi 75 mg. It skipped the ‘energy’ part and went straight to all the awful side effects. I held on to it for about 10 days before it was intolerable. Now taking Adderall, 10-15 mg, once a day. I experience a window of energy for about 2 hours (nothing excessive, just alert like after a good night's sleep, which I haven’t had for 2 years). Sometimes with the med, I experience a ‘crash’ of agitation and exasperated cervical dystonia, but that was pre-existing and is usually non-existent because of treatment therapy. The side effects of the non-amphetamine drugs were too much to tolerate, with little relief. I will stick to the occasional Adderall, which I take every 2-3 days, when my responsibilities become backlogged due to my inertia."

• Jus...
• Taken for 1 to 6 months
• October 3, 2021

"Sunosi was not my friend. Did help me stay alert, gave me an internal feeling of agitation. I appeared anxious but never felt any anxiety. At the end of the day, I always had a crash effect but never felt any type of kick-in effect after taking it in the morning. My hands would twitch, and I would type incorrectly on the keyboard while working, and the mouse would fly. All extremities had tremors. My sleep was only 3-4 hours a night. This was the only medication that ever gave me a single-digit score on a sleep questionnaire with my doctor, but the side effects were horrible. I’m now taking something else."

• Kat...
• Taken for 6 months to 1 year
• August 6, 2021

"I started using Sunosi about 6 months ago. I started out on 75 mg and upped the dosage to 150 mg. I know you are supposed to take it in the morning, but it does not get me through an entire day. So I started taking it around noon or 1 PM, and that has worked well for me. If I know I am going out for the evening, I will take another one around 5-6 PM to get me through the night until about 11 PM. What I like is not having any side effects. Unfortunately, my insurance won't pay for Sunosi, so I am being forced to switch to Nuvigil, which is a narcotic, so I am not happy about that. My doctor was giving me free samples (thank goodness). I would recommend Sunosi to anyone, in fact, I am going to see if I qualify for their $9.00 coupon for a year because I don't want to take a narcotic."

• Gar...
• Taken for 1 to 6 months
• July 14, 2023

"Initially I took the 75 mg dose. Had decent results for about a week and then became less effective, although it still was better than nothing. Increased to the 150 mg dose and experienced similar results, but began to have diarrhea with such regularity that I would rather be sleepy. I was going to drop back to 75 mg to get some of the benefit and see if the poop problem got better, but the coupon would no longer work and my cost was going to be $150 a month, which I refuse to accept."

• Rob...
• Taken for 6 months to 1 year
• November 11, 2022

"We are not really sure of what my diagnosis is. One doctor says the circadian clock no longer works because of the hypothetic dysfunction, the other says OSP. Side note: 20 mg of sildenafil an hour before bedtime will bring you down to one or fewer events per hour. I am on sildenafil 20 mg for pulmonary hypertension. Sunosi was the third medication they tried on me for awareness. The first two did not work. My doctor slowly got me to 150 mg. It worked for about 2 weeks. Now I take it before walking my dog at 6:30 a.m., and by 8 a.m. I am out in a deep sleep for at least 5 hours. All of our bodies are different. The problem with chronic fatigue is no one agrees on the source. Until we learn to treat the source, this is all a guessing game. Also, be careful because it can raise your blood pressure. I am on a blood pressure medicine, and two with side effects to lower your blood pressure. I average about 170/90, and my cardiologist said there is nothing which can be done."

• Sle...
• Taken for less than 1 month
• April 16, 2022

"My PA gave me a couple of samples of Sunosi 150 mg because I told him I was still sleepy during the day even though I've been on CPAP steadily for over a year. I'd seen the TV ads for Sunosi, so I had high hopes for it. Unfortunately, it's been a disappointment. I'm only somewhat less sleepy during the day since I've been taking it. I still find myself fighting sleep during what are supposed to be 'waking' hours. On the plus side, though, I haven't had any side effects from it. I'll just have to find something else."

• Way...
• Taken for 1 to 6 months
• November 3, 2021

"Sunosi was okay, but it is too small a dosage for my taste. I would like to try one dose in the morning (around 6 a.m.) and one dose around 12 noon."

• AJP...
• Taken for 1 to 2 years
• April 29, 2022

"A true game changer. The brain fog has lifted and without any side effects."

• RAL...
• Taken for 1 to 6 months
• February 13, 2024

"Seems to help. Not 100%. Biggest problem is cost. On Medicare & have not found a good price."