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Semaglutide for Weight Loss (Obesity/Overweight) User Reviews (Page 5)

Brand names: Ozempic, Wegovy, Rybelsus

Semaglutide has an average rating of 7.3 out of 10 from a total of 613 reviews for the treatment of Weight Loss (Obesity/Overweight). 63% of reviewers reported a positive experience, while 19% reported a negative experience.

Reviews for Semaglutide

  • Dee
  • Taken for 1 to 6 months
  • April 10, 2023

Wegovy (semaglutide) "I wish I did more research before starting this. I started on Saxenda and worked up to 3.0 mg, the max dose. I had a few bouts of severe diarrhea and vomiting. I lost a total of 15 pounds and then started getting ravenous. Then I got switched to Wegovy 2.0 mg and then moved up to 2.4 mg. Only had a couple of incidences of terrible nausea, usually when I ate greasy, heavy, or fried foods. But generally, I feel like crap every day. Once on the Wegovy the weight literally fell off. Mostly because I just didn't think about eating anything, or my appetite would be satisfied with a very small portion of food. The biggest side effect is skin irritation; like a constant sunburn. Clothes touching my skin bother me. Or riding in a car and bouncing. It became intolerable. And chills, makes my skin ache. I easily surpassed my goal weight and now trying to decide if I want to quit it altogether or reduce the dosage and hope the skin irritation goes away."

3 / 10
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  • Jjinla
  • April 2, 2023

Wegovy (semaglutide) "Awful. I felt tired and like I had morning sickness the whole time. Was on one month of .25 mg and two months on .5 mg. It never got better. I was constipated and on the verge of throwing up constantly. Also started post-menopausal bleeding despite being on HRT. All of this, and I only lost a whopping 9 pounds despite barely being able to eat even cereal. Your diet turns to garbage because you just stick to stuff that won’t make you feel more nauseous. You will not learn how to eat properly; just how not to eat foods that make you throw up. I just switched to phentermine, and I’ve already lost two pounds in 5 days. My energy is back. Zero side effects and less than $15/month. Read the long-term reviews, people. Unless you are going to stay on this for life, which I would never do seeing how it messed with my hormones, you will 100% gain it all back and then some."

3 / 10
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  • Vee
  • Taken for 1 to 6 months
  • March 25, 2023

"Totally took away my appetite. I no longer eat breakfast or crave certain foods/snacks. Gave some foods a "metallic" taste. Makes me feel fuller. I had no side effects."

3 / 10
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Frequently asked questions

  • Tough...
  • Taken for less than 1 month
  • March 14, 2023

Wegovy (semaglutide) "I am on my 3rd 0.25 dose of Wegovy. I feel terrible most of the time. I have lost 5 lbs and am definitely not hungry due to nausea. My prescriber will not prescribe Zofran with Wegovy, because she feels nausea that severe should be considered a negative side-effect and the medication stopped. That's reasonable. I read the reviews before I began the med and take Omeprazole daily, as well as MirraLax. I am 57, menopausal and used to feel really good most of the time. Sadly, this med is not worth the side effects for me. I really, really wanted to tough it out but as a nurse, I feel it's creating problems that I did not have before taking this medication. The nausea is constant, the belching/burping is so frequent that its embarrassing, stools are like a rock, and the worst feeling of chest tightness. I had so hoped I would be one of those without adverse side effects but I am not."

3 / 10
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  • Teresa...
  • Taken for 1 to 6 months
  • March 12, 2023

Ozempic (semaglutide) "After two doses of .05 mg, I started having shortness of breath. So bad that I wasn’t able to do anything with exertion involved. While grocery shopping I almost passed out.Although I have lost 16 lbs. I am going to stop taking the medication."

3 / 10
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Are you taking this medicine?

  • Mel
  • Taken for less than 1 month
  • March 9, 2023

Wegovy (semaglutide) "week 2: I have not had any appetite suppression, just very bad constipation. I've had to take stool softeners with every meal and use glycerin suppositories to unplug my colon. No weight loss yet."

3 / 10
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  • Miche...
  • Taken for less than 1 month
  • November 11, 2022

Wegovy (semaglutide) "Horrible! Spent 24 hours in ER with severe nausea and vomiting! Needless to say, I have 3 doses left if anyone needs!"

3 / 10
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More FAQ

  • Vanessa...
  • August 4, 2022

Wegovy (semaglutide) "Expensive and worthless. I got extremely nauseous for days unable to eat and felt like I’d collapse from weakness but I had no appetite."

3 / 10
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  • Cari
  • Taken for less than 1 month
  • July 25, 2022

Wegovy (semaglutide) "I am on my second week. First week (day after shot) I got severe nauseous and dry heaving. I was so exhausted and zero energy. My depression got way worse. Second week the same. I don’t think I will continue but I signed a contract and I was told I can cancel at any time but it looks like this is going to be a problem. This has been a wake up call and the nausea has taught me a lesson to never eat bad foods again and really focus on portion control. The side effects aren’t worth any weight loss in my opinion!"

3 / 10
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  • Hair...
  • May 12, 2022

Wegovy (semaglutide) "Helped me lose weight. But the hair loss was extreme. I only needed to lose 15 pounds to get to my goal. But I had the extreme hair loss. I had tests done and hormones and thyroid profile all normal, there was no other explanation. Hope it grows back."

3 / 10
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  • Why...
  • Taken for 1 to 6 months
  • April 10, 2022

Wegovy (semaglutide) "I tired the 0.25 dose and experienced constipation. The next month my doctor prescribed 0.5. not only did the constipation continue, there was horrible burping, severe indigestion that caused me to take a day off work. After that, I didn't eat much just drank water, peppermint tea, smoothies. In addition to the those side effects there's also the possibility of life threatening side effects. While it was easy to administer, I'd rather stay fat than endure the pain of side effects nor additional medical issues to increase weight loss"

3 / 10
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  • Jan
  • Taken for 1 to 6 months
  • February 8, 2022

Wegovy (semaglutide) "I am on week 6, .5. So far, it has not done much other than a little heart burn and extra gas. Have not lost weight and actually gained a few pounds, has not curbed my appetite so to be fair I have been eating more than I should because of my appetite still there. Hanging in there and hopefully I will see a change going forward. The side effects have not been enough to make me give up."

3 / 10
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  • Kareb...
  • Taken for 1 to 6 months
  • February 2, 2022

Wegovy (semaglutide) "It works amazingly well but the actual and physical cost was too much for me to continue. Been on it since August and I've lost 40 pounds. That's really easy to do when you're starving due to constant nausea and vomiting. Though I'm terrified of gaining the weight back as others described, I had to stop taking it as I was so sick everyday and exhausted. I'm fighting it but my appetite has already returned with a vengeance. That's not surprising considering I've been malnourished for months."

3 / 10
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  • Lisa
  • Taken for 1 to 6 months
  • January 29, 2022

Wegovy (semaglutide) "I started Wegovy 8 weeks ago. Coupon made it 25 a month. On the dose .25 I had nausea and occasional diarrhea. On my 7th injection dose .5 I got very sick, extreme nausea, diarrhea and stomach pains. Skipped my next dose. Have been to the emergency twice for fluids and anti nausea medicine. The diarrhea is the worse of it non stop. I can not keep any thing down. I am down 23 pounds but feel miserable. I hope the medication wears off soon. I do not recommend the medication makes you feel so sick."

3 / 10
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  • Han
  • Taken for less than 1 month
  • June 10, 2024

Wegovy (semaglutide) "I have been on 0.25 of Wegovy for 2 weeks. No appetite change, feel fuller slightly sooner. No side effects but also no weight loss. I have been eating right and I am a cleaner, so I am moving around all day. Disappointed really considering how much it costs! Expected at least 3-4 lbs off. Switching to Monjaro today, which is a higher dose!"

4 / 10
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  • Kris
  • Taken for less than 1 month
  • July 2, 2023

Ozempic (semaglutide) "This drug affects everyone differently, but for me, the side effects were too bad, and I had to stop after 2 weeks. It totally worked by killing my appetite and making me feel full, and after the first week, there were days I didn't even want to eat at all. I lost about 8 pounds in two weeks, which is great. However, during the 2nd week, I got the worst upset stomach of my life and almost went to the ER. I had intense diarrhea for an entire day, along with nausea, the chills, a swollen stomach, and then sweating. I had to take a sick day from work because I was also dizzy, and my heart was racing. It finally subsided about a day and a half, but it scared me so badly that I stopped taking the drug. Now I understand why it has a black box warning. I'm happy for the people who can use this without bad side effects. For me, I have a young child and demanding job. I can't go around with symptoms of food poisoning and try to act like I’m ok."

4 / 10
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  • Pat...
  • Taken for 1 to 6 months
  • June 22, 2023

Ozempic (semaglutide) "I tested borderline diabetic and am overweight, so I was prescribed .5 mg Ozempic once per week. I started it six weeks ago and have lost about 3% of my body weight. I have been eating less and more healthfully, but haven't been as active as I'd like. Right within 12 hours of my first dose I felt nauseous, tired, and just plain sick. Constipated. I was hoping the side effects would go away, they haven't. I can pretty much write off the two days after a dose because I feel so ill and very tired. It has taught me not to eat too late before bed because I get severe reflux and usually make myself vomit. I wish it worked, but for me I think it's a no. I'm weaning myself off, injecting .25 mg until I've used all the Ozempic."

4 / 10
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  • Odie
  • Taken for less than 1 month
  • May 22, 2023

Ozempic (semaglutide) "This is my third week and I feel absolutely horrid!! I have constant dizziness, extreme fatigue, and generally feel like crap. I don't think I will continue. It's not worth it to lose maybe 20 lbs but can't get out of bed and function. I am tired of feeling like death warmed over. Unfortunately, because it is controlling my appetite I'm full after a few bites. I am on a 25 mg dose."

4 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • May 22, 2023

Wegovy (semaglutide) "I am experiencing extreme insomnia and tiredness. I am not sure if I will continue taking it."

4 / 10
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  • Costly...
  • Taken for 1 to 6 months
  • May 18, 2023

"I have been taking Wegovy since January, at first I lost 10 lbs on 0.5 mg. The doctor kept me at this same dose and I have not lost anymore weight. Never got nausea or any other side effects. The one positive is I don't crave candy as much as I have before. The bad thing is I have actually gained 5 lbs back. I'm unsure if it is due to remaining at the same dosage for 4 months now or if this just doesn't work for me. Getting too expensive so I'm thinking to just stopping the program."

4 / 10
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  • Cari...
  • Taken for 1 to 6 months
  • April 24, 2023

Wegovy (semaglutide) "I am on week 4 of Wegovy, the first 2 doses were 0.25mg. The last 2 were .5mg. I've had stomach pains and nausea to the point I'm in tears it aches so much. My weight is going from 221 lbs to 215 lbs, I'm 5'9". I hardly eat for fear of worsening stomach issues. While my pharmacist says the side effects should go away by now, they haven't. I also have no energy, want to sleep, and have a hard time getting my blood sugar above 98, that's after a healthy meal with protein and a vegetable. Not sure this is worth it."

4 / 10
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  • Chemmom
  • Taken for 1 to 6 months
  • April 20, 2023

Wegovy (semaglutide) "I lost 15 lbs on my own then joined a diet program and lost another 40 lbs. I plateaued for 6 months then saw a weight loss doctor who put me on Saxenda (the daily injection) since Wegovy was not available. In 10 weeks I lost 6 lbs. I never felt this fullness people have talked about. When Wegovy became available was started at the second highest dose and felt great the first week, but then got severe heartburn and nausea. At the highest dose my side effects disappeared. During the 24 weeks I was on Wegovy I really never had a full feeling. I lost 4 lbs in that period. I decided to stop since I did not get my insurance to approve my refill in time. I have gained back some of the weight even though I am eating the same number of calories and still exercising 300 min/wk. I am still gaining my 10 lb loss back."

4 / 10
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  • slward
  • Taken for 1 to 6 months
  • April 17, 2023

"Although the medication does work, the side effects never stopped. Indigestion, belching soured eggs, bloating, and eventually diarrhea. The doctor said to push it out 10 days, all that did was reset the side effects after they'd finally stopped. I tried pushing past it and eventually stopped at .50mg simply because of the atrocious side effects that never lessened."

4 / 10
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  • Quad...
  • Taken for 1 to 6 months
  • April 9, 2023

Wegovy (semaglutide) "In am 75 years old. My starting weight was 207. I had 4 weeks of 0.25 mg, 4 weeks of 0.50 mg, and one week of 0.75. I now weigh 197. I have restricted my caloric intake and exercised, and have had only minimal side effects. Ten pounds in nine weeks is not much. Twenty years ago, I lost 38 pounds in 17 weeks using the Adkins diet. The cost was $1614 for four weeks at Costco. I switched to a men's clinic and now get Semaglutide using a syringe instead of a pen. The cost is $1888 for 24 weeks. I will continue (I have already purchased the 24 weeks plan), but I am disappointed."

4 / 10
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  • Marti...
  • Taken for less than 1 month
  • March 26, 2023

Wegovy (semaglutide) "Just started 2 days ago and am afraid to continue. Flu-like, headache, depression and anxiety ramped up. Feel foggy and not wanting to get out of bed."

4 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.