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Ozempic User Reviews & Ratings (Page 3)

Ozempic has an average rating of 6.7 out of 10 from a total of 1,563 reviews on Drugs.com. 52% of reviewers reported a positive experience, while 23% reported a negative experience.

Reviews for Ozempic

Commonly mentioned side effects
  • 9ru...
  • Taken for 1 to 6 months
  • September 10, 2022

For Cardiovascular Risk Reduction "Absolutely horrific. I get it works for most people, but unfortunately not me (and should not be promoted as a miracle drug that can help all obese people lose weight, as it doesn't work for everyone). I took 0.25 (the smallest dose) for 3 weeks and nothing (I yo-yoed with my weight; lost a bit then gained it again). After 3 weeks (not sure why 3 weeks for me), the main side effects kicked in. Diarrhea/loose stools, constipation, vomiting, nausea. Worst side effect was for 3 nights in a row, at about 3 a.m. I projectile vomited. First night I almost aspirated and choked on my own vomit trying to make it to the toilet without throwing up. Second night, even though I had the bathroom bin next to my bed, I was still projectile vomiting, and I couldn't sleep as I had a panic attack that I'd pass away overnight and my family would find me dead as I couldn't breathe as I had undigested food stuck in my esophagus. Gave up after 5 weeks of the lowest dose."

1 / 10
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  • Bis...
  • April 7, 2023

For Weight Loss (Obesity/Overweight) "I am going on week 11 with Ozempic, and have lost 24 pounds. I have had all 5 of the main side effects, nausea, stomach pain, vomiting, diarrhea, and constipation. I am happy with the weight loss, so am learning to manage these. By trial and error, I've found that I can't eat much at one time (don't really want to), need to avoid fatty foods, drink lots of fluids, and take Senna laxative every night for the constipation, and keep Zofran around to help with nausea. Yes, these first few weeks have been difficult, but the weight loss is worth it to me. Plus, the side effects get less the longer I'm on Ozempic. I am currently on 1.0 mg and think that's quite enough. I am rarely hungry and often have to make myself eat. I hope to lose 65 pounds total."

8 / 10
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  • All...
  • Taken for 1 to 6 months
  • March 21, 2023

For Weight Loss (Obesity/Overweight) "On December 19, 2022, I saw my medical provider and requested a prescription for Ozempic. She agreed that at 5’3” and weighing 192 lbs, it would be a good option for me. I started Ozempic on January 3, 2023. The first time I weighed myself after starting Ozempic was at the beginning of February, and I weighed 179 lbs. Through February, my weight bounced between 181-175, then I lost another 5 lbs in the first two weeks of March. I’m hoping to reach 160 by mid-April. My weight goal is 130-135. I am very happy with Ozempic’s effect on my weight loss. I have had assorted side effects. I had two days of extreme headaches after my first dose, but I’ve only had mild headaches with dosage increases since. My stomach is mild to moderately upset most of the time, and most of the time I don’t have much appetite. I’m at a 1 mg/week dosage now, and I’ve started having a lot of bad-tasting burps, but constipation is by far my worst side effect. I don’t know if I would have bowel movements without laxatives."

9 / 10
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Frequently asked questions

  • Eri...
  • Taken for 1 to 6 months
  • June 17, 2023

For Weight Loss (Obesity/Overweight) "I am a 45-year-old woman. Started Ozempic .25 mg dose 6 weeks ago, increasing to the .5 mg dose after 4 weeks. Lost 13 pounds so far, which makes me happy. Started with some nausea, some explosive diarrhea, and a general fullness feeling, and no cravings. Now I’m experiencing more constipation, and after the last injection, a dizziness/lightheaded feeling. Don’t like that at all. It never goes away. Don’t know if it’s related, but also tingling and some numbness in one foot. I’ll try injecting my thigh next time and see if that helps the dizziness because I definitely do not enjoy that feeling. Almost a jittery feeling as well. Weird. So I’m hoping these will improve over time as I am liking the weight loss results so far. I’m wondering if anyone else has had this dizzy/jittery feeling and if it will go away."

7 / 10
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  • Dro...
  • Taken for 6 months to 1 year
  • April 2, 2025

For Type 2 Diabetes "I've lost about 40 lbs since starting Ozempic 11 months ago. My A1C is now within normal limits, but I still take Metformin. My non-alcohol fatty liver disease has resolved as well. I experienced nausea and vomiting early on in treatment, but that has mostly resolved. I feel hunger less and feel full longer. Constipation is a big problem, so I use an occasional stool softener or eat some prunes to keep things moving. The medication decreases the pleasure I get from food, which is weird sometimes. When I go out of town, I used to look forward to trying a new restaurant, but now it's just 'meh' no matter what I eat. I found that I have more nausea if I inject in the abdomen, so I do it in my arm or thigh instead."

8 / 10
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  • Kat...
  • Taken for 1 to 6 months
  • April 14, 2023

For Weight Loss (Obesity/Overweight) "Started Ozempic just over a month ago (0.25 mg). Needing to lose about 33 lbs. Had some constipation for the first 3 weeks, which has just subsided. Tired some days. Just had my first shot of 0.5 mg. Have lost almost 10 lbs. Happy so far."

10 / 10
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  • jaz...
  • Taken for 1 to 6 months
  • November 15, 2019

For Type 2 Diabetes "UPDATE: I've been on Ozempic for 6 weeks now. I didn't have any of the major symptoms listed by many, but in my 5th week, I noticed I haven't been able to pass stool as frequently as I normally do. Yes, I was constipated in the 4th and 5th week. I stopped taking Ozempic, and I was normal again. I like this medicine shot except for the constipation part. I did lose some weight over it and inches, which was a big plus. I wish I could keep taking Ozempic, minus the side effect."

8 / 10
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More FAQ

  • Foo...
  • Taken for 1 to 6 months
  • August 30, 2021

For Cardiovascular Risk Reduction "I'm in week 6, and I have lost 15 pounds!!!!! Total miracle. I started out at the .25 dose for a month and last week began .5. I have absolutely no appetite. Very easy to stick to a healthy diet. Predominantly low carb but do allow some complex carbs here and there. I eat very small meals--I am full very quickly. I am a little nauseous in the morning, slight constipation, which easily was alleviated with taking daily probiotics, and after going out to dinner the other night and eating what I thought was a small meal, had really bad acid reflux. The food was spicy, and although I didn't eat a lot of it, I ate later than usual. I will never do that again. I fortunately have not had any of the other side effects others mention. I want to lose another 70 pounds, so I am hoping that at the 1 mg dose I can accomplish this. I would think the weight loss will slow at some point. I remain a little nervous about increasing the dose, although I had no ill side effects when last increased."

10 / 10
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  • Anonymous
  • August 13, 2021

For Cardiovascular Risk Reduction "Was prescribed Ozempic for weight loss because of being insulin resistant and not being able to lose weight (I'm 50 lbs overweight for my height) after a hysterectomy despite working out 5 days a week and eating healthier. I'm on week 3 of a 0.25 dosage, and I'm finally losing weight, 5 pounds so far! No side effects except that I did have some constipation for about a week, but now I'm back to being regular with more water consumption. It did significantly cut back my craving for sweets, however, it didn't completely get rid of it. I noticed my hunger isn't as intense as it used to be. This medication was a last resort for me because I was having no success losing any weight regardless of my consistent efforts with traditional methods for weight loss, which was pretty upsetting. I continue to diet and exercise with this medication, and it has been a great addition to a healthier lifestyle for me!"

10 / 10
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  • Car...
  • Taken for 1 to 6 months
  • May 31, 2019

For Type 2 Diabetes "Taking Ozempic for insulin resistance type A and PCOS. Took 0.25 for the first 4 weeks. Side effects included: severe nausea and flu-like symptoms. Constipation is still a problem. Mild nausea when I upped the dose to 0.50, but taking a generic store-brand nausea medication has helped a lot. Appetite greatly reduced, and I find smaller meals and snacking more frequently throughout the day to be very helpful. My side effects only lasted 1.5 weeks and have not returned with increased dosage. Started at 193 lbs and down to 186.8 lbs in only 1 month. Will continue to take!"

8 / 10
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  • Suc...
  • Taken for 1 to 6 months
  • July 26, 2022

For Cardiovascular Risk Reduction "I've been on Ozempic for 4 months. My doctor tiered the dosage from 0.25 mg for 4 weeks, then 0.50 mg for 4 weeks, then increased to 1 mg for the remaining time. I've just gone in for a check-up and increased to the 2 mg dose beginning this week. Each dose, I experienced some stomach knots, but they resolved after the first day of the adjustment. I did initially have some very mild nausea, but all I needed to do was take a sip of cold water to take care of it. I stress, the nausea was very, very mild. I do have a bit of constipation, but I balance with stool softeners and strict keto (high fat). I've lost 21 pounds to this point, and this medication is the first thing that's controlled my appetite. I used to feel hungry all the time, but now I don't feel like I need to eat all the time. I don't snack all the time like I used to. I was doing everything I was supposed to, I was working out and strict keto. But I was stuck and couldn't lose any more weight. I've gone from 203 to 181."

9 / 10
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  • Sic...
  • Taken for 1 to 6 months
  • August 13, 2019

"I’ve been on Ozempic since May to help with weight loss. Started with 0.25 and now am up to 1 mg. The nausea has been fearless. The constipation is unreal. I’ve ended up with major hemorrhoids. I’m always tired. I have lost 14 lbs, but these side effects are ruining my life. This is not worth it."

1 / 10
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  • Sas...
  • Taken for 1 to 6 months
  • June 26, 2019

For Type 2 Diabetes "Been on this for 5 weeks now. Levels are finally starting to stabilize, and I feel more like a human. The nausea has been horrendous, the weight is falling off, 10 lbs so far. Can't overeat or the nausea gets worse, and I throw up. Abdominal cramps were bad week 2 & 3 but are less frequent and not bad too often. Constipation has been hard for sure, I have to take something to help me go. Just increased from .25 to .50 five days ago, and the nausea is hitting me more frequently again. Tums, a fan on near my face, and nausea suckers are so helpful. The side effects can be pretty severe, but I gotta keep trying to push past it. Good luck if you take this."

9 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • August 31, 2022

For Type 2 Diabetes "I did not have a good experience with Ozempic. Other than a 35 lb weight loss in 4 months, there is nothing else good I can say about it. From the first dose, I’ve had nausea and dizziness. The second dose has been a rollercoaster of constipation, stomach pain, fatigue, with continued nausea and dizziness. I’m constantly sick, I can’t eat anything more than a couple of bites of food. Nothing tastes the same, and the smell of food makes me head to the bathroom with nausea. So going out to eat is only a memory now. I do not recommend this medication. This cannot be healthy for anyone. I’ve stopped taking the Ozempic and am wondering if these side effects will end, they say it takes 5 weeks to leave your system. I’m counting the days!!"

1 / 10
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  • LuL...
  • Taken for 1 to 6 months
  • August 8, 2019

For Type 2 Diabetes "I started Ozempic on June 6, 2019 (weighing 190 lbs) at .50 dose and was very nauseous and ended up throwing up and felt extremely sick all week. The next week I lowered it to .25 and stayed at that dose through July. I bumped it back to .50 and the nausea has been better and controlled with Zofran and Dramamine, but the constipation has been horrible. I can only seem to use the restroom via an enema. I have lost weight, currently at 157 lbs, so it has all been worth it to me. I am taking an RX to help with the constipation now and plan to continue the shot until my next Dr's visit in September; we'll see from there."

8 / 10
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  • D J...
  • Taken for 1 to 6 months
  • March 29, 2019

For Type 2 Diabetes "I am on week 6. First 4 doses at .25, and now the second week of .5. I've had the constipation but have learned to just take a laxative once a day with my metformin. This drug brought my sugar down from the 600s to the 90s in 5 weeks. I had an A1C of 17.1, I'm now down to a 9 and can't wait for my next reading. Yes, the cramping and gas have been bad at times, but I'm hoping it mellows out. But for me, it has saved my life more than likely."

9 / 10
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  • Ano...
  • May 23, 2025

For Chronic Kidney Disease "Took .25 for 4 weeks, now on week 3 of .5. Hardly eating, feel full all the time. A lot of burning, hiccups during the night, general tired feeling, losing some weight, some constipation. Supposedly will get balance at 12 weeks. Will see. So far, not comfortable. Pharmacist recommended Prilosec for gas, hiccups, etc."

5 / 10
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  • Joe...
  • Taken for 1 to 6 months
  • July 5, 2021

For Cardiovascular Risk Reduction "Started on .25 and now onto .5 for the next 4 weeks. My side effects have been mild nausea, a lot of constipation, slight anxiety, mild diarrhea, mild tummy ache, intermittent tiredness, and feeling somewhat under the weather. There is no pattern, it’s random. I do think it’s the medication, as prior to this, I had none of these symptoms. It is not great, but tolerable. I think the meds are really kicking in now. If I have a small snack, the nausea subsides. I have little to no appetite, probably consume 1000 calories a day. And my mind is not consumed with food, and before I had an obsession with food. For me, it’s been life-changing. I put on 15 kg during Covid lockdown. Was 85 kg, now 81 kg."

10 / 10
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  • Dra...
  • Taken for 1 to 6 months
  • February 21, 2024

For Cardiovascular Risk Reduction "I also have type 2 diabetes and take Jardiance. I was very unsure if I wanted to take this drug or not because of all the possible side effects. I have been on it now for over a month and have been very lucky that the side effects have been minimal. For the first couple of weeks, I had a little fatigue, mild headache, and a little constipation, but taking magnesium nightly has helped with that. As long as I eat healthy and small portions, all is great. My brain is no longer obsessed with eating, and worrying about what my next unhealthy snack is going to be. All my sugar cravings are gone, and blood sugars are at a 5. In the last 5 weeks, I have lost 13 lbs. I started at 0.25mg and am now at 0.5mg. I do the injection in my stomach, as it is totally painless there. It is not covered by my insurance and is on the pricey side, $266.00 Canadian, every six weeks, but it works for me, so I will continue taking it."

10 / 10
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  • Cej...
  • December 15, 2019

For Type 2 Diabetes "I’ve always had a BMI of around 23-25, but menopause saw my appetite skyrocket, and it went to 26. I’m 5'5" and my weight went up to 166 pounds on a slight frame. My private doctor in the UK started me on Ozempic for weight loss. It cost £120 a month (sorry USA folks, but you pay way too much for your drugs!), and after a month on 0.25, I’m now on 0.5. I don’t want wine or sweet things noticeably, and I’ve lost about 4 lbs, but now I’m on a higher dose, this is accelerating. I feel like the old me in terms of being able to control my food, which is great! Side effects are occasional nausea and near-constant acid reflux, but I can control this with Rennie right now, and also constipation, unless I drink a lot of water. It’s really worked for me to prevent a slide into obesity."

7 / 10
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  • Oz1...
  • Taken for 1 to 6 months
  • May 15, 2022

For Cardiovascular Risk Reduction "I've been taking Ozempic since January 2022 for weight loss. I started out with a 0.25 mg weekly injection, which was increased to a 0.5 mg weekly injection after the first pen. To date, four months later, I've lost 33 pounds, down to 265 pounds from 298 pounds. My appetite is significantly reduced, and I've implemented healthy diet changes with the help of the weight loss clinic where I'm a patient. Recently, I began experiencing constipation, which is a known side effect. My physician recommended Miralax to combat the constipation."

10 / 10
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  • The...
  • Taken for 1 to 6 months
  • June 6, 2023

For Weight Loss (Obesity/Overweight) "I have been using it for about 1 1/2 months and have lost 14 pounds. I don't have much of an appetite, but some of the other side effects are bloating, constipation, diarrhea, throwing up, and feeling very tired. I love the weight loss, but the side effects are too much!"

7 / 10
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  • MJa...
  • Taken for 6 months to 1 year
  • January 18, 2021

For Type 2 Diabetes "I was on Ozempic (0.5) for 11 months. I had all of the worst gastric symptoms the entire time. Constant diarrhea, constipation, sulfur burps, constant rumbling stomach, VERY loud and odoriferous flatulence, and no real control over bowel movements. I was wearing diapers so I could sleep because I was afraid I would not have time to get to the bathroom. My A1c went from 16+ to 6.6 in 3 months, so I stuck with it. However, I had lost 70 lb. before I started it - and gained back 40! I eat right and did exercise (until the gastric situation was too bad). It has taken 6 weeks, and I finally feel normal, but my A1c has shot up to 13 in that time (which means it's probably higher than that). I don't have any other chronic illness besides diabetes - no gastric issues before that."

7 / 10
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  • Bea...
  • October 14, 2019

For Type 2 Diabetes "I started Ozempic at the end of July 2019. After 10 years of Metformin 1000 mg a.m. and p.m. & Januvia, the result turned into explosive diarrhea. Tried Jardiance, which resulted in yeast infections. Then Janumet, all of these with Metformin. Constipation. Started Ozempic in July, 0.5 mg with Metformin. Lost weight and appetite suppressed, but diarrhea continued. Changed to 1000 mg Metformin in a.m. & Januvia in p.m. Constipation again. Changed to 1 mg Ozempic after several months and 1000 mg Metformin in a.m. and 500 mg p.m., no Januvia. Constipation. Finally taking 1 mg Ozempic and 750 mg Metformin a.m. and p.m. works great. Bowel movements normal. My daily readings went down using Ozempic. No side effects. Lost 19 lbs. Not due for A1C until December. Love it. Went from 200 lbs to 181. Sugar cravings decreased. Feel positive. I am an active 70-year-old female. I don’t plan on taking Ozempic forever because the possible long-term thyroid side effects scare me."

10 / 10
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  • ACD...
  • Taken for 1 to 6 months
  • May 27, 2023

For Weight Loss (Obesity/Overweight) "I have experienced severe gas, belching, flatulence, moderate nausea all night, not heartburn but feels like seasickness, and moderate constipation. Have had about a 7-pound weight loss in a month. Simple to use with no problems injecting or at the injection site."

3 / 10
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