Skip to main content

Seroquel User Reviews & Ratings

Seroquel has an average rating of 6.8 out of 10 from a total of 494 reviews on Drugs.com. 60% of reviewers reported a positive experience, while 21% reported a negative experience.

Reviews for Seroquel

  • Lawn...
  • Taken for 1 to 6 months
  • March 26, 2023

"I have been on it for two months and it has done absolutely nothing to help me with my anger."

1 / 10
Was this helpful?YesNo
2 Report
  • Bluer...
  • Taken for less than 1 month
  • February 17, 2023

For Bipolar Disorder "This happened a really long time ago, in September 2008 when I was 14. I was recently diagnosed with bipolar and was always angry and crying so I got prescribed this but I only took it a few days because I fell down the stairs! Anyway I had this intense restless cold feeling in both my legs, couldn’t stop moving, I couldn’t keep my eyes open, I gained 45 lbs and I had NO personality. My psychiatrist took me off when she found out what happened to me."

1 / 10
Was this helpful?YesNo
8 Report
  • Madon...
  • Taken for less than 1 month
  • April 5, 2022

"I never commented on a drug even though I’ve been on most of the SSRIs(Paxil, Zoloft, Effexor, Citalopram, Fluvoxamine), Mirtazapine, Ativan and Buspirone, I have never had such bad side effects. I could have died!!! I don’t want to scare anybody because every person reacts differently but even if you have the slightest heart problem (like palpitations, angina) do not take this drug. My doctor prescribed 25mg 3 times a day as needed for anxiety and agoraphobia, I took it for the first time 2 nights ago and cut the pill in half so it was only about 12.5 mg, I woke up with horrible tachycardia 4 hours after I went to bed , it was around 200-250 bpm and had to call 911. I was taken to hospital by an ambulance. I took two ativans on the way (that slowed down my heart rate) I was almost having a heart attack, please don’t start this medication if you don’t have a major problem like schizophrenia, be careful, god bless everyone and hope everybody gets rid of their mental issues."

1 / 10
Was this helpful?YesNo
19 Report

Frequently asked questions

  • Bipolar...
  • Taken for 6 months to 1 year
  • March 14, 2022

For Bipolar Disorder "I had depressive episodes all my life (I'm 55) and was diagnosed with bipolar II about 9 months ago. I have had insomnia all my life, but it became severe and unremitting about a year ago when I became severely depressed/anxious. Started on Lithium and then 25mg seroquel and went up to 100mg seroquel. It never helped my insomnia or my mood and caused constipation. I was on it for about 7 months. Big issue - now trying to get off and having major withdrawal problems. Mild insomnia, excessive sweating, severe abdominal pain. Something new every time I lower the dose by 12mg. I recommend staying on this drug only if you see significant progress. I wish I had been taken off sooner."

1 / 10
Was this helpful?YesNo
11 Report
  • SRRR
  • February 23, 2022

For Bipolar Disorder "THROW THIS MEDICATION AWAY!!! Honestly the worse thing to start.. I’ve been on it for years and now find out it’s caused my pancreatitis. In the past year I’ve been hospitalized 3 times due to it. I’m otherwise healthy and now may have ruined my pancreas due to seroquel"

1 / 10
Was this helpful?YesNo
26 Report

Are you taking this medicine?

  • lalal...
  • Taken for 6 months to 1 year
  • February 7, 2022

For Bipolar Disorder "I once rated this medication highly for my initial positive experience with it. I now believe that is only because it helps me sleep. Once I got up to 200 mg, I felt like a zombie and experienced some other concerning symptoms. When I expressed my concerns I was told that this was a "baby dose" and they intended to still increase from there. I disagreed. I have weaned down to a sleeping aid dose and intend to decrease from there and get off this stuff. It's terribly addicting. When I was at 200 mg I used to experience withdrawal like symptoms if I was accidentally late to take my nightly dose, splitting headaches, shaking. I've seen some say it can be dangerous to not have an exact time each day it is taken, but this was never expressed to me by the psychiatrists who prescribed me. This is not an opiate, but there's a reason some people sell this and call it "baby heroin". If you get prescribed it for sleeping, it did help with that."

1 / 10
Was this helpful?YesNo
16 Report
  • Muffin...
  • Taken for 1 to 6 months
  • October 18, 2021

For Bipolar Disorder "This is horrible with extremely serious side effects. I got anxiety, shaking, face twitching and stuttering like never before. I won’t ever take it again — you cannot pay me enough to get back on it!"

1 / 10
Was this helpful?YesNo
18 Report
  • Survi...
  • Taken for 1 to 6 months
  • October 3, 2021

For Schizoaffective Disorder "1 of the worst meds I've ever taken was only on 25-50 milligrams a day made me extremely tired and my eyes black. I'd wakeup feeling like I was being choked. If I was trying to workout doing push ups for instance I'd get a sharp pain in my head and either my arm or leg or both would give out and I'd fall to the floor almost hurting myself. I thought it was bad for me or I must be allergic to it so I had to refuse to take it anymore after a couple months. I can't believe they are still giving this to people without knowing how destructive it can be to people's lives. It's an older antipsychotic medicine they claim so how could they not know the brutal side effects it causes."

1 / 10
Was this helpful?YesNo
10 Report
  • Anony...
  • May 8, 2021

For Bipolar Disorder "I was prescribed Seroquel 100mg as a mood stabilizer (for Dysthymia and Generalized Anxiety Disorder) by psychiatrist to be taken alongside 200mg Wellbutrin daily. It knocked me out the first time I took it and I noticed my blood pressure dropped sharply, but I felt good in the morning. After 3 weeks I started to feel like a zombie and developed severe constipation, then; suddenly, a feeling of internal tremor, so I contacted my Dr to stop. I slept 2 hours a night for about a week; had horrid nightmares, sleep paralysis, and severe mood swings and panic attacks. I was put on Xanax for the panic, but also developed muscle twitching all over my body that continued at night, waking me up. It's now been 40 days since I stopped taking the Seroquel. My mood is okay, but I still have (slightly less) muscle twitches in the day and night. I wonder if I'll ever be normal again. I'm so angry this was prescribed without explanation, for a minor condition when its effect on me has been far more deleterious to my life than my original condition."

1 / 10
Was this helpful?YesNo
30 Report
  • Evefl...
  • Taken for less than 1 month
  • April 27, 2021

For Bipolar Disorder "This drug is awful. I became a zombie. My muscles began twitching and I felt like I was hit by a truck after taking for 10 days. I stopped it and immediately felt better and actually felt my emotions again. I do not recommend."

1 / 10
Was this helpful?YesNo
17 Report
  • Choco...
  • Taken for less than 1 month
  • January 30, 2021

For Schizophrenia "I was put on this drug in January 2013 when I was 16 and in October 2008 when I was 12. I have schizophrenia and when I first took this back in middle school I don't remember any negative effects but weight gain I ended up being 150 lbs at 5'1 in March of 2009 at age 12 so we stopped it and I lost 17 lbs. in 2013 I was prescribed this and good God I felt awful! I couldn't keep my eyes open at school, I had severe akathisia and was ravenously hungry! I knew it was the medicine because I wasn't dumb so they took me off. I ended up going from 145 to 190 in a damn month all because of this crappy medicine. This, haldol, risperidone and latuda are the worst antipsychotics ever gave to me. I'm on depakote, Zoloft and zyprexa now and no negative side effects except for nausea. Never taking seroquel again"

1 / 10
Was this helpful?YesNo
17 Report
  • Katluv
  • Taken for 1 to 2 years
  • December 24, 2020

For Bipolar Disorder "This medication is NOT GOOD if you have a neurological/movement disorder, and it's neither for anxiety. I have Cerebral Palsy, and I experienced awful spasms, stuttering, muscle twitching, etc. - I wondered if that was Tardive Dyskinesia - but it went away after quitting this medication. My mind was running 100mph, I had random bouts of panic and a much poorer sense of coordination. When I had to unfortunately quit it - cold turkey - I had flailing limbs, shakiness and dizziness. However I have had none of the symptoms with Abilify. It seems that Seroquel is GENERALLY OK if you do not have any neurological issues, but if you do.. STAY CLEAR!"

1 / 10
Was this helpful?YesNo
16 Report
  • ITrus...
  • Taken for less than 1 month
  • December 24, 2020

For Schizophrenia "The first couple of Days I took seroquel, I was more or less a zombie. I was given the drug for multiple suicide attempts because of a severe depression. At day 8 I had the worst manic episode I have ever had in my life, I had no control over what happened and I had trouble breathing. My mild Schizophrenia have since worsened and I experience more hallucinations than I ever have before. This drug is NOT recommended in my opinion."

1 / 10
Was this helpful?YesNo
11 Report
  • Jendo...
  • Taken for 1 to 6 months
  • November 9, 2020

For Bipolar Disorder "Seroquel is terrible. I felt completely disassociated. I knew words were coming out of my mouth but sometimes had no clue what I was saying. I was only on it for a few month but I called my Dr. in a panic when I’d realized the weight I’d gained. I lost 100 lbs in my 20’s and been able to keep it off give or take 10lbs, I’m now 40 years old and I instantly put on belly/waist weight, a place where I have NEVER have gained before. I know my body well & this was pretty extreme. I went up a pant size in 2 months. I told my dr. And he said it makes you crave carbs but I KNOW it’s more than that. What type of meds make you gain weight in a specific area? After loosing the 10-15 lbs, I am stuck with saggy skin after 3 months! It’s not worth it. It created a whole new set of permanent problems like saggy skin & my confidence with undressing around my husband. Horrible!"

1 / 10
Was this helpful?YesNo
33 Report
  • Dusty
  • Taken for less than 1 month
  • November 9, 2020

For Bipolar Disorder "My doctor put me on this medication to help not just my Bipolar Disorder but also for my extreme anxiety and agitation I was having. However, since I am a senior who has had sleep apnea since 1991 and use a CPAP machine every night. I suffer from very bad daytime sleepiness and memory problems. I will NEVER take this again! I was only on 25 mg for two days but I felt like a zombie and very spaced out. My wife almost could not wake me up at 11:00am and it was all I could do to get out of bed. I had to get up since I have diabetes type 2 and need to eat something in order to take my medication. I advise anyone with Sleep Apnea to think twice before you let you doctor prescribe this for you."

1 / 10
Was this helpful?YesNo
16 Report
  • Jenny
  • Taken for less than 1 month
  • September 5, 2020

For Bipolar Disorder "I got very sick and was put into the ICU for a very long time, which caused ICU Delirium and Depression. I had been on Cymbalta, but they changed it to Seroquel. My friends who are nurses make jokes about how awesome Seroquel is for shutting patients up and making them comply. I felt awful on this drug. Leg spasms, drooling, worsened diabetes, etc. They didn't tell me that they'd put me on it. When someone finally told me, I demanded they take me off of it, and the drooling and spasms stopped almost immediately. And I was able to stay awake and think more clearly. And able to participate in physical therapy. I didn't notice any mood improvements and in fact, I was incredibly depressed, but being in the ICU is traumatic, and I had a machine breathing for me, and I was trying to process having almost died. I would recommend trying just about everything else first. I've told my doctors they're never putting me on it again."

1 / 10
Was this helpful?YesNo
101 Report
  • Otto
  • Taken for 5 to 10 years
  • April 17, 2020

For Schizophrenia "I've had a lot of side effects caused by this drug I never knew it was caused by this drug, I had high blood pressure, terrible gas last for days, muscle cramps, seizures I gained 60 lbs or more imbalance drug for 5 years or more I would not recommend it for anybody"

1 / 10
Was this helpful?YesNo
37 Report
  • Elano
  • February 20, 2020

For Bipolar Disorder "I suffer from Bipolar II, take 200mg Lamictal daily, and was prescribed 25mg Seroquel to take at night to help me sleep during hypomanic episodes. My psychiatrist claimed it would calm the racing thoughts, help me fall asleep, and hopefully make me think more clearly during the day. After taking it, I would still be awake for a couple hours trying to sleep and still having racing thoughts. In the morning, I had the worst experiences trying to wake up. I wasn’t trying to wake up early or anything, like 11 on my free days so I could sleep in, and even then I could barely open my eyes enough to turn off my alarm and would immediately fall back asleep. After finally waking up, I felt groggy and disoriented throughout the day. I couldn’t think straight, and was unable to focus during my classes. Not a good experience. I only took it a few times, and decided it was only having negative effects so I stopped taking it."

1 / 10
Was this helpful?YesNo
70 Report
  • Druger
  • February 15, 2020

For Schizoaffective Disorder "Seroquel knocked me out so badly that I slept 18 hours. The heavy sedation effect does go away, though. It did not help at all with my schizophrenia, but it did make me put on a lot of weight. Altogether, antipsychotics have made me put on a ton of weight. I've tried many of them, and I used to weigh 160 pounds and now I am 220. So far, that's all these drugs have done to me, they should be called fat pills."

1 / 10
Was this helpful?YesNo
68 Report
  • Anonymous
  • Taken for less than 1 month
  • December 1, 2019

"Stay away from this seroquel if you have any sort of epileptiform activity in your brain! Epileptiform discharges mimic psychosis and rather than giving someone an anti psychotic they treat it with an anti convulsant. Seroquel makes the epileptiform discharges worse so you may have hallucinations. It happened to me. It’s a bad drug for epileptiform! Horrible! I took it for insomnia because I was so sleep deprived."

1 / 10
Was this helpful?YesNo
17 Report
  • Salty...
  • Taken for 5 to 10 years
  • October 23, 2019

For Bipolar Disorder "After three days I had started having suicidal thoughts so had to go into hospital for seven days. I now take Effexor 150 and Lamictal 100"

1 / 10
Was this helpful?YesNo
22 Report
  • Anonymous
  • Taken for less than 1 month
  • October 16, 2019

For Bipolar Disorder "Seroquel was drug ever for me, I had sleep paralysis on it. I even hallucinated after taking it."

1 / 10
Was this helpful?YesNo
14 Report
  • Rhianon
  • Taken for 2 to 5 years
  • September 22, 2019

For Bipolar Disorder "THIS WAS MY EXPERIENCE... I have been fighting mental disorders since age 14. During the 40+ years. I have been prescribed tricyclics, typical antipsychotics, SSRIs SNRIs Benzos (diazapam when 16 years old). I chemically blew out my brain, specifically the serotonergic and dopaminergic pathways, by doing LSD from 1978 through 1981. It was the '70's. So now at the edge of 60, I have horrible reactions to psychotrophics. Seroquel paralyzed my arms and legs after my nightly 1 to 3 hours of sleep, such that I had to lay there until I could use my left arm to pick up my right arm, then with both free, I used them to get my legs going. I took it for about 4 years, with the above side effects plus the helicopters whizzing through my brain and body. To me, it is a nasty drug. I finally got sick of it. tossed the remaining pills, went loopy. My partner thought I was going to die. I lived."

1 / 10
Was this helpful?YesNo
42 Report
  • Anonymous
  • Taken for 10 years or more
  • August 9, 2019

For Bipolar Disorder "This medicine is ruining my heart, been on it for ten years and now have heart problems and constant chest pain...wasn't informed there's a blackbox warning"

1 / 10
Was this helpful?YesNo
47 Report
  • Missy
  • Taken for 1 to 2 years
  • July 4, 2019

For Bipolar Disorder "Seroquel has made my life a really bad and made me gain 100 lbs"

1 / 10
Was this helpful?YesNo
30 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.