Semaglutide for Weight Loss (Obesity/Overweight) User Reviews (Page 2)
Brand names: Ozempic, Wegovy, Rybelsus
Semaglutide has an average rating of 7.3 out of 10 from a total of 613 reviews for the treatment of Weight Loss (Obesity/Overweight). 63% of reviewers reported a positive experience, while 19% reported a negative experience.
Reviews for Semaglutide
- Danie...
- Taken for 1 to 6 months
- April 5, 2023
Wegovy (semaglutide) "I wanted to warn people of the side effects as my doctor did not prepare me for this med. I am very glad I didn't try to work otherwise I would have lost my job or at the very least been written up for various reasons. On it for a month. I tried spacing out the second shot and never ended up taking the last injection. Side effects: Severe fatigue, severe hair loss, decreased hormones, severe headaches, changes in your sleep architecture, bad nightmares for all sleep, naps, and overnight. Warning if you have PTSD that may mess with you. Bladder urgency and uti symptoms started on day 3 and were constant the whole time on the med, had to take AZO. Bloating, burping, throwing up, and all food smells make you sick, severe constipation, hypoglycemia, and increased binge eating. I also had increased topical psoriasis and arthritis pain. Started having problems with my foot and wondering if impacting ligaments. I am getting that checked out. Did not reduce the need to eat, no weight loss."
- laura
- Taken for less than 1 month
- April 3, 2023
"Took one 0.5 shot. Will not be taking any more. Constant nausea, diarrhea, dry heaving, and rotten egg burps. It has been nine days now since the shot and only just starting to feel human but the symptoms are still there. I honestly have felt like I have some terrible sickness bug. The sulfur burps my whole family can smell ...like 5 minutes later if they walk in the room. No idea what poison this is, but for someone who has rarely had side effects of medication..this is awful."
Frequently asked questions
- Tirzepatide vs semaglutide: How do they compare?
- How does semaglutide work for weight loss?
- Why am I not losing weight on Ozempic?
- How much does semaglutide cost?
- Waste...
- Taken for 1 to 6 months
- March 31, 2023
Ozempic (semaglutide) "Honestly a complete waste of money, it did absolutely nothing"
- Mamac...
- March 27, 2023
"By far the worst medication I have ever taken in my life. It made me so sick, I had diarrhea and was constantly burping. It was terrible. I may never eat a boiled egg again. Of course, you can lose weight on it, but you’re too sick to function."
Are you taking this medicine?
- Anna
- Taken for less than 1 month
- March 25, 2023
Ozempic (semaglutide) "I have been taking Ozempic for three weeks and the first week wasn't so bad with the stomach cramps (off and on). Second week the cramps were the same, but diarrhea got worse. By the third week, the cramps are worse and the diarrhea is seriously worse after every meal (watery). Obviously, I will discontinue use at this point. However, I do have an underlying condition: IBS-D. Just for your information. Good luck to all."
- Tressa
- Taken for less than 1 month
- March 25, 2023
Wegovy (semaglutide) "I have been on this medication for one week. On the second day I was very tired, on days 3-6 I was nauseous the whole time. Every time I ate something other than toast or crackers, I had major cramping. Plus a mild headache all week. This was a horrible experience. The pain felt like a gallbladder attack. Never again."
More FAQ
- How does Ozempic affect blood pressure?
- How does taking Ozempic affect your face?
- What foods should I eat or avoid when taking Rybelsus?
- Why does Ozempic cause a dry mouth or taste changes?
- TooTr...
- March 21, 2023
Ozempic (semaglutide) "My first dose made me sick as a dog 2 days after the injection. Nausea, felt like I could vomit, and kept swallowing over and over again. Cold chills, it was awful! I do not plan to continue. No pain, no gain. I’ll get my loss the old-fashioned way with proper diet and exercise. Never again want to feel this way on Ozempic."
- Diabeat
- Taken for less than 1 month
- March 16, 2023
Wegovy (semaglutide) "Well I'd know how great it was if I could actually get it injected. I am a insulin dependent diabetic and have taken other glps as well as insulin, with all types of injectors so pharma can charge exorbitant prices. The Wegovy injector is one time use. If you don't do it right, you don't get that dose. If you don't push hard enough (keep in mind you inject it into soft fatty areas on a soft fat body) and maintain the pressure perfectly, you end up wet and not getting your dose, because once it starts dispensing. Having a "proprietary" injector, as well as single use, allows Novo Nordisk to charge $640 for a single injection (Ozempic is multiuse injector at far less price, same med). So yeah, twice now I have not gotten my dose, and it is sickening to throw $1200 away. The drug is not worth the loss when you have other choices. Calling Novo Nordisk did nothing, no coupon, no replacement."
- Jackie
- Taken for less than 1 month
- March 12, 2023
Wegovy (semaglutide) "Worst medication ever. On the lowest dose, I became deathly ill. I couldn't stop vomiting for a week. I could not walk because of extreme dizziness, and I could barely see from blurry vision. It also gave me the worst migraine of my life and suicidal thoughts and depression. I only lost weight because I could not eat at all and couldn't keep liquids down, so I was severely dehydrated. The side effects and long-term effects are so severe that the minor weight loss you would have from this medication is not worth it."
- lara
- Taken for less than 1 month
- March 10, 2023
Ozempic (semaglutide) "I became so dehydrated I couldn't get up. I had severe muscle spasms, severe nausea, and vomiting. I did lose weight but the side effects were not worth it. I was in bed for over a week."
- Ride
- Taken for less than 1 month
- March 9, 2023
"I’ve only taken 2 doses and I have broken out in a tiny blister rash from my waist to my ankles. Very itchy and bothersome. It’s been 4 days and the rash gets worse with each passing day. I guess I am one of those people that can’t take it"
- Tina...
- Taken for 1 to 6 months
- March 3, 2023
Ozempic (semaglutide) "It caused a severe case of acid reflux and gastric distress along with chest pain and swollen glands. I could not eat for a week because my digestive system was so negatively affected."
- Anonymous
- Taken for less than 1 month
- February 24, 2023
Ozempic (semaglutide) "Horrible experience. I only took 2 dosages because I had difficulty functioning with headaches, eye pain, nausea, dizziness, and overall feeling awful. The additional issue is I've been off the drug for a week and can't get rid of the symptoms. I'm nauseous every day, with headaches, and dizziness. How long until all of this goes away?"
- January
- Taken for less than 1 month
- January 9, 2023
Wegovy (semaglutide) "Took my first 0.25mg Wegovy dose yesterday. I felt nauseous about an hour later but within 2 hours I started vomiting. For the next 16 hours, I dry heaved throughout the day and night. I couldn't even keep water down. It hasn’t been a full 24 hours yet since I took the shot and feel horrible, hoping that these side effects will stop soon. There is no way I’m taking another shot next week."
- MM...
- Taken for 1 to 6 months
- December 22, 2022
Wegovy (semaglutide) "Wegovy has agonizing side effects. I had to quit after 2 months. Constant uncontrollable vomiting, I vomited at work, and while driving (which was horrific and dangerous). I essentially became bulimic, and afraid to eat. I lost 20 pounds but put half of it back right away. Not worth the agony."
- Annal...
- Taken for 1 to 6 months
- December 13, 2022
"I tried semaglutide for three months (with two different health providers) and did not lose a single ounce. None was able to explain why it was not working."
- Penn
- Taken for less than 1 month
- October 31, 2022
Wegovy (semaglutide) "Don't use it !!! After having this I was in bed 6 days and had to go to hospital to get hydration due to risk of my kidneys I felt as though this was a poision going through my body and almost immediately nauseous and could not keep anything down Don't do it"
- No...
- Taken for 1 to 6 months
- September 18, 2022
Wegovy (semaglutide) "I took it for 6 months. Wanted to get to 2.4 because I kept thinking it would start working. No measurable weight loss or benefits. Lost 5 pounds. However, I have massive hair loss. Other minor symptoms like nausea. Would not recommend."
- Har
- September 16, 2022
Wegovy (semaglutide) "Avoid this injection. I took my first dose few weeks ago and I have never been so sick. Constant vomiting after 4 hours, throwing up bile. Ended up in hospital has I became dehydrated. Week later still got on and off vomiting. The reflux is terrible and can't eat anything. It's better to be yourself than go through all this"
- LRK
- August 24, 2022
"This is the third month of being on Semaglutide and the second time I have had SEVERE gut issues...pain so bad I cannot stand up straight, and this has been going on for three days now. Second time this has happened. I cannot stand how this medication makes you feel, either. It is horrible. And yes, it makes you lose weight coz you cannot eat, so you are literally starving yourself so of course the weight comes off. The one thing that is NOT TALKED ABOUT is the fact that when you go off this medication you WILL PUT THE WEIGHT BACK ON. PERIOD. So, this is not affordable for most, makes you feel absolutely horrible...nausea, stomach pain, blurred vision, irregular heartbeat, nightmares, and the list goes on. My husband tried this as well and had to stop coz it caused hypoglycemia with him, he could not remember what he was doing, think straight, brain fog. He had to stop taking it, and I am about to stop taking this as well. I am sick of feeling sick on this medication!"
- Gma
- Taken for less than 1 month
- August 17, 2022
Wegovy (semaglutide) "I was given the max dose 1st which was huge mistake it’s been 7 days of vomiting, weakness, headaches still can’t eat anything this medication is very scary."
- KCI
- Taken for 1 to 6 months
- August 11, 2022
Wegovy (semaglutide) "The auto injector is AWFUL. It would seem easy, push firmly down, wait for the clicks, count to 10. When I’ve tried pushing into my abdomen and keeping a firm surface, I damn near feel like I’ve pushed 3 inches into my abdomen and device never engages. When it does, the medication spills down my stomach. When I switched to my thigh, again, you have to push so damn hard to get it to work. It is awful. I asked my doc to take me off Wegovy and try another product."
- Becku
- Taken for less than 1 month
- August 10, 2022
"Taking for weight loss. After first injection (.5) had horrible migraine. Which I’m prone to but I also had severe nausea and acid reflux. Took my second dose yesterday (1) and ended up throwing up anything I tried to eat, been extremely nauseous today. My goal is 40 Lbs but I’m not sure I’m going to continue, I can’t function with all the nausea. I’ve lost 3 Lbs but I’m not sure it’s worth it."
- Anonymous
- Taken for less than 1 month
- July 29, 2022
"I took 2 injections. First injection, nausea by day 2-4, diarrhea day 3-5. It does curb appetite. I also had my anxiety increase (not sure if because my system was upset, but it increased). Second injection - severe nausea day 1-3, vomiting day 1-2, diarrhea day 3-5, crying / anxious day 3-5. Once again curbed appetite. I will be discontinuing drug. Not for me at all. I tried it and that’s all. But, I do have Hashimoto’s and my body is always sensitive to new meds."
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.
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Care guides
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"The absolute worst medication I have ever been prescribed. It made me vomit uncontrollably after the second injection and I ended up in the emergency room. 10 days later I still feel awful. I cannot eat more than two or three bites of food at a time without getting sick."