Crestor and Weakness: What Users Say

• Moa...
• Taken for 1 to 6 months
• September 22, 2019

For High Cholesterol "After being on Crestor, it initially brought down my levels significantly within a month. However, after 3 months, I began to feel somewhat depressed, have joint aches, feel unmotivated, experience fatigue, and overall muscle weakness. Grabbing a case of water at the market was beginning to make me feel like an old lady. I stopped taking the medication and within a week I started to feel better. I could tell that my overall health was compromised. I would not take this again."

• MeR...
• Taken for less than 1 month
• February 26, 2020

For High Cholesterol "Started taking 10 mg yesterday. After about 2 hours, I had severe leg cramps. Yesterday, I thought it was maybe flu or something. Then, today again after a couple of hours of taking it, the cramps and weakness started. There is no way I am taking this again. I would rather die of a heart attack than be in a wheelchair."

• Jac...
• Taken for 1 to 2 years
• November 1, 2020

For High Cholesterol "Been on Crestor for about a year. Cholesterol about 260 and I’m 55 years old, but all my life I’ve been fit and lean, and my cholesterol has always been around 220 since I’m 18 years old! My good cholesterol (HDL) is on the high side, but of course, the bad one (LDL) seems to be creeping up! My issue is my elbows started hurting with pain pricks and sharp knife-like pain, so I went to the doctor. She told me to stop taking the medicine for a couple of weeks to see if the pain would go away. The pain didn’t go away, so I went back on it, only 5mg. I’m feeling fatigued, muscles seem to feel weak, and I’m not sure if it’s from the medicine or just my age. I also gained a little bit of weight. If anyone has any comments, please let me know. Thank you! Also, my triglycerides used to be very low, and since taking this medicine, they went up at least by 50."

• Bil...
• March 6, 2019

For High Cholesterol "Could not get up from a chair after taking Crestor generic. Then I stopped taking the drug two weeks ago and still have trouble with muscle weakness and pain. It is very painful to enter a car and to sleep at night. I failed to mention the problems with my joints in my fingers and toes stiffness and cramps."

• Gra...
• April 6, 2016

For High Cholesterol "Within 3 days of taking Crestor 10 mg, I got terrible leg cramps, headaches, nausea, and weakness. On top of that, I had awful dreams that were scary. Within one week, I gained 8 pounds. I felt sick. Got off of it and just did exercise and watched my diet closely. Lost 16 pounds in a month, and 3 months later, my cholesterol went down from 350 to 169. I feel so much better, and all the bad symptoms went away. Crestor is not for everyone."

• Anonymous
• July 16, 2016

For High Cholesterol "I took Crestor for about two years with minor side effects. Since I turned 65, I noticed my leg muscles (hamstrings, knees) were hurting. I stopped taking Crestor, and my legs feel better. The drug did help lower my cholesterol, but my legs were killing me, and I had trouble walking due to the stiffness and pain. While I am not 100% certain my leg pain was due to Crestor, it certainly looks that way. It has only been 6 days since I stopped."

• geo...
• December 7, 2010

For High Cholesterol "I have taken 10mg of Crestor for 3 yrs. I have experienced several issues with this statin as well as others. After 8 weeks on Crestor my HDL went from 289 to 79, on paper, I looked great! But over the last several years of taking statins, I have experienced several bad side effects. Severe bone and muscle pain, loss of muscle mass. I felt depressed, lots of mood changes. I became a wimp in bed. After taking statins for 5 yrs, I went to a cardiologist and had several things checked, nothing wrong. But recently, had blood test that showed problems with muscle and bone loss. STOPPED. After a couple of weeks I am feeling great. Your brain uses cholesterol for basic functioning and to make testosterone."

• cha...
• August 9, 2017

For Prevention of Cardiovascular Disease "Took Crestor for four months and it lowered my cholesterol. Took it until my feet, shins, and calves went into cramps. Couldn't sleep, and could hardly walk. Cramps ended two days after quitting. Cardiologist put me on it and my family doc took me off it and told me never to take it again."

• Bed...
• February 1, 2016

For High Cholesterol "I began on Crestor in 2013. I could not tolerate simvastatin or pravastatin but was told that Crestor was different. After a week on this med I developed severe pain in my legs. I stopped it but the pain did not go away. Three years later I am still in pain, cannot climb stairs or get out of a chair. My muscles in my thighs and rear are wasting away. Five neurologists have failed to help me."

• Apr...
• August 25, 2015

For High Cholesterol "Been on Crestor for almost a month. 20 mg daily for genetic high cholesterol. Triglycerides started at 1100! I immediately noticed the muscle weakness and belly pains. My hips, knees, and ankles ache constantly!"

• Jo ...
• May 11, 2022

For High Cholesterol "For decades, my cholesterol numbers have been high, but because the “good” cholesterol was always much higher, I was never put on any drugs. I always had creative and stressful work, requiring long hours. I also developed HBP, although I don’t drink coffee, only have a recreational drink from time to time, and have never smoked. During an unrelated illness, my BP was high, and so I was started on metoprolol. It did not work well with me at all, so my primary changed it to the lowest dose of carvedilol. My cardiologist increased it. Then he put me on a combination of Zetia (10 mg) and Crestor (5 mg). I can tell you that the combination of all three has put me in hell: joint pain, muscular pain, fogginess, forgetfulness, lethargy, and UTIs. As I write this, I am in bed, not because of a sudden and extreme pain in my right leg last night, muscle weakness, and the most severe cramps ever. The doc will not take me off the meds as they brought the numbers down. But I will."

• jks...
• July 3, 2010

For High Cholesterol "Less than 7 days after beginning Crestor, I had debilitating muscle pain and weakness in my legs. 5 weeks following and treatment by a neurologist who prescribed Lyrica, I am beginning to regain strength in my legs, but I continue to have pain, especially on the right side."

• Anonymous
• October 7, 2018

For High Cholesterol "Destroyed my muscles. Started in legs and spread. Stopped taking two years ago and muscle pain and weakness has not improved. Some recent studies suggest may be permanent. Statins are poison."

• agg...
• June 17, 2014

For High Cholesterol "Side pains, weak legs, muscle stiffness, and poking pains in stomach."

• Mis...
• March 11, 2010

For High Cholesterol "Caused severe muscle pain and weakness. I was sleeping 10 hours."

• jds...
• April 3, 2011

For High Cholesterol "I have never had any problems with any medications until after I had open heart surgery. Crestor is now giving me leg pain and weakness, along with the pale stools."