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Januvia and Swelling: What Users Say

Swelling: mentioned by 8 users (5.8%)

Based on user experiences from 139 Januvia reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

diarrhea 11.5%
joint pain 8.6%
nausea 7.9%
upset stomach 6.5%
shortness of breath 5.8%
swelling 5.8%
vomiting 5.8%
constipation 4.3%
insomnia 4.3%
stomach pain 4.3%

Reviews for Januvia

Commonly mentioned side effects
  • ddw...
  • May 13, 2015

For Type 2 Diabetes "The doctor put me on Metformin, which my liver didn't fare well with, and then tried the Januvia 100 mg. After 2.5 weeks, I told him I was experiencing facial, hand, and eyelid swelling and that I felt this wasn't a good fit for me. So, he prescribed Januvia 50 mg, which after three days, caused nausea, upper abdominal pain, orange urine, and skyrocketing blood glucose from low 120's to well over 200's after eating. I immediately quit taking it."

2 / 10
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  • ddw...
  • May 13, 2015

For Type 2 Diabetes "The doctor put me on Metformin, which my liver didn't fare well with, and then tried the Januvia 100 mg. After 2.5 weeks, I told him I was experiencing facial, hand, and eyelid swelling and that I felt this wasn't a good fit for me. So, he prescribed Januvia 50 mg, which after three days, caused nausea, upper abdominal pain, orange urine, and skyrocketing blood glucose from low 120's to well over 200's after eating. I immediately quit taking it."

2 / 10
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68 Report
  • Nei...
  • Taken for 1 to 6 months
  • September 14, 2019

For Type 2 Diabetes "My A1C was under 7 with Metformin and Starlix. My Dr. added Januvia 100 mg. My A1C increased over 7. The worst part was, my eyes started itching badly and got swollen. Once I stopped Januvia, my eyes got normal again."

1 / 10
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34 Report

Frequently asked questions

  • yuk...
  • Taken for 1 to 2 years
  • August 29, 2016

For Type 2 Diabetes "Januvia side effects include crippling, debilitating pain and swelling. Dad's been taking it since March 2015, and by August could barely walk. He had joint swelling and excruciating pain. Doctor after doctor visit. No clue! Called me, his daughter, RN BSN, and we returned to the doctor wanting to know why he didn't know more about this drug's side effects. NONE OF THEM DO! A friend veteran, same thing. Could hardly stand the pain, talking about swollen and angioedema. They even ran heart tests! It was the Januvia, and my dad and the vet, taken off Januvia, have completely recovered. The veteran had even been referred to a rheumatologist. My dad is now taking chromium type supplements and watching his carbs. Doing very well."

2 / 10
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47 Report
  • yuk...
  • Taken for 1 to 2 years
  • August 29, 2016

For Type 2 Diabetes "Januvia side effects include crippling, debilitating pain and swelling. Dad's been taking it since March 2015, and by August could barely walk. He had joint swelling and excruciating pain. Doctor after doctor visit. No clue! Called me, his daughter, RN BSN, and we returned to the doctor wanting to know why he didn't know more about this drug's side effects. NONE OF THEM DO! A friend veteran, same thing. Could hardly stand the pain, talking about swollen and angioedema. They even ran heart tests! It was the Januvia, and my dad and the vet, taken off Januvia, have completely recovered. The veteran had even been referred to a rheumatologist. My dad is now taking chromium type supplements and watching his carbs. Doing very well."

2 / 10
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47 Report

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  • yuk...
  • Taken for 1 to 2 years
  • August 29, 2016

For Type 2 Diabetes "Januvia side effects include crippling, debilitating pain and swelling. Dad's been taking it since March 2015, and by August could barely walk. He had joint swelling and excruciating pain. Doctor after doctor visit. No clue! Called me, his daughter, RN BSN, and we returned to the doctor wanting to know why he didn't know more about this drug's side effects. NONE OF THEM DO! A friend veteran, same thing. Could hardly stand the pain, talking about swollen and angioedema. They even ran heart tests! It was the Januvia, and my dad and the vet, taken off Januvia, have completely recovered. The veteran had even been referred to a rheumatologist. My dad is now taking chromium type supplements and watching his carbs. Doing very well."

2 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • May 27, 2023

For Type 2 Diabetes "When used with Metformin, I had stomach pain, diarrhea, vomiting, nausea. Without Metformin, I now have a constant backache, leg swelling, increased appetite. I was losing weight before, now I am gaining it back while sticking to my diet. My dosage is 100 mg, once daily, and my blood sugar is still not under control."

3 / 10
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  • Anonymous
  • Taken for less than 1 month
  • July 7, 2017

For Type 2 Diabetes "Developed neck swelling within a week, could not breathe, went to ICU, trachea closed."

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.