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Ozempic User Reviews & Ratings

Ozempic has an average rating of 6.4 out of 10 from a total of 1,102 reviews on Drugs.com. 51% of reviewers reported a positive experience, while 27% reported a negative experience.

Reviews for Ozempic

  • Doubt...
  • January 19, 2021

For Diabetes, Type 2 "I took one Ozempic injection at 0.25 and ended up at the ER 2 days later. I had horrible bloating. Burping smelled like eggs. Unstoppable vomiting and diarrhea. I ONLY TOOK ONE INJECTION and stopped the medicine. It has been 2 weeks and the medicine is still making me sick. I'm just wondering how long it takes to fully leave your system? I just want to feel human again. I was tested for pancreatitis but was okay, but the doctor said they will repeat labs soon. I DON'T RECOMMEND THIS MEDICATION TO ANYONE. PLEASE BE SAFE TAKING THIS MEDICATION."

1 / 10
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723 Report
  • Conce...
  • Taken for 1 to 6 months
  • February 1, 2021

For Diabetes, Type 2 "I started Ozempic in late December at 0.25 injection. I also take 500mg metformin per day. Soon after I started Ozempic, I had decreased appetite and my sugars improved, but I had reflux, gas, bloating, nausea, and diarrhea. After 4 weeks, I started 0.50. 2 weeks in, I have bouts of painful constipation then diarrhea, nausea, bloating, gas, reflux, and cramping. I've almost vomited a few times. When I eat, it feels like the food just sits and sits, barely moving through my gut. My doctor wants me to stick with it, saying that these side effects usually improve, but it's been pretty miserable. I'm thinking I'm going to stop taking it. While Ozempic has been effective in regulating my sugars and losing weight, I don't think it's worth the suffering that I've been enduring on this medication. I understand that studies showed it causing thyroid cancer in mice, but no one knows if it causes thyroid cancer in humans. I don't want to be the guinea pig the drug makers use to find out it does."

5 / 10
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503 Report
  • Marsh
  • Taken for 6 months to 1 year
  • April 27, 2020

For Cardiovascular Risk Reduction "Unbelievable medicine - although I was supposed to start with a 0.25 dose and move up to 0.5, I never did. I have stayed on the 0.25 dose and feel amazing. I have lost 30 lbs, don’t have any bad taste in my mouth, no bloating or excess gas. Actually, I can’t find anything bad to say about this medication other than it is expensive. I feel better than I have in years, and my A1C is unbelievable! Keep it up but please make it cheaper!"

10 / 10
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Frequently asked questions

  • Nw272...
  • Taken for 1 to 6 months
  • June 20, 2021

For Diabetes, Type 2 "Started April 1, 2021, on Ozempic low dose. 3-week intervals it was increased. Side effects were constipation (went on laxatives to help), pain in my back (severe), bloating. Week 11 increased to 1mg, the side effects were major bloating, diarrhea, sounds in my stomach (crazy), nauseous, feeling under the weather. My appetite has decreased to the point that I only eat 2 meals a day that are small. My sugar levels have decreased from 7.1 to 5.2 A1C. I’ve noticed that I have been kept awake some nights like I’m nervous for some reason. In the first 3 weeks, I’ve lost 15 pounds. Haven’t checked since I want to wait but can feel a difference. The pains in the stomach are really uncomfortable, and the bloating I will try gas-x for relief. When I try to eat more than I should, my body tells me that I’m full. If I go beyond that point, I get severe pains in the stomach for hours. But depends on what I eat. Going to stay with smaller portions/healthier foods."

8 / 10
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  • Janny
  • Taken for 1 to 6 months
  • March 15, 2021

For Diabetes, Type 2 "My doctor gave me Ozempic 0.5 to start with. I always had upset stomach, diarrhea with most foods, and an overall sick feeling all the time. I was able to 'live' with it until now. She decided to up my dose to the 1.0 and my body went into total chaos. I am always nauseous, constipated, got reflux, feels like my food is stuck in my stomach and doesn't go anywhere. I'm constantly burping and feeling bloated. The sick feeling feels intensified and I cannot function at work. I took my last one this past Friday night and was miserable all weekend long. Today I am at work unable to function at my best because the nausea is bad. I would say it is effective in lowering your blood sugar numbers and helping you lose weight but not worth feeling horribly sick over. I will not be using this medication any longer."

5 / 10
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Are you taking this medicine?

  • vallen
  • Taken for 1 to 6 months
  • May 29, 2020

For Cardiovascular Risk Reduction "I have been using this medication Ozempic for several months. My dose is 1mg per week. This medication has made me feel sick from my first dose. I've lost 15 lbs but have bloating, gas, burping, and most recently hiccups for over a week. I will not be using this medication anymore."

3 / 10
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103 Report
  • Retired...
  • Taken for 1 to 6 months
  • February 25, 2020

For Diabetes, Type 2 "Take my comments for what they are worth since I changed many things in my life at the same time, but I think Ozempic is great. After 5 months, it reduced my A1c from 9.7 to 5.9. I lost almost 25 pounds. I am at 0.5mg, and it has drastically reduced my appetite. Between a smaller stomach and this drug, I often push my plate away before finishing; rarely a desire for dessert. Little to no side effects overall. Some stomach issues like constipation and bloating, but I can't rule out dietary changes being the cause as well. I went on a low-carb diet and really stuck to it for once and increased exercise a lot. The use of the Freestyle Libre Sensor really helped too! Being able to learn how things affect your blood sugar in real time is a great motivator to do the right thing, combine carbs with protein, etc. I am hoping to lower other meds I am on when I see my doctor next month. Once a week, a tiny needle (virtually pain-free) is a far better system than taking pills every day."

10 / 10
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84 Report

More FAQ

  • Pat
  • July 19, 2019

For Diabetes, Type 2 "Started taking Ozempic for pre-diabetes and insulin resistance. This is the first medication I've ever taken for diabetes. A1c was 5.7. I increased the dose quickly at the doctor's recommendation if little to no side effects occurred. First dose 0.25 in the office. Second 0.5 a week later. Third dose at 1.0 a week after that. Only side effect I have is mild nausea. Appetite has disappeared, and I eat only when hungry and much smaller portions. Serious bloating when I eat too much, which is a great deterrent. Been on the medication for 4 weeks overall, 2 weeks at 1.0, weight dropped from 305 lbs. to 295 lbs. Still a little lethargic, but I was very lethargic before starting the medication. I feel like this medicine is a game changer for me. I love not thinking about food all of the time, only eating when hungry and not for pleasure, and losing weight. Will retest A1c in 2 months. Hopefully, the weight loss continues, and I caught the A1c level before it turns into full-blown diabetes."

10 / 10
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  • happie
  • Taken for less than 1 month
  • July 29, 2021

For Cardiovascular Risk Reduction "I am not diabetic but I started using Ozempic for weight loss. I took my first injection 5 days ago and I feel like a different person. I have been energized, great mood, no cravings for sweets and I get full very quickly when I finally do want to eat. I haven't checked my weight yet but I definitely feel less bloated"

9 / 10
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47 Report
  • No...
  • Taken for less than 1 month
  • October 30, 2022

For Cardiovascular Risk Reduction "I’m 5 foot tall, 50, female, perimenopausal, non-diabetic, not prediabetic, 176 pounds. HbA1c is 37 but BMI is in obese range. Started on 0.25mg for 4 weeks. Lost 6 pounds. Definitely curbs appetite for first 3 days but cravings are back by day 4. Will need higher dose. No nausea or other symptoms except bloating when I eat more than one portion. My diet is generally good as I rarely eat junk food and never drink soda or add sugar to anything. My diet is healthier than my skinny friends but my problem is portion control. I’m optimistic this medication will work to curb overeating and head off obesity and diabetes post menopause. Can’t “weight” to see what 0.5mg dose does for me."

8 / 10
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  • XJXJ
  • Taken for 1 to 6 months
  • March 5, 2024

For Diabetes, Type 2 "It really helps, especially if you are eating the correct foods. Sometimes the side effects are feeling really bloated. I started off with 0.25 then moved up to 0.5. Watch your sugar intake though, you may get dizzy spells if too many sweets."

9 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • May 10, 2024

For Diabetes, Type 2 "This medication is working well for me. My blood sugar at last testing was 6.7 from a long-term level of 7.7+. I am down around 50 pounds since I started taking it. I have had problems adjusting to it. I easily go whole days without eating. I sometimes have to force myself to eat. That is sometimes a task. I feel bloated a lot. The smell of food makes me nauseous. Spoonfuls of food make me want to push the plate away. I did have a problem 6 months ago where I went nearly a week without eating. I passed out in my kitchen from dehydration, landed on my face breaking several teeth, and was hospitalized for 5 days. This was after getting my Ozempic switched from 0.5mg to 1mg. I haven't had that kind of problem after moving back to 0.5mg, but not eating at all for 1-2 days is still an issue. I continue to take it because my blood sugar is where I would like it to be and my weight is way down."

8 / 10
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  • Cat
  • Taken for less than 1 month
  • July 10, 2019

For Diabetes, Type 2 "First injected dose Sunday night. Wee hours Monday the nausea started. No vomiting (emetophobic here!) Monday all day nausea that I could handle (took a Zofran), Tuesday afternoon hit with sudden stomach cramping and diarrhea. Those nasty sulphuric burps all Tuesday evening and over night, diarrhea all night and now it’s Wednesday morning and still watery diarrhea. My stomach has been rumbling and terribly bloated since Tuesday afternoon. I need to lose 70 lbs but this is NOT worth it!! Who wants days and weeks of feeling HORRIBLE!?! I’ll lose weight another way! I have sleep apnea and am 56, so want to be healthy but this drug is Not recommended unless you need to lose weight to stay alive. I teach too so there’s no way I can continue this."

1 / 10
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  • Bec_UK
  • December 28, 2020

For Diabetes, Type 2 "I started taking the Ozempic injection a week before Christmas, and took my second 0.25 dose on xmas eve. Ive felt slight nausea since taking it and very little desire to eat. My BS levels have been 95% in range ever since and have managed to reduce my long acting insulin by 20 units. I have lost 6lbs so far I was astounded it came off in the first week. The only time I have had bad stomach pains is when I've eaten something bad and I get terrible runs 20 mins after eating, but once I've been to loo pain stops. I had vomiting once because I think I over ate a few days after taking it. I was super bloated and a few hours later I threw up then I felt fine again. So I just eat little and often, mostly grazing and picking at fruit. I was worried about taking this because of the comments I've read and with having IBS I didn't know if it would be bad for me. But I have no issues taking it and so far so good. Its still early days for me but I would 100% recommend it."

10 / 10
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  • Worried
  • Taken for 1 to 2 years
  • July 4, 2019

For Diabetes, Type 2 "When I started Ozempic dose of 0.25 I lost 10 pounds sugar levels dropped from 6.7 to 6.3. I experienced a hard time wanting to drink water and felt water logged after I drank water. Doc increased dose to 0.5 and 4 months ago started having diarrhea, sulphur burps, bloating, fatigue and more serious a lump on my right side of my throat and sore throat. My doc was surprised that I had these side effects a year later after taking the medicine. Ozempic is the only medication I'm take other than vitm D,B12, and calcium. My ultra sound shows several lumps some larger than others and now I'm waiting for the referral to see a nose, ear, throat specialist. Stop taking Ozempic 3 weeks ago.. Worried about the side effects of thyroid cancers..."

1 / 10
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  • Baldw...
  • March 4, 2020

For Diabetes, Type 2 "I currently take 1000 mg of Metformin twice a day, Lantus at night, and Humalog before I eat a meal and snacks. I started taking 0.25 mg of Ozempic on 01/03/2020. By the first evening, I was cramped up so bad, I didn’t want to eat or move. This really didn’t change for 3 weeks. At that time I called my Doctor and told her what I had experienced & then we moved to 0.5 mg. All I can tell you is that I have been miserable since starting to take this drug. Excessive gas in my stomach that leads to bloating, abdominal discomfort, and waking up every 1 or 2 hours to belch away the gas. OMG the smell of the gas from my stomach could wake the dead and that terrible taste I have in my mouth most of the time. I will find out about A1C in the coming weeks. I have been able to reduce my Lantus from 70 units to 40 units, and Humalog from 1 unit/5 carbs to 1 unit/10 carbs."

5 / 10
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40 Report
  • Bill
  • Taken for 1 to 6 months
  • November 7, 2019

For Diabetes, Type 2 "Ozempic is DANGEROUS!!! I started to get unbearable stomach pains, bloating, diarrhea, increased heart rate, increased blood pressure, and a host of other problems. It got to the point where if I really had to go to the bathroom, I almost couldn't hold my stool because it was frequent urgent diarrhea. I suffered through a nightmare. One day I went to visit NY and I forgot to take my shot of Ozempic. My symptoms ALL disappeared after a few days. OZEMPIC was the culprit. My blood pressure, heart rate and everything else went back to normal. I was so happy and felt great again. Doctors ARE NOT GOD. My doctor gave me the Ozempic even though he knew my insurance didn't cover it and it would cost over $550/month. He kept giving me the free samples so I wouldn't have to pay. What kind of doctor puts you on a long term med knowing you can never afford it? Bottom line is.... DO NOT TAKE THIS DRUG. YOU'LL REGRET IT."

1 / 10
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  • Displ...
  • Taken for less than 1 month
  • May 5, 2021

For Diabetes, Type 2 "I only did 2 lowest dose injections and stopped. The side effects were awful and still linger. The worst thing about the medication has been the gas, bloating, diarrhea and awful taste/smell when I burp. I’m 6 days in after my last injection and I still have all symptoms and continued diarrhea."

1 / 10
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  • Type...
  • Taken for 1 to 6 months
  • May 16, 2023

For Diabetes, Type 2 "I am on my 3rd month of taking Ozempic. No decrease in A1C as of yet. Weight loss, none. Ease of use, I find handling the needles cumbersome. The needles are smaller than Trulicity and less painful to inject. Less bruising at injection site. Current side effects: Nausea, stomach pain, stomach discomfort, swelling, bloating, increased constipation, increased hunger, sour stomach, headaches. I find I am forced to take additional medication/supplements in attempting to eliminate some of the side effects. I've taken stool softeners and laxatives in order to improve constipation with limited success. I am taking pain reliever almost daily for headaches. I am also taking medication to help ease the nausea with limited success."

1 / 10
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  • JCR
  • Taken for 6 months to 1 year
  • July 11, 2019

For Diabetes, Type 2 "I have type 2 diabetes and before Ozempic, my A1C was 6.3, now it's down to 5.3. I tried Trulicity before but it was a hassle with the one dose pen and refrigeration, and more expensive under my plan. Didn't help with my weight at all. Ozempic has worked great for me. Completely controls my appetite. It does cause some bloating and nausea, but not severe enough to make me need to stop taking the medication. I started on 0.25 and then increased to 0.5 - I've lost 27 lbs so far! I'm really hoping the appetite control lasts. I think with this drug, you really MUST decrease your food intake to lessen the side effects."

8 / 10
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  • Big...
  • Taken for less than 1 month
  • August 16, 2022

For Diabetes, Type 2 "Ended up in the emergency room on the day of the second dose. Triggered a gall bladder issue and ended up elevating my liver enzymes. Symptoms mimicked a heart attach of pancreatitis. Hard to tell the difference. Severe abdominal pain radiating to the back, elevated heart rate, nausea gas, bloating. For some people, this type of medication is very very bad medicine and totally not worth it. I lost 10 pounds in two weeks because it made me so sick I could not eat or drink. One day this will also have FDA black box label on it like Byetta. A class action lawsuit will be on your TV commercials. I would be seriously careful if you plan on taking this medication for anything, weight loss or glucose control. Not worth it. Once you get sick you will be longing to get the stuff out of your system and will be physiologically impacted by the experience. No antidote. Have to wait it out. Never again. The Russian roulette of diabetes medication. Taker beware."

1 / 10
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  • Never...
  • Taken for 1 to 6 months
  • July 10, 2019

For Diabetes, Type 2 "I've had similar experience while on Ozempic I lost 20lbs in 2 months but the vomiting, bloating got worse. I went to the ER on the 1st of July and just got home today. I was diagnosed with acute pancreatitis due to Ozempic. I think these companies need due more studies before prescribing this on us. We aren't lab rats."

1 / 10
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  • Hating...
  • Taken for less than 1 month
  • July 19, 2022

For Cardiovascular Risk Reduction "This is the worst medication I have ever had. Side effects of egg burps, vomiting, bloating so bad. DO NOT TAKE THIS. 30% of people that try this drug end up having problems with it. DO NOT TAKE. You can't eat, everything that goes into you makes you want to throw up. DON'T TAKE! Never ending Nausea and weakness. DON'T USE SAVE YOURSELF. Head aches....."

1 / 10
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  • No th...
  • Taken for 1 to 2 years
  • November 5, 2021

For Cardiovascular Risk Reduction "Started low dose .25, experienced discomfort in the stomach. Increased 4 weeks later to .5, symptoms got worse, blood sugar improved. Another 4 weeks after moved to 1mg dosage and life is awful. I've lost all control of my bowels from the severe long-lasting diarrhea, sometimes pooping the bed. I'm wearing adult diapers at 35 and my self esteem has taken a nose-dive. The sulfur burps are horrible and constant. The gas and bloating makes me look and feel horrible. I'm following a diet and doing every single thing my doctor has asked me to do for 7 months. I've lost 32 pounds but sleep in a diaper. Was it worth it? No.... Nope.... My A1C improved a tiny bit but otherwise I'm just feeling tired, weak and totally mortified. Can't go hardly anywhere unless I KNOW there is a restroom very close. Vomit every day."

1 / 10
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19 Report
  • Caused...
  • March 3, 2022

For Diabetes, Type 2 "I took .25 for about 6 months and thought this was a miracle drug. Caused slight constipation, but I dealt with it. When they increased me to .5 mg, I started violently vomiting the next day. No one could figure out what was wrong with me. Pancreatic enzymes were high, but not high enough to diagnose pancreatitis. I could barely eat for two months. Gas, bloating, side pain, back pain, stomatitis pain, non-stop burping, constipation, nausea, vomiting off and on. My food perpetually felt like it was backed up into my mouth. They had to take me off of the drug and now my sugars are higher than ever and no one can help me. They were ok before, but now doctors consider me as failing two types of drug classes because of this, won't give me my old meds back, and I may have to go on insulin. I am gaining weight like never before and am so tired that I can barely function. They now believe it gave me gastroparesis and I can't get better. I would recommend this medicine to no one."

1 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.