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Semaglutide for Weight Loss (Obesity/Overweight) User Reviews (Page 4)

Brand names: Ozempic, Wegovy, Rybelsus

Semaglutide has an average rating of 7.3 out of 10 from a total of 613 reviews for the treatment of Weight Loss (Obesity/Overweight). 63% of reviewers reported a positive experience, while 19% reported a negative experience.

Reviews for Semaglutide

  • Anonymous
  • Taken for 1 to 6 months
  • June 2, 2023

Wegovy (semaglutide) "I started at 173 lbs and have taken the third injection of the second pack dosage. My weight today is 168 lbs. I have not had any of the side effects. It has not controlled my hunger. I hope I will see a difference when I start the third packet dosage next week."

2 / 10
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  • Ally
  • Taken for less than 1 month
  • May 19, 2023

"I have lost 25 pounds on my own in the last 3 months and decided to give compounded semaglutide injections by my doctor a try to give me a helping hand. On 5/16/23 at 9 am I had my first injection in my arm. and I instantly got a slight headache. By 2 pm I was severely nauseated and had to leave work early. Stayed that way all night and my mouth was watering so bad I was standing over my sink for hours. My stomach was bloated and stayed that way for the next day. On days 2-4 food smelled so bad it made me nauseated. I didn't eat anything but toast. Nothing carbonated could be tolerated at all or sweet or cooked for that matter. But the worst part was the nonstop diarrhea and severe stomach cramps. I won't be taking this again. Ex-Lax is a lot cheaper!!! I hope this wears off soon. Not for me. Kudos to those who have no side effects or could stick it out. I can see why this has been so effective for weight loss (food looks and smells disgusting) but the sickness is unbearable to continue and I can't miss any more work."

2 / 10
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  • Kay
  • Taken for 1 to 6 months
  • May 18, 2023

Wegovy (semaglutide) "I’ve been on Wegovy for 3 months and have gained 2 lbs. I have had side effects such as severe constipation, fatigue and issues with my menstrual cycle. I am glad other people have had positive experiences with this drug, but It’s definitely no miracle. I decided I can make healthy changes without this medication. I stopped using it."

2 / 10
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Frequently asked questions

  • JDF
  • Taken for 1 to 6 months
  • May 13, 2023

Wegovy (semaglutide) "I started on the .25 mg then increased to .5 mg and now on 1.7 mg. So far I have not lost any weight and have been queasy almost the entire time. I have been using the relief band to help with the queasiness. I do not eat as much as I did before I started plus I don’t drink alcohol hardly at all now. Besides that… I am not sure of the benefits yet. I will try it for another dose increase to see if it works. If it doesn’t I am going to stop taking it."

2 / 10
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  • Summer
  • Taken for less than 1 month
  • May 11, 2023

Ozempic (semaglutide) "Never again! I have been taking this for 4 weeks now along with 3 family members and we all say the same thing. We feel exhausted. I’ve never felt so tired in my life. My son who’s so fit but has always struggled with his weight but runs several miles a day is struggling with tiredness too. If I take it on a Sunday and by Wednesday I could sleep standing up. Be warned."

2 / 10
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Are you taking this medicine?

  • Bpm
  • Taken for less than 1 month
  • April 22, 2023

Wegovy (semaglutide) "After being on another weight loss drug for 6 months and losing 35 lbs. My PCP and I decided to try Wegovy. I am currently on 0.25mg and on my fifth day. After the third day, I have been experiencing gas and diarrhea. Nothing that can’t be handled, in fact, it has started to subside. My only concern is that it doesn’t seem to curb my appetite. I had bariatric surgery in 2015 so I don’t have a huge appetite, but am worried that the current dose of .25mg of Wegovy that I am currently on is not working. I am hoping it will take a few days to kick in."

2 / 10
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  • Not...
  • Taken for 1 to 6 months
  • April 4, 2023

Ozempic (semaglutide) "I've been on Ozempic for 4 months. Recently raised my dose to .75 mg but I am stopping this medication. Yes, I lost 15 lbs but suffered with the worse sulfur gas, was sick in bed at times, missing appointments because I felt that crap. Yes, it makes you eat way less, I was never hungry but made myself eat because I had to. It gave me constipation, so had to take stool softeners and increase fiber. Now that I stopped- I get diarrhea two days later. This medication sucks for me anyway....and from the sounds of it, many other people also. Beware!"

2 / 10
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More FAQ

  • Ella
  • Taken for 1 to 6 months
  • March 30, 2023

Wegovy (semaglutide) "No widget loss no appetite loS after 5 weeks .. disappointed"

2 / 10
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  • FMC
  • Taken for less than 1 month
  • March 27, 2023

Wegovy (semaglutide) "I’ll be taking my third injection in a moment. I honestly feel like it’s not doing anything for me, but I don’t know if it takes time so one trying to at least allow it to produce results through the four-pack of shots I have. Halfway through though, not impressed at all. Very disappointed."

2 / 10
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  • Velma
  • Taken for 1 to 6 months
  • February 23, 2023

"Started in December 2022 and on a compounded version and to date have lost maybe 5 lbs. It's hard to tell as I am constantly bloated, constipated, and have gas pains and terrible heartburn, nausea and feel really tired. I have experienced these side effects from the first .05 dose up to the 2.4 that I am on now. I am weaning myself off of it as it is not beneficial to me."

2 / 10
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  • Toni_45
  • Taken for 1 to 6 months
  • December 22, 2022

"I am on week 9 which is the 1.0 unit dosage. I'm disappointed for multiple reasons. I've been EXTREMELY constipated which is a horrible feeling. I've taken apple cider vinegar, Mag 07, and Miralax but afterwards constipation returns. I've been gassy, bloated, and have not lost a single pound keeping in mind I workout 1-3 times a week. I have also experienced backaches, headaches, and a little nausea. I don't think the side effects are worth it since results can clearly vary since I haven't had any success. I'm not going to continue with the medication anymore."

2 / 10
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  • Sarah
  • Taken for less than 1 month
  • April 10, 2022

Wegovy (semaglutide) "Made me terribly sick. Took only 0.25 dosage one time, had terrible diarrhea, extreme exhaustion and some nausea. Definitely not taking the second dose. Not worth the pain. Did not loose any weight either. It stops you from eating because it makes you feel so bad if you do it. I also think this drug is meant for someone who doesn’t live an active life style. I work out all the time, I eat healthy and really just wanted to drop 15 lbs. This drug was very disappointing"

2 / 10
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  • Anonymous
  • March 26, 2022

Wegovy (semaglutide) "I have been on Wegovy for a little more than 3 months. Have lost only about 6 lbs. I exercise almost every day and have cut out a lot of unhealthier foods I am so frustrated."

2 / 10
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  • Helen
  • Taken for 1 to 6 months
  • July 2, 2024

Wegovy (semaglutide) "Started with 0.25mg, very easy, full instructions, separate pens for each dose increment, so foolproof. The nausea started within a couple of hours of the first injection, over the first month the nausea was pretty constant all day but eased off after around 5 days so 2 days with minimum nausea, however within 1 hour of 0.5mg dose nausea was worse and no let up, was actually sick on 1 day and felt like I would be sick in the second week. After 2 weeks on 0.5mg decided I could not continue to feel unwell ongoing. Weight loss was minimal, less than 1lb per week with 'careful' eating choices although not fully dieting but think you have to be very determined to tolerate the nausea."

3 / 10
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  • Brfr
  • Taken for 1 to 6 months
  • July 17, 2023

Wegovy (semaglutide) "Taking for BMI over 32%, weight reduction. Started weighing 220 lbs. Currently at 1.7 mg dose, with 2 weeks remaining. Since starting, I have lost 20 lbs. However, I will be discontinuing Wegovy due to the intolerable side effects. Ended up in the ER for vomiting, diarrhea, and flu-like symptoms. They gave me fluids, anti-nausea and cramping meds. That was around 24 hours ago and while I can keep liquids and soup down initially, I end up vomiting then uncontrollably retching hours later. It's been near impossible to eat healthy or at all, with a lack of appetite and a sudden aversion to the smell and taste of certain foods. I regret not giving my energy to a healthier lifestyle and am wondering how long it will take for the Wegovy to leave my system. Please take all side effects into consideration before taking."

3 / 10
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  • Mimi
  • Taken for 1 to 6 months
  • July 7, 2023

Ozempic (semaglutide) "Since my first injection, I have felt utterly dreadful. The nausea is one thing, but I have constant fatigue that prevents me from leading my normal life. I know it suppresses appetite, but I don’t have ANY appetite at all and cannot face food. I know if I eat, I will feel a bit better, but it’s impossible. I actually feel like I’ve been drugged. Yes, the ‘food noise’ has gone, and I no longer overeat or binge, but I feel like everything is suppressed - like I’m on a strong drug. I did 4 weeks at 0.25 and have just done one week at 0.5, but I can’t do this anymore. I feel utterly dreadful. I am so pleased it’s helping so many people, but more research is needed into why some people just can’t tolerate it."

3 / 10
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  • Karen
  • Taken for 1 to 6 months
  • June 29, 2023

Ozempic (semaglutide) "Been on Ozempic for 6 weeks and haven't lost any weight. I have been dieting along with Ozempic, but can't seem to lose this weight. I will stick with it another 4 weeks and see what happens."

3 / 10
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  • Archie
  • Taken for less than 1 month
  • May 31, 2023

Ozempic (semaglutide) "I just started on May 1st at 0.25 mg and so far there has been no change in my weight. I'm still in the same range I was before starting (i.e. 245-250lbs). I still feel hungry during certain periods of the day. I try to eat fruit, etc. It may be early, so I am hoping the next dosage or the one after will help with the hunger. I have changed my diet and eat a plant-based diet with a lot of fiber."

3 / 10
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  • Joe
  • Taken for 1 to 6 months
  • May 30, 2023

Wegovy (semaglutide) "Side effects of nausea and vomiting. 0.5mg doses are on serious back order, so went to 1mg dose. No longer taking due to side effects."

3 / 10
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  • ACDWa...
  • Taken for 1 to 6 months
  • May 27, 2023

Ozempic (semaglutide) "I have experienced severe gas, belching, flatulence, moderate nausea all night, not heartburn but feels like seasickness, and moderate constipation. Have had about a 7 pounds weight loss in a month. Simple to use with no problems injecting or at the injection site."

3 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • May 24, 2023

Wegovy (semaglutide) "Easy to administer but during first few weeks had zero weight loss. Dose was increased. Woke in the middle of night after last dose with severe heartburn. Vomited every four hours for two days. Missed day of work. Not able to keep anything down including water. Put on anti nausea medication. Have to sleep in sitting position and take antacids and prescription meds to control heartburn enough to sleep. Cannot wait for medication to get out of system so I can function without vomiting or constant heartburn."

3 / 10
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  • Patsy...
  • Taken for 1 to 6 months
  • May 22, 2023

"No weight loss, the pen leaks most of the medication out so I don't get the full effect of the med. This is the third injection and all three have leaked out."

3 / 10
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  • Justina
  • Taken for less than 1 month
  • May 13, 2023

Ozempic (semaglutide) "I started ozempic .5mg once a week. I have taken it for 3 weeks. I have had to stop it because I have been so sick. I have had massively bad headaches, nausea, vomiting, and stomach pain. After the first injection, I ended up in the ER because of my stomach pain, and then again 5 days later. I haven't been able to keep anything down. I can barely keep 2 sips of water down. I can't even take any of my prescription medications because I am constantly throwing them back up. My doctor told me to stop taking it. My husband says I've lost weight but that's only because I'm constantly throwing everything up."

3 / 10
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  • Lynne
  • Taken for less than 1 month
  • May 10, 2023

Wegovy (semaglutide) "I haven't noticed much weight loss with this medication. I have experienced extreme nausea to almost vomiting. I have also suffered from daily headaches from this medication. I have also noticed my blood pressure fluctuates higher than my normal high. I am only on the 1.0 mg dosage right now and my doctor will increase it next week. I do have to say the pens are very easy to use and the needle injections don't hurt."

3 / 10
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  • Anonymous
  • Taken for less than 1 month
  • May 1, 2023

"A horrendous coughing fit led to a pulled neck and intense pain. 10 days of reflux meds, painkillers, antibiotics, and steroids to resolve it but had to miss work. It was an effective appetite suppressant. Unfortunately, when I requested a half-injection, I was told it would not work."

3 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.