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Crestor and Weight Gain: What Users Say

Weight gain: mentioned by 7 users (5.1%)

Based on user experiences from 138 Crestor reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

pain 20.3%
muscle pain 19.6%
joint pain 15.2%
weakness 11.6%
cramps 10.9%
dizziness 6.5%
insomnia 6.5%
muscle aches 5.1%
weight gain 5.1%
fatigue 4.3%

Reviews for Crestor

Commonly mentioned side effects
  • Jac...
  • Taken for 1 to 2 years
  • November 1, 2020

For High Cholesterol "Been on Crestor for about a year. Cholesterol about 260 and I’m 55 years old, but all my life I’ve been fit and lean, and my cholesterol has always been around 220 since I’m 18 years old! My good cholesterol (HDL) is on the high side, but of course, the bad one (LDL) seems to be creeping up! My issue is my elbows started hurting with pain pricks and sharp knife-like pain, so I went to the doctor. She told me to stop taking the medicine for a couple of weeks to see if the pain would go away. The pain didn’t go away, so I went back on it, only 5mg. I’m feeling fatigued, muscles seem to feel weak, and I’m not sure if it’s from the medicine or just my age. I also gained a little bit of weight. If anyone has any comments, please let me know. Thank you! Also, my triglycerides used to be very low, and since taking this medicine, they went up at least by 50."

4 / 10
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  • Gra...
  • April 6, 2016

For High Cholesterol "Within 3 days of taking Crestor 10 mg, I got terrible leg cramps, headaches, nausea, and weakness. On top of that, I had awful dreams that were scary. Within one week, I gained 8 pounds. I felt sick. Got off of it and just did exercise and watched my diet closely. Lost 16 pounds in a month, and 3 months later, my cholesterol went down from 350 to 169. I feel so much better, and all the bad symptoms went away. Crestor is not for everyone."

1 / 10
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151 Report
  • Luc...
  • Taken for 6 months to 1 year
  • April 23, 2020

For Prevention of Cardiovascular Disease "I was prescribed Crestor after a triple bypass. 40mg daily and I finally weaned myself off of this drug after 7 1/2 months due to side effects. I was to the point where I could barely walk, my knees and feet were extremely painful. My shoulder joints had me in rehab therapy also. No energy, weight gain, and a thumb that now locks in place which is anything but pleasant. All these symptoms have significantly eased up and hoping to get back to 95% of my old self!"

2 / 10
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90 Report

Frequently asked questions

  • Anonymous
  • January 11, 2012

For High Cholesterol "Crestor lowered my cholesterol and triglycerides, but I noticed weight gain (20 pounds in a year) and tiredness and no energy. I started having chest pains, arm pain, jaw pain. Cardiologist did a catheterization and found nothing to warrant the symptoms I was having. I stopped the Crestor and within 2 to 3 weeks I feel back to normal and dropped 8 pounds! I have increased my fish oil intake and paying more attention to diet hopefully won't have to go back on another statin."

2 / 10
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175 Report
  • mid...
  • Taken for 6 months to 1 year
  • May 9, 2013

For High Cholesterol, Familial Heterozygous "5 mg Crestor for about 3 weeks after becoming menopausal and having cholesterol spike even higher (family genetic condition) - no side effects at first and numbers started to improve. THEN - everything went haywire - rapid weight gain & all symptoms of pre-menopause have come back. Now having severe joint pain so have stopped taking it completely."

3 / 10
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83 Report

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  • LAd...
  • November 12, 2015

For High Cholesterol "Gained 8 pounds in two months, wearing a splint for my left wrist due to extreme tendon/muscle pain, can't lift anything. Also noticed that I can't lift any of the weights that I used to be able to at the gym as my upper body isn't as strong as it used to be. Had blood work yesterday, so I don't know if it lowered my cholesterol (300 range), but Dr. is taking me off (5mg) it for a month."

3 / 10
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  • cjg...
  • Taken for less than 1 month
  • November 18, 2020

For High Cholesterol "2nd time on Crestor. Stopped taking the first time due to leg pain. Tried it again and had side effects of gained weight, my GERD increased, had trouble getting my legs to move, nightmares, intermittent blurred vision, increased left hip pain, so I had to curl my leg up in bed instead of leaving it straight, which caused pain. I had a hard time driving due to blurry vision. Crestor is an expensive medicine. Because the HDL cholesterol numbers are decreased, well, I don't know if we know enough about cholesterol to know how much it helps. Could not stay on it long enough to see if it helped the HDL."

1 / 10
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29 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.