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Ozempic User Reviews & Ratings

Ozempic has an average rating of 6.4 out of 10 from a total of 1,095 reviews on Drugs.com. 50% of reviewers reported a positive experience, while 27% reported a negative experience.

Reviews for Ozempic

  • Smithy...
  • Taken for 1 to 6 months
  • March 14, 2023

For Weight Loss (Obesity/Overweight) "I was hesitant to try Ozempic for weight loss (need to lose 30 lbs) because I have a lot of kids/responsibilities and don't have the time to be nauseous or have debilitating diarrhea, etc. After keeping the pen in the fridge for weeks, I decided to risk an injection, and I'm so happy to say I've had zero side effects except a disinterest in food. I'm on week six of the 0.25 dose because it's enough for me, and I don't see a reason to increase the dose. My lack of interest in food is liberating! For the first time in 30 years, I don't go to bed kicking myself for what I've eaten or making promises to myself to make amends for overeating. Zero sugar cravings...food isn't a reward or pleasure anymore. I'm never ravenous, so I make good, calm choices about what I eat. This has been life-changing and a complete shift in perspective. Obviously, some people have terrible side effects, but I've had none (not even a headache!)."

10 / 10
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  • Doubt...
  • January 19, 2021

For Diabetes, Type 2 "I took one Ozempic injection at 0.25 and ended up at the ER 2 days later. I had horrible bloating. Burping smelled like eggs. Unstoppable vomiting and diarrhea. I ONLY TOOK ONE INJECTION and stopped the medicine. It has been 2 weeks and the medicine is still making me sick. I'm just wondering how long it takes to fully leave your system? I just want to feel human again. I was tested for pancreatitis but was okay, but the doctor said they will repeat labs soon. I DON'T RECOMMEND THIS MEDICATION TO ANYONE. PLEASE BE SAFE TAKING THIS MEDICATION."

1 / 10
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711 Report
  • Mac
  • October 18, 2020

For Diabetes, Type 2 "Ozempic has caused me so much constipation!!! I know a side effect is diarrhea, but it does the complete OPPOSITE for me. A day or two after I take my injection, I have no bowel movements at all!! Every week I am forced to take a laxative. It has caused so many problems for me. Anyone else experienced severe constipation. So frustrated."

1 / 10
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Frequently asked questions

  • Conce...
  • Taken for 1 to 6 months
  • February 1, 2021

For Diabetes, Type 2 "I started Ozempic in late December at 0.25 injection. I also take 500mg metformin per day. Soon after I started Ozempic, I had decreased appetite and my sugars improved, but I had reflux, gas, bloating, nausea, and diarrhea. After 4 weeks, I started 0.50. 2 weeks in, I have bouts of painful constipation then diarrhea, nausea, bloating, gas, reflux, and cramping. I've almost vomited a few times. When I eat, it feels like the food just sits and sits, barely moving through my gut. My doctor wants me to stick with it, saying that these side effects usually improve, but it's been pretty miserable. I'm thinking I'm going to stop taking it. While Ozempic has been effective in regulating my sugars and losing weight, I don't think it's worth the suffering that I've been enduring on this medication. I understand that studies showed it causing thyroid cancer in mice, but no one knows if it causes thyroid cancer in humans. I don't want to be the guinea pig the drug makers use to find out it does."

5 / 10
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  • Saucy
  • December 3, 2020

For Diabetes, Type 2 "Been on Ozempic since mid-April 2020. All side effects listed with the worst being chronic diarrhea. Nausea has been significant but has settled to occasionally. Trying to follow a more plant-based diet, I have lost today an official 60 pounds. I find the less meat I eat, the more energy I have, the better my blood sugars are as well. I am 53, so weight loss isn't impossible for us older ladies..."

7 / 10
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Are you taking this medicine?

  • Margie
  • September 27, 2020

For Diabetes, Type 2 "I was put on Ozempic after taking Glimepiride for several years. I started on 0.25mg, then onto 1mg. I started having the nastiest burps ever, then diarrhea 3 to 4 times a day. After 3 months, I went to a gastroenterologist and was diagnosed with gastroparesis, a side effect of Ozempic. I have all the side effects - nasty, offensive-smelling burps, eye floaters in both eyes, bad diarrhea, stomach pain, and now this disease that has caused precancerous cells. Yes, my appetite has decreased, I have lost 15 lbs in 3 months, and my numbers are good. But it's not worth being sick every day. I just found out my daughter is going through the same exact thing. So, take it at your own risk."

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  • JEano
  • Taken for 1 to 6 months
  • August 26, 2020

For Diabetes, Type 2 "I have been taking Ozempic for 4 months to reduce insulin resistance (caused by polycystic ovary syndrome). The medication has significantly reduced my appetite. I have had a few minor side effects - a stomach cramp here, an episode of diarrhea there...but nothing at all significant. My weight went from 151 (BMI 25.9) to 133 three months later (BMI 22.8). I honestly could not be happier."

10 / 10
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364 Report

More FAQ

  • Lynn
  • December 22, 2020

For Diabetes, Type 2 "I took one dose of Ozempic and I have been sick ever since. Diarrhea, vomiting, nausea, stomach cramps, and a little dizziness. This is terrible, will never use again. Can someone tell me how long these symptoms last?"

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  • Aila
  • Taken for 1 to 6 months
  • January 4, 2021

For Cardiovascular Risk Reduction "I went on Ozempic for weight loss after being told by a friend of mine about it - she started at 280 lbs and lost 60+ pounds. My whole life I’ve always been about 130 pounds, and then I rapidly gained 50 pounds within about 2 years. I started taking Ozempic at 182 pounds (I’m 5’4) and 6 months later I am down 25 pounds and continuing to lose. I could not recommend this drug more. It INTENSELY reduced my appetite and obsession over food. Aside from some occasional nausea (maybe once every 2 weeks), and some diarrhea, nothing that I can’t handle, the drug has been pretty great. This is only my experience though!"

10 / 10
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  • Amanda
  • Taken for 6 months to 1 year
  • December 16, 2021

For Diabetes, Type 2 "Listen to me, Ozempic will change your life, but you cannot eat synthetic sugar at all. I had severe Hashimoto's, PCOS, insulin resistance, and severe diabetes symptoms. HbA1c was high, all cholesterols were high despite the healthiest of diets. My numbers cleared from severe to perfect in 1 month! I had full-body swelling, severely cracked ankles, swollen feet, neck, legs, major hair loss... a nightmare. I began taking Ozempic. I was very sick. It made me extremely nauseous. I got severe diarrhea, but let me tell you, I lost 17 pounds of water weight in one month. My doctor couldn’t believe it. In four months, I lost 40 lbs. The nausea was mild to severe the entire time, but the results were borderline insane. It reset my metabolism, took all of the inflammation away from my joints, neck, back, my feet completely healed within one month. It’s barely believable. I spent two months on 0.25 and increased to 0.5 once a week for ten more months. High praise!"

10 / 10
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  • Nw272...
  • Taken for 1 to 6 months
  • June 20, 2021

For Diabetes, Type 2 "Started April 1, 2021, on Ozempic low dose. 3-week intervals it was increased. Side effects were constipation (went on laxatives to help), pain in my back (severe), bloating. Week 11 increased to 1mg, the side effects were major bloating, diarrhea, sounds in my stomach (crazy), nauseous, feeling under the weather. My appetite has decreased to the point that I only eat 2 meals a day that are small. My sugar levels have decreased from 7.1 to 5.2 A1C. I’ve noticed that I have been kept awake some nights like I’m nervous for some reason. In the first 3 weeks, I’ve lost 15 pounds. Haven’t checked since I want to wait but can feel a difference. The pains in the stomach are really uncomfortable, and the bloating I will try gas-x for relief. When I try to eat more than I should, my body tells me that I’m full. If I go beyond that point, I get severe pains in the stomach for hours. But depends on what I eat. Going to stay with smaller portions/healthier foods."

8 / 10
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  • Janny
  • Taken for 1 to 6 months
  • March 15, 2021

For Diabetes, Type 2 "My doctor gave me Ozempic 0.5 to start with. I always had upset stomach, diarrhea with most foods, and an overall sick feeling all the time. I was able to 'live' with it until now. She decided to up my dose to the 1.0 and my body went into total chaos. I am always nauseous, constipated, got reflux, feels like my food is stuck in my stomach and doesn't go anywhere. I'm constantly burping and feeling bloated. The sick feeling feels intensified and I cannot function at work. I took my last one this past Friday night and was miserable all weekend long. Today I am at work unable to function at my best because the nausea is bad. I would say it is effective in lowering your blood sugar numbers and helping you lose weight but not worth feeling horribly sick over. I will not be using this medication any longer."

5 / 10
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  • SooGirl
  • Taken for less than 1 month
  • July 8, 2021

For Cardiovascular Risk Reduction "I've been on Ozempic for just over a week now as part of a physician-run weight loss program. I was told to expect some GI upset, but I had no idea it would be this bad. Seven days after taking it, I started with diarrhea. One day after injection number 2 (2.5mg), I was up all night with diarrhea, nausea, severe reflux, belching, and eventually vomiting. Medications like Pepto can't seem to touch it. I am going to talk to the doctor next week and see what he thinks. I really don't think it is worth this kind of suffering."

2 / 10
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  • SHano
  • Taken for less than 1 month
  • February 2, 2021

For Diabetes, Type 2 "I feel that the best practice for this medicine would be to take about only 8-10 clicks (17 clicks = 0.25) for the first several weeks and then build yourself up to the full 0.25 dose. That way you can see what side effects you are going to experience and if they are tolerable or not. I took 0.25 and suffered from severe diarrhea for almost the full 7 days. Ended up in the hospital for the last 4 days until the side effects wore off. The only positive was that I lost almost 20lbs. I would be very careful taking this medicine."

1 / 10
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  • Kris
  • Taken for less than 1 month
  • July 2, 2023

For Weight Loss (Obesity/Overweight) "This drug affects everyone differently, but for me, the side effects were too bad, and I had to stop after 2 weeks. It totally worked by killing my appetite and making me feel full, and after the first week, there were days I didn't even want to eat at all. I lost about 8 pounds in two weeks, which is great. However, during the 2nd week, I got the worst upset stomach of my life and almost went to the ER. I had intense diarrhea for an entire day, along with nausea, the chills, a swollen stomach, and then sweating. I had to take a sick day from work because I was also dizzy, and my heart was racing. It finally subsided about a day and a half, but it scared me so badly that I stopped taking the drug. Now I understand why it has a black box warning. I'm happy for the people who can use this without bad side effects. For me, I have a young child and demanding job. I can't go around with symptoms of food poisoning and try to act like I’m ok."

4 / 10
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  • Annie...
  • Taken for 6 months to 1 year
  • September 9, 2019

For Diabetes, Type 2 "Hi! Have been on Ozempic for 10 months. The first 3 months were very difficult with strong side effects. Mainly constant, but low level, nausea, occasional vomiting, and diarrhea (especially two days after the injection). However around month 3 the nausea and diarrhea subsided greatly and my appetite returned. I had lost weight very quickly (42 lbs in 3 months due to not really eating much). Had to take supplements for a while but am now eating well. The rapid weight loss led to telogen effluvium, a temporary hair loss condition. (I shed A LOT but never showed any baldness or anything). Currently, my weight is still down (I was taken off my blood pressure medication!), my blood counts are perfect, my hair is getting thick, and I eat normally. I now experience virtually no side effects. Really, really, glad I stuck out the side effects at the beginning."

7 / 10
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  • Ozempic
  • Taken for less than 1 month
  • May 14, 2023

For Weight Loss (Obesity/Overweight) "With just one 0.25 mg dose I became very ill. Relentless nausea, vomiting, and explosive diarrhea as well as unbearable stomach cramps. Needed to go to the ER for fluids and to check for pancreatitis. It’s now been 9 days since my first dose and I still have relentless diarrhea, nausea, and disabling fatigue. I don’t want to eat. I didn’t want to take it in the first place but was ambushed by my kidney doctor. She told me that using Ozempic was a no-brainer and that I would just have a bit of nausea. If you have any gastrointestinal symptoms when taking any medicine, I would think three times about it before using it. I have read it can take up to a month for it to be flushed out of your body but I am hoping and praying that these horrible side effects stop real soon."

1 / 10
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  • Bears...
  • Taken for 1 to 6 months
  • January 7, 2021

For Diabetes, Type 2 "I have been on Ozempic for 6 months now. After the first few injections, I was so sick vomiting and diarrhea all the time. I called the doc and said I couldn’t take this anymore. Of course I lost weight, as I couldn’t keep anything in me. I researched the medication itself to understand exactly what it was & how it worked. I decided to stay on it. My A1c was 8.8 when I started. 3 months later, 6.4. I am down 36 pounds. I have been exercising regularly for 3 months now, running 3.5 miles 5 X a week. The confidence and energy from the weight loss outweighs all the negative side affects in the beginning for me! Blood sugar control is excellent, and I suspect will only improve after the continued weight loss. I have stalled with weight loss twice now, but not giving up, and sticking to my exercise (changing it up a bit to gain more muscle to burn fat), I have been able to overcome the stalls and continue to lose. Complete game changer medication for me!!"

8 / 10
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  • Dannie
  • Taken for 1 to 6 months
  • March 24, 2019

For Diabetes, Type 2 "I’ve been on this med for 7 weeks. I’ve lost 25 lbs and my daily blood sugars range from 60 - 90. I use it along with 500 mg Metformin. The first couple of weeks were hard with nausea and stomach cramps. I also had the headaches that others have mentioned in the first couple of days. In week 3, I increased from 0.25 to 0.50. Then came the diarrhea. It wasn't too bad; I was just happy that I could go. I’m now taking 1.0 and experiencing sulfuric burping. Ugh! After doing some research on home remedies to help with the burping, I’m trying a spoon of apple cider vinegar. If you can make it through the first few weeks and you can be somewhat disciplined, you will notice a huge difference in how you feel. In my opinion, the side effects are manageable when I compare the weight gain while taking Insulin. BTW - I’m not severely obese. Prior to being on this drug, my weight was 205, and I’m 5’9 and 47 years old. I hope this is helpful to someone."

9 / 10
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  • TED...
  • Taken for 6 months to 1 year
  • September 9, 2023

For Weight Loss (Obesity/Overweight) "I have been taking Ozempic for 9 months. I am 74 years old, and a workaholic. I simply do not have time to exercise. I am at my computer working between 18 and 20 hours x 7 x 365. This will not change - ever. I got up to 274 lbs. I weigh once weekly. Today I weighed 191 lbs., or a loss of 83 lbs. over the duration - or about 30% of my body weight. Some slight dizziness from time to time which has diminished considerably after the 2nd month. Bad diarrhea for 72 hours after each injection until I discovered this medication does not like fat/grease/fried food of any type - then, some manageable diarrhea thereafter. Dosage .5 mg. Extraordinarily easy to use."

10 / 10
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  • NursD...
  • Taken for 1 to 6 months
  • July 15, 2023

For Weight Loss (Obesity/Overweight) "Ozempic for weight loss is AMAZING! I have tried everything for weight loss since 1985. Ozempic by far is a miracle for me. It immediately blocks cravings, appetite, and thoughts about food! I started June 2, 2023 and today, July 13, 2023, I lost 22.3 lbs. This is a 6-week success story! I took 0.25 for the first week and then 0.5 weekly on Sundays. I have stayed with Weight Watchers, mainly selecting 'free foods'. If you are eating out with friends this summer, remember that rich, high-fat content foods will give you immediate abdominal distress (cramps, diarrhea). So, I've learned to go through restaurant menus and find something less distressful to eat so that I can enjoy time with friends and family. I have Zofran for nausea, but for me, the nausea passes and I do not use anything for nausea. Stay active at least walk! It's free! Keep drinking water and add a packet of electrolytes due to this extreme heat this summer! Check-in with my doctor on a regular basis."

10 / 10
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  • Jobob
  • Taken for 1 to 6 months
  • November 2, 2020

For Diabetes, Type 2 "I have taken opzempic for a month now dosage being 0.25 once a week and at first I didn’t really see any side affects or anything but then boy one day I made the mistake and over ate and had gas constantly and kept burping repeatedly and then and hour later non stop diarrhea. After making that mistake I have taken into account never by any means do that again. I usually now just eat a big breakfast and like a snack later on throughout the day and it’s helped me completely cut out soda entirely. I originally started taking this because I was experiencing rapid weight gain and they checked my thyroid and said it was within normal limits so they put me on this and I am so glad. I wake up in the morning and I haven’t had a blood sugar reading over 130 in a month I can’t wait to go back to my doctor and figure out what my A1C is. But in total I’ve lost 8 pounds in one month :)"

10 / 10
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  • Gymkh...
  • Taken for 1 to 2 years
  • October 8, 2020

For Cardiovascular Risk Reduction "My doctor prescribed ozempic to me a year ago for weight loss. I’m only taking 19 clicks every 2 weeks when I go see my doctor he gives it to me. Every time I get the Ozempic I get sick 2 days later. It starts by nasty burps, then stomach cramps, then out of nowhere I throw up you don’t get a warning, sometimes diarrhea and sometimes I feel like I’m going to pass out. I got the Ozempic Monday and woke up in the middle of the night with nasty burps and stomach cramps."

1 / 10
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  • Miser...
  • Taken for 1 to 6 months
  • May 27, 2020

For Diabetes, Type 2 "Started Ozempic 8 weeks ago, from the beginning I started belching. Doze was .25 went to . 50 and the stomach cramps started. I am in 3 weeks now at 1mg and I have never been more miserable. Constant violent diarrhea and stomach cramps. I am losing weight at a rapid pace didn’t necessarily need to lose. I called the doctor today because I’m unable to leave the house she seems to think that this will subside in another week and I should be back to normal. After reading everyone’s comments I find this hard to believe!!!!"

2 / 10
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  • Onward
  • Taken for 1 to 6 months
  • July 18, 2021

For Diabetes, Type 2 "I am male (early 50s). Blood glucose was already regulated with metformin, diet, and exercise (100 to 150), but I wanted to quit metformin because of its side effects (diarrhea). I was put on 0.50 mg/wk and warned that nausea from Ozempic was a common side effect. I HAD NO IDEA! WEEK 1/WEEK 2: I couldn't smell food without getting queasy. I choked down lots of soup just to get 1200 cal/day (often falling short). WEEK 3/WEEK 4 got slightly better. WEEK 5: I have my appetite back. I feel full, so I eat smaller meals. My weight loss is atypical: 203 lbs to 183 lbs in five weeks, combined with exercise (1 hr/4x wk stationary bike/treadmill). Blood glucose is now between 90 and 120, with occasional dips and peaks. I would only recommend this drug to those who have very high glucose levels, are morbidly obese, fiercely stubborn, and/or desperate. But it works. Good luck."

8 / 10
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57 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.