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Simvastatin and Joint Pain: What Users Say

Brand names: Zocor, FloLipid

Joint pain: mentioned by 6 users (4.6%)

Based on user experiences from 131 Simvastatin reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

insomnia 11.5%
pain 11.5%
weakness 9.2%
cramps 8.4%
muscle pain 8.4%
tiredness 7.6%
headaches 6.9%
depression 6.1%
heart palpitations 4.6%
joint pain 4.6%

Reviews for Simvastatin

Commonly mentioned side effects
  • Joh...
  • Taken for 10 years or more
  • June 29, 2015

Zocor (simvastatin) for High Cholesterol "Started this med about 11 years ago. It dropped my level to below avg. I always associated my aches and pains to my age and activity level, but I've discontinued its use for about 3 weeks because my finger joints felt swollen and arthritic. I'm starting to feel a slow improvement. My additional symptoms are sore hips and other joints. To be fair, I won't be able to discern whether this is the drug or some other factor until staying off it longer."

7 / 10
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76 Report
  • tmi...
  • Taken for 1 to 6 months
  • July 11, 2013

For High Cholesterol "Since I started taking simvastatin 20mg at bedtime, I am not sleeping well, joint pain, tiredness, and my acid reflux is so bad I can't stand it anymore. Not sure if the simvastatin is the problem, but was not having the issues with my acid reflux while taking my Nexium until I started taking simvastatin. Talked with my pharmacy, and they told me that the simvastatin does not worsen acid reflux. It does seem funny. I was not having a problem with it until I started taking the simvastatin."

2 / 10
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86 Report
  • Anonymous
  • July 20, 2011

For High Cholesterol "I've been on Lipitor and now simvastatin 80mg for the past 13 to 15 years. For most of these years I have had no side effects and my cholesterol went down from 238 to 104.2. I was exercising pretty regularly. However, during this past year I have started to feel a lot of joint pain in my shoulders and now in my hips. I used to walk and run on my treadmill and take walks with my wife but because of the hip pain I'm experiencing I no longer can walk farther than around the block. I also get very tired after about 3 to 4 hrs from getting up in the morning and need a nap. I am 60 years old."

7 / 10
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68 Report

Frequently asked questions

  • Anonymous
  • Taken for 1 to 6 months
  • September 18, 2012

For High Cholesterol "It lowered my cholesterol from 258 to 221 after one month, but I have numbness in my extremities and pain in my ankles. I wake up with numb limbs and sore ankles every day since I started taking this."

4 / 10
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63 Report
  • Anonymous
  • July 29, 2009

For High Cholesterol "Been taking this for 4 months. Having joint pain and abdominal issues. Going to take a break to see how it gets better. Used to take Lipitor without issues."

5 / 10
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36 Report
  • RCA...
  • April 15, 2011

For High Cholesterol "For me, only simvastatin by Cobalt Labs did not cause severe muscle and joint pain. The others contain a filler that causes the pain."

10 / 10
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21 Report

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