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Semaglutide for Diabetes, Type 2 User Reviews (Page 4)

Brand names: Ozempic, Wegovy, Rybelsus

Semaglutide has an average rating of 6.4 out of 10 from a total of 1114 reviews for the treatment of Diabetes, Type 2. 49% of reviewers reported a positive experience, while 26% reported a negative experience.

Reviews for Semaglutide

  • Jobob
  • Taken for 1 to 6 months
  • November 2, 2020

Ozempic (semaglutide) "I have taken Ozempic for a month now, dosage being 0.25 once a week. At first, I didn’t really see any side effects or anything, but then one day I made the mistake and overate, resulting in constant gas, repeated burping, and an hour later, non-stop diarrhea. After that experience, I have learned never to do that again. I now usually eat a big breakfast and a snack later on throughout the day, which has helped me completely cut out soda. I originally started taking this because I was experiencing rapid weight gain. They checked my thyroid and said it was within normal limits, so they put me on Ozempic, and I am so glad. In the morning, I haven’t had a blood sugar reading over 130 in a month. I am looking forward to going back to my doctor to figure out my A1C. In total, I’ve lost 8 pounds in one month :)"

10 / 10
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  • Laurel
  • Taken for 1 to 6 months
  • April 1, 2020

Ozempic (semaglutide) "I have been prescribed Ozempic for weight loss secondary to type 2. I got nauseated with some loss of appetite at 0.25 mg dosage and adapted to it over a month. Lost 9 lbs in that month. I increased to 0.5 mg last Friday (it is Tuesday), and I am miserable. Non-stop nausea, burping, some pain in the stomach, constipated. I feel miserable. I am worried about the stomach pain being pancreatitis starting, so I am increasing my water. I haven't eaten in two days. I will not continue with this drug as I think this just cannot be a good thing to do to one's body."

3 / 10
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  • Miser...
  • Taken for 1 to 6 months
  • May 27, 2020

Ozempic (semaglutide) "Started Ozempic 8 weeks ago, from the beginning I started belching. Dose was 0.25, went to 0.50 and the stomach cramps started. I am in 3 weeks now at 1mg and I have never been more miserable. Constant violent diarrhea and stomach cramps. I am losing weight at a rapid pace, didn’t necessarily need to lose. I called the doctor today because I’m unable to leave the house; she seems to think that this will subside in another week and I should be back to normal. After reading everyone’s comments I find this hard to believe!"

2 / 10
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Frequently asked questions

  • Oly
  • Taken for 6 months to 1 year
  • July 6, 2021

Ozempic (semaglutide) "Been taking for 18 months. I have lost 50 pounds. My last two labs (3 months apart), A1C 5.2 and 5.3. Along with Ozempic, I take Jardiance and Metformin. I have no craving for my former favorite foods. Honestly, I get no pleasure from eating. It works for me, my miracle drug."

10 / 10
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  • Pat
  • July 19, 2019

Ozempic (semaglutide) "Started taking Ozempic for pre-diabetes and insulin resistance. This is the first medication I've ever taken for diabetes. A1c was 5.7. I increased the dose quickly at the doctor's recommendation if little to no side effects occurred. First dose 0.25 in the office. Second 0.5 a week later. Third dose at 1.0 a week after that. Only side effect I have is mild nausea. Appetite has disappeared, and I eat only when hungry and much smaller portions. Serious bloating when I eat too much, which is a great deterrent. Been on the medication for 4 weeks overall, 2 weeks at 1.0, weight dropped from 305 lbs. to 295 lbs. Still a little lethargic, but I was very lethargic before starting the medication. I feel like this medicine is a game changer for me. I love not thinking about food all of the time, only eating when hungry and not for pleasure, and losing weight. Will retest A1c in 2 months. Hopefully, the weight loss continues, and I caught the A1c level before it turns into full-blown diabetes."

10 / 10
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Are you taking this medicine?

  • Sue
  • Taken for 6 months to 1 year
  • July 25, 2021

Rybelsus (semaglutide) "I started this 7mg along with 1000mg of Metformin in August of 2020 and I have lost over 65 pounds. I was insulin resistant and could not lose weight regardless of my diet. I’m 56 years old and this has been the easiest weight loss I have ever had and I have done it all. I did begin with a low carb diet but now I eat what I want in moderation. It had definitely helped with my appetite and I feel full quickly. I am under a doctors supervision and go monthly and all of my numbers are great. It may not work for everyone but for me it’s been a lifesaver."

10 / 10
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  • Bunk
  • Taken for 1 to 6 months
  • October 11, 2020

Rybelsus (semaglutide) "I have read a lot of the comments. This medication has helped lower my A1C. I am down from an 8.1 to a 6.5. When I started it, I was weighing 238 pounds, now I weigh 217. I was wearing a size 18W/20W, now I am at size 16W. I don't want to get too small. I like the way my clothes fit on me. The only thing that I have read about taking this medicine is that it can cause Thyroid cancer. So I may stop taking it."

10 / 10
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More FAQ

  • Anonymous
  • September 26, 2020

Ozempic (semaglutide) "It's the miracle drug. It reduced my A1C from 11.3 to 5.4 so far. I've been taking it for a little over one year, lost some weight, and no side effects whatsoever since the first dosage. I quit taking metformin and do watch my sugar intake, not religiously, but moderately. It does work! Price with insurance is only $25 compared to $800 without insurance. Highly recommended."

10 / 10
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  • John
  • Taken for 1 to 6 months
  • February 7, 2020

Ozempic (semaglutide) "I have lost more than 30 lbs. In the 3 months I've been on it. For the first month, I had a mild sour stomach, but it wasn't that bad. I feel fine now and am still losing weight. My blood tests are within normal ranges. I feel fine. I'm in my 50s and haven't been this weight since my teens."

10 / 10
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  • Cas
  • Taken for 1 to 6 months
  • January 18, 2021

Ozempic (semaglutide) "Ozempic has been a life changing medicine for me. My A1C is better controlled and I have have lost around 13 pounds so far and have not even been on it that long. Before ozempic, I craved sweets and was constantly hungry ozempic has greatly helped me regulate my appetite. If I eat too much I do have problems with nausea, so I do have to be careful, but that’s a good side effect I think"

10 / 10
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  • Onward
  • Taken for 1 to 6 months
  • July 18, 2021

Ozempic (semaglutide) "I am male (early 50s). Blood glucose was already regulated with metformin, diet, and exercise (100 to 150), but I wanted to quit metformin because of its side effects (diarrhea). I was put on 0.50 mg/wk and warned that nausea from Ozempic was a common side effect. I HAD NO IDEA! WEEK 1/WEEK 2: I couldn't smell food without getting queasy. I choked down lots of soup just to get 1200 cal/day (often falling short). WEEK 3/WEEK 4 got slightly better. WEEK 5: I have my appetite back. I feel full, so I eat smaller meals. My weight loss is atypical: 203 lbs to 183 lbs in five weeks, combined with exercise (1 hr/4x wk stationary bike/treadmill). Blood glucose is now between 90 and 120, with occasional dips and peaks. I would only recommend this drug to those who have very high glucose levels, are morbidly obese, fiercely stubborn, and/or desperate. But it works. Good luck."

8 / 10
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  • Val
  • Taken for less than 1 month
  • February 14, 2020

Ozempic (semaglutide) "I’m a nurse. I started this med and unfortunately the nausea, gastritis, dizziness, and headache continuing into week 4 is simply not worth it. I can’t lay in bed and be miserable, which is what this does to me. At first, I actually thought I had a GI Bug. If there is any other choice, do not put yourself through this."

5 / 10
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  • Missy
  • Taken for 6 months to 1 year
  • August 14, 2020

Rybelsus (semaglutide) "Started Rybelsus when it first came out in October 2019. Took 3 mg at first and my glucose levels started to rise. Changed to 14 mg and was on that for 6 months. Glucose went very low - I was tired and weak. A1C went from 10.1 to 5.2. Changed to 7 mg and feel so much better, glucose levels are still within normal limits. I've had no side effects and great results. I do take this with 5 mg of Glipizide - once a day. Have tried many diabetic drugs and Rybelsus has worked the best. I've had a slight weight loss... under 10 lbs. So glad I tried this drug. It's a winner in my book."

10 / 10
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  • lulubug
  • Taken for 1 to 6 months
  • February 25, 2020

Ozempic (semaglutide) "Well, let me start by saying Ozempic worked very well for me. I was on it for a little over 4 months. I lost 49 pounds, my A1C went from over 9 to 6.7, I'm off insulin now. Then we went to a higher deductible insurance plan and I can no longer afford my Ozempic. The only thing they offer is the $150 savings card, so it still costs over $600 a month. I can have a roof over my head or get my meds. What a world we live in. I guess I should quit my job, then I could get some assistance with it."

10 / 10
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  • Senzuel
  • August 29, 2019

Ozempic (semaglutide) "I've been taking Ozempic for about 2 months to lower my Diabetes 2. It's been great; my numbers were 200 to 300, they are now 100-134. My A1c was 9.8, it is now 6.1, and I've lost 12 lbs and still losing. I'm also taking Synjardy XR, a combination of (Metformin & Jardiance); my numbers are great. I eat extremely less on the Ozempic. My only side effect has been an occasional headache, but nausea was brutal. I was getting very nauseated after eating and taking Synjardy XR until I heard about ZOFRAN. Let me just say, if you have nausea and are taking Metformin with Ozempic, PLEASE ask your doctor for a prescription of ZOFRAN (I got the generic ONDANSETRON 4mg). I take it 20 minutes after I eat and have taken my metformin. I NO LONGER get nausea. Zofran will definitely help with nausea if you're feeling sick. You'll thank me later."

10 / 10
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  • Losin...
  • November 10, 2019

Ozempic (semaglutide) "I am a 70-year-old type 2 diabetic and was taking one Metformin 500 ER for the past year or so. My A1C was 11, and it dropped to 5.6 by changing my diet and taking the Metformin. My doctor wanted me to try Ozempic to help me lose weight and possibly eliminate the Metformin. The side effects were terrible right from the start. Nausea and diarrhea, no vomiting, just nausea. I started at 0.25 and am now up to 1.0. My appetite is gone completely. I have no desire to eat at all. When I do eat, I get full almost immediately. I have gone from 228 lb down to 202 lb in the six weeks I have been taking Ozempic. I'm thrilled with the weight loss, and the nausea and diarrhea have improved. However, I have almost stopped peeing. I go in the morning, then go all day into the evening without going. Since I suffer from incontinence, it's good, but I am worried that it might be damaging my kidneys. I hope I don't have to stop taking it, at least till I lose another 50 pounds or so."

7 / 10
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  • Hazel
  • Taken for 1 to 6 months
  • September 18, 2019

Ozempic (semaglutide) "Blood sugar levels started getting high 33 a year ago, tried several different prescriptions before being placed on Ozempic (4 months ago), metformin & Invokana. Now reading 6.5 levels, with a recent 7.0 A1C. In the past 4 months have gone from 170 to 141 lbs. I was told weight loss included muscle loss so I’m trying to keep on a high-protein diet and weight workouts. I don’t think I’ve had a hunger pang in 4 months, and eat way less. I do get burps after eating and occasional stomach pain that is tolerable. Perhaps it’s the combination of all bringing down my levels that gives me two things I didn’t expect, clear clarity in thinking (better memory recall) and a lot more energy (as in stable for a good 10 hours and then I start getting fatigued). I honestly am very happy to lose weight and eat off a smaller plate."

10 / 10
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  • Janice
  • Taken for 6 months to 1 year
  • May 26, 2021

Ozempic (semaglutide) "I started Ozempic in July 2020. The first few weeks I had slight nausea. Now, 10 months in I’ve lost 50lbs - 210lb to 158lb and my sugar levels if anything are on the low side. I’ve just stopped taking my Metformin as they were dropping too much. I didn’t even make it to the 1mg, stopping at the .5mg. If you can last the first 4 weeks, it’s amazing. The only side effect I have is a little constipation which I control with PEG when needed. It has changed my life! I feel like a brand new woman!"

10 / 10
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  • Isabel
  • Taken for 1 to 6 months
  • September 24, 2020

Rybelsus (semaglutide) "My endocrinologist prescribed 3 mg to start because the B12 depletion from metformin (I have b12 anemia) was not good and constant yeast infections from Forxiga were very annoying. At first, I noticed a major appetite decline. There was a bit of nausea for the first 2 weeks. I started the 7 mg after a month and while I've been experiencing constipation, I am so happy about the weight loss. I've been on Rybesus for 10 weeks and have lost 10 lbs. My latest random glucose test had me at 5.7, down from 6.3 - 7 over the previous few months. I am happy about fewer carb cravings and will stay on Rybelsus as long as I can. I am lucky my health plan covers it because it's quite expensive."

10 / 10
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  • Psyop
  • Taken for less than 1 month
  • September 28, 2020

Rybelsus (semaglutide) "Started on Rybelsus 20 days ago after I went in to see my doctor and my A1C was 11, this is while I was also taking pioglidazone and 2000mg metformin. After being on it for only 20 days it has brought my blood sugar average down from 269 to 131. My 14 day glucose is 114, and my 7 day average is down to 109. I am hopeful that my next A1C reading will be 5.6. I did notice a little looser stool when I started it, but nothing worse then when I started Metformin. So far, So good. My only complaint is how expensive it is! I may not be able to continue it because of the cost."

10 / 10
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  • Iamal...
  • Taken for less than 1 month
  • January 24, 2021

Ozempic (semaglutide) "Today is day 10 on .25 mg of Ozempic, so 2 doses in. On day 7 (dose 2 injection day) I could not leave the toilet. Exhausted and cold. Never any desire to eat, even if I haven’t eaten for 24 hours. When I do eat something it is a tiny portion and I feel incredibly sick for an hour or so afterwards. Last night I had horrifying nightmares. I cannot wait for this to wear off, I will change my lifestyle long before I take another dose of this medication."

1 / 10
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  • Karan
  • Taken for 1 to 6 months
  • March 10, 2020

Ozempic (semaglutide) "This is my 8th week and using 0.5. I lost 12 lb and I have more energy now so I go to exercise as well now. Only on the first week I have heavy headache but it was gone on my second week. I thought of stopping it after the first week due to the headache but luckily I continued and I am having a happy life now."

10 / 10
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  • Dimples
  • April 7, 2020

Ozempic (semaglutide) "Been using Ozempic for 7 weeks, lost 12 pounds. I also take Xigduo and Lantus at night. Gas, nausea, headache, and a few low A1c. But my number is down from 8.1 to 5.4. For the gas, I find that Gas-X helps. And for the nausea, I sip on cold water and keep my meals small. I haven't thrown up yet and no constipation or diarrhea."

5 / 10
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  • Daddy...
  • Taken for 6 months to 1 year
  • October 13, 2019

Ozempic (semaglutide) "This Ozempic was prescribed as a last-ditch effort to get my A1C down prior to starting insulin. The first 0.25 dose caused significant nausea, but I battled through it for a couple of weeks before starting the 0.50 dose. The nausea increased with the higher dose, and I considered stopping but had lost ten pounds, had zero appetite, and my sugar was down, so I chose to continue. It's been about 6 months now; I'm taking the full 1.0 dose, and although the nausea is still an issue, it has lessened in severity and comes in 'waves,' so I know it will pass and just tough it through. I've dropped about 30 lbs and counting; my A1C is now in the prediabetic range, and I've been able to lower doses of other medications that were causing significant side effects. I now feel better, look better, have more energy, and no longer have the constant food cravings or desire to overeat. If you can ride out the nausea, the benefits of Ozempic are huge, for me anyway."

8 / 10
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  • Ashsc...
  • May 12, 2021

Rybelsus (semaglutide) "My endocrinologist prescribed this to help with PCOS. I weighed 211lb and started on 3mg and lost 6 lbs while walking for 2 miles a day most days for a month. I was bumped up to 7mg, but insurance wouldn't cover it and I ended up gaining the weight back after trying Victoza and Byetta. My insurance changed and my endocrinologist started me back on it at 7mg since I already had Byetta in my system. During this time, I found out I have Ehlers-Danlos and was recommended to start weight lifting to help strengthen my muscles and lost 13 lbs in a little over a month which I'm sure exercise has helped contribute. My menstrual cycle has been regular and on time for the first time in 4 years. I haven't had any major side effects other than a little nausea when I first take it in the morning and diarrhea, but I had that issue beforehand. I know a lot of people have said the side effects are terrible, but it hasn't been for me and you should certainly give it a try. It's honestly been wonderful."

10 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.