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Quetiapine for Generalized Anxiety Disorder User Reviews (Page 4)

Brand names: Seroquel, Seroquel XR

Quetiapine has an average rating of 7.4 out of 10 from a total of 190 reviews for the off-label treatment of Generalized Anxiety Disorder. 66% of reviewers reported a positive experience, while 16% reported a negative experience.

Reviews for Quetiapine

  • BanSe...
  • January 18, 2012

Seroquel XR (quetiapine) "SEVERE WEIGHT GAIN and METABOLIC SYNDROME! I had always suffered from anxiety from childhood to adulthood. My doctor prescribed a low dosage of 150 MG in December 2010, At the time I was prescribed Seroquel XR 150 MG, I weighed 96 lbs, petite frame, size 0 or 2. On January 11, 2012, I weighed in at 136 lbs. The 40 lbs of weight gain within one year went to my abdomen and I am covered in cellulite on my abs, hips, back, buttocks and thighs. I monitored my diet and intake the entire time, but the weight gain was out of control."

1 / 10
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69 Report
  • dvws
  • April 20, 2012

"My Doctor started me on quetiapine after I had been having anxiety and panic attacks. The first few days I felt real groggy and they sure make you sleep well. I haven't had any side effects like I did with antidepressants. I just hope they work for me."

6 / 10
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  • cobweb
  • July 2, 2018

"50 mg helps neutralise a Borderline Personality Disorder, anxiety and paranoid episode. I find in this state it does not make me sleep, but rather calms me enough to not act in a rash, impulsive manner, and helps quieten my irrational thoughts."

10 / 10
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40 Report

Frequently asked questions

  • Bill
  • November 29, 2018

"I have struggled with extreme anxiety and depression for over 15 years. The first several years were conventional treatment of Paxil and Serax, a benzodiazepine. Unfortunately, benzos are extremely addicting and extremely dangerous to quit without help. I reached a crisis point around 8 months ago where everything seemingly stopped working all at once. The benzo treatment had reached the end of it's usefulness and was now causing anxiety instead of easing it. This was when my doctor prescribed low doses 12.5-25 mg. 1-2 times a day of seroquel to augment my Paxil. I am not going to rave about it, but it is an alternative for those who are slim on options. My Dr. says it is non habit forming, but until I see it myself when I try to discontinue them, I am wary of this claim. It does work very well in helping intense anxiety and fairly well for depression."

7 / 10
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  • AshHon
  • Taken for 1 to 6 months
  • August 9, 2018

"Hi I started on 25mg of quetiapine in morning and night for anxiety. It was not doing much last week so I got put on three 25mg daily !! Tuesday of this week I was in so much panic and nerve damage pain he has put it up again to 50mg 3 times a day!! Now I can't sleep feel confused and spaced out!! I am a single parent of a 7 year old daughter and I now feel like a vegetable!! Does anyone else out there have any ideas please???"

7 / 10
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Are you taking this medicine?

  • MissL...
  • June 30, 2018

"I wanted to update my review for Seroquel in the use of treating my GAD. My former GP prescribed Seroquel XR 50mg for anxiety and I found that it made me a zombie - I felt completely disconnected and wanted to sleep all day long. However, my psychiatrist recommended using the regular version instead and prescribed Seroquel 50mg normal release. It has made such a difference in the way I feel! Granted, I do still have periods of fatigue, but nothing like the XR version. I'm able to function normally most of the time. It is a lifesaver!"

10 / 10
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  • hahaha
  • Taken for 1 to 6 months
  • May 3, 2017

"I was diagnosed with bipolar disorder and Generalized anxiety disorder in a residential treatment center. I was dependent on 4mg of klonopin a day, and when I started to taper off the panic attacks and lack of sleep was so UNREAL. My doctor put me on seroquel 25mg twice a day and 50mg at night time. It makes me really tired so it helps me sleep. I used to wake up groggy, but not anymore. overall, great medication. I'm now on 50mg a day as needed, and 50mg at nighttime. Seroquel REALLY helps my panic attacks. The dose I'm at doesn't make me as tired as it used to. I'm on remeron at night time so the two really knock me out. Overall, great medication. Only side effects: bad dry mouth, sleepiness"

9 / 10
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  • Roxy
  • Taken for less than 1 month
  • June 11, 2019

"Just started quetiapine 3 nights ago for Generalized Anxiety. So far I haven't been in any anxiety situations so not sure if it works or not. The first 2 days I was a zombie in the day even after 9/10 hours sleep. I am only on 12.5mg at night. Hopefully it works as I was on Wellbutrin for 4 weeks and that stuff was horrible for me, it gave me the worst anxiety where I was downing ativan daily! Which I never do as my anxiety isn't every day. I go back to my doctor next week to report in if it is working or not. Fingers crossed it does it's job !!!"

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  • Emily
  • Taken for 1 to 6 months
  • January 19, 2021

"I was on this drug for about 2 months. It never cured my anxiety or depression. I'm very sensitive to medication side effects, so I started on only 6mg and went up to 12mg. It helped me sleep which was nice, but made it difficult to wake up in the morning. The longer I took it, the more I noticed the side effects, they seemed to be getting stronger. I felt weak and sick before lunch, like it was interfering with my blood sugar levels, eating helped this. I often felt light headed. Straight after taking the medication at night, I felt like it was making my heart race, towards the end it was also giving me chest pain, that's when I stopped taking it, I was scared of having a heart attack. The drug never made me feel any better. As soon as I stopped the drug, I felt like a weight was lifted off me, I felt so much more calm and happy! Turns out the medication was making my anxiety and depression worse! I didn't realise. So happy to be off it."

1 / 10
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  • Mano
  • Taken for 1 to 6 months
  • November 4, 2019

"I had originally taken 150mg seroquel as a mood stabilizer for Bipolar 2 about two years ago. Adjusting to the medication was terrible, as I had gained about 10 pounds, was groggy for hours after I had waken up, and got restless legs. I had stopped taking it due to these effects. Days ago I was prescribed a low dose of 25mg just for sleep and anxiety. The first two nights taken it I got extremely tired within 30 minutes, woke up multiple times throughout the night, had sleep paralysis, and woke up groggy once again. The third night is when I decided not to take it and even after only two nights of it I was still not able to fall asleep for the life of me! I do not recommend this medication as one may become extremely dependent on it and need it for the rest of their lives!"

2 / 10
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  • Kat
  • July 19, 2016

"I've been using seroquel 25mg 4 times per day as needed since September of 2001 and it is still very effective with both my anxiety and depression. I did gain about 10 pounds using it, but I am still well within my BMI range and am physically active and can control my appetite. This med is possibly the best one that has ever been prescribed to help both my anxiety and long history of depression. My one important concern is that my white blood count is slightly lower than it should be and has been lower for 6 years now. I'm hoping my white blood count does not drop lower and stays where it is."

9 / 10
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  • Drexc
  • Taken for 2 to 5 years
  • November 26, 2015

"After trying different medications, seroquel 50mg just changed my life. It is quite sedative but i do a lot of sport as well and have a lot of energy. Iam stable since 3 years with seroquel. Life saver"

10 / 10
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  • My...
  • Taken for 2 to 5 years
  • August 20, 2016

"Seroquel gets rid of 95% of my anxiety and severe insomnia. I've tried everything else. I don't feel drugged. I just feel something like a normal person. Its amazing. It only got rid of about 30% of my depression, but together with with Lamictal they cover 80% of my depression as long as I make sure to stay social. I take 350 mg about 2 hours before bed. It was EXTREMELY sedating at first, but within a month (maybe 2 weeks), I adapted to each new dose increase. I do have to make sure to get 8-10 hours of sleep every night, but a big part of that is my CFS and sleep apnea. We slowly went up over the course of 3 months to get to 300 mg. And after being on it about 2 years, I had to raise it to 350 mg because it wasn't working as well."

10 / 10
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  • DonAl...
  • Taken for 2 to 5 years
  • July 27, 2017

"This medicine has been just wonderful for me. I have been diagnosed with bipolar disorder and an anxiety disorder. It really calms my racing thoughts and smooths me out. I have been on many different doses, all of the way up to 800 mg. I don't know why Dr's sometimes insist on overkill. Anyways, the magic dose for me is 200 mg at bedtime. It keeps me calmed down, and my anxiety stays in check all the next day. I have been taking it for three years and I don't get the brain fog or sleepiness effect anymore. I use 10 mg of Ambien to help me sleep. It does okay, but the combination doesn't "knock me out" like it does some people. Overall, Seroquel is great for me, but it is very rough on others. it is worth a try at least."

9 / 10
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  • Tedium
  • December 24, 2016

"Prescribed by shrink for insomnia and anxiety when was having a terrible time trying to get off benzos. Has worked very well albeit I have stuck on same dose of benzodiazepines on advice , ie not come down any more. It's great for going to sleep and not waking up at 4 am worried about stuff. Yes it makes you a bit drowsy and you do eat more . It reminds me of the munchies. Best thing is just to go to bed. I wanted to say though that the dose is critical. For sleep dose very low. I take 12.5 mg . I went up to 25mg and was a zombie it was horrible. If you have a shitty time try halving t he dose. I know it does different things at different levels and maybe if you took a whole lot more then it would work in a different way ."

8 / 10
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  • choco...
  • Taken for 5 to 10 years
  • August 11, 2022

"I was first prescribed the IR form in 2017, and didn’t realize how much it helped with my anxiety and depression until I tried to go off of it in late 2021. I thought it was only really treating my insomnia, and it’s not recommended for that, so I asked my sleep specialist to switch me off of it. After 7 terrible months, my IOP psych was the first psych who informed me that Seroquel is often used off-label for anxiety, and this use is even supported by peer-reviewed research. I agreed to try it again, and the difference was obvious almost immediately! Looking back, it was also the best med for my depression. Although it’s only approved as an adjunct, I was on just quetiapine for a few years with no issues. I take 100mg IR every night, and it helps manage my anxiety, narcolepsy insomnia, and MDD with no side effects. Tackles 3 issues with 1 pill. You can’t ask for much better than that!"

10 / 10
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  • Jabba
  • Taken for 1 to 6 months
  • October 30, 2023

"Adult female, taking this medicine off-label for Generalized Anxiety Disorder, for CPTSD from severe traumatic events I experienced in my childhood and throughout most of my adult life (sexual violence), and for ADHD. It helps me sleep and gets rid of repetitive and recurring thoughts as well as extreme emotions I deal with daily, enough to help me focus on other tasks. I’m less argumentative, not emotionally numb but less affected by what others say and do, and able to see things as they are. Highly recommend. It’s not addictive and the benefits outweigh the side effects for me at 25 mg. Side effects include bloating, constipation and fatigue but eating healthy and exercise helps. I also have low appetite. Previously was prescribed SSRIs (escitalopram, sertraline) and benzos (Klonopin, Xanax) by other docs, which made my anxiety much worse, and not better. Quetiapine is a good alternative for me."

9 / 10
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  • SAM
  • Taken for less than 1 month
  • September 11, 2023

"I have suffered with what i now know is severe GAD and panic disorder - once before i landed in hospital and had a very negative experience with whatever meds they put me on. it went away and this year came flooding back - I got perscribed urbanol for short term use and then when it got worse (not due to urbanol) i got perscribed dopaquell 25mg at night which is the same as serequell... I have not yt built my way up to 50mg maintenance dose - i am a fearful person when it comes to it seen as its an anti pshycotic and that scared me so badly I am now on day 11 - i have had maybe 1 and a half panic attacks in this time - granted though i spun myself out in fear.. I CAN say that i have noticed I am calmer I am not so OCD about everything I can actually sit and chill which if u ask my husband I NEVER EVER DO.. I do not over or under react and if i DO get angry or anxious it seems a bit easier to cope. I have def seen improvement and I am hopeful for a future of no anxiety and panic"

9 / 10
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  • Rach
  • Taken for 1 to 6 months
  • January 23, 2022

"I've been on this medication for roughly 3 months and take 30mg every night. It has completely transformed my life and for the first time I feel stable and in control. I'm 23 years old, have a diagnosis of c-PTSD and generalised anxiety, and have had relatively regular panic attacks from around 16 years old. I used to get into a very heightened emotional state very easily, would regularly freeze up and become incredibly dissociative for hours on end, would be very nervous out in public, near crowds and in noisy areas. With the exception of some people in my life, I believed I fundamentally could not trust most people, I was very sensitive to (perceived) changes in other people's emotional state and I was incredibly hypervigilant around men. I also used to struggle to fall and stay asleep and was incredibly sensitive to being touched, to the point it sometimes felt uncomfortable or even distressing. Now I am immensely more settled and able to employ what I've learned in therapy."

10 / 10
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  • VUser
  • Taken for 1 to 6 months
  • June 5, 2013

"I've been on quetiapine XR 50mg for almost 2 months mow and it's been great, no anxiety and my head is clear. HOWEVER, I have missed one dose of it once and started having bad heartburn with constant feeling of hunger and I think it's because of that. So, I will probably stop taking it, although I really don't want to."

10 / 10
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  • Anon
  • Taken for 6 months to 1 year
  • January 4, 2022

"This is an interesting medication. The first 2-4 weeks can be tricky. I found that it does have a sedative effect and was amazing for sleeping. It did also make me agitated/jumpy if I took a higher dose (weirdly paracetamol or ibuprofen lowered this effect). Can be helpful to try a lower dose and see the difference. I did feel foggy and had trouble concentrating the first month. Your body does need to get used to it, then I saw major improvements in mood and reduction in depression and anxiety. It is good because it immediately reduces extreme anxiety (compared to SSRIs and SNRIs) and then kicks in to help over the longer time. I would use in conjunction with working with a psychologist. If you're going through anxiety or depression this medication is a much better option to benzos or SSRIs or SNRIs."

9 / 10
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  • Julie...
  • Taken for less than 1 month
  • July 18, 2019

"I was prescribed Seroquel 50 mg XR, one pill at bedtime to augment my antidepressant. I only took it for three nights in a row. The anxiety was unbearable after taking the medication. I slept throughout the days and forgot appointments, forgot to take other medication, forgot to eat. The only moments I could keep my eyes open I was in panic. Horrible drug."

1 / 10
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  • Krist...
  • June 25, 2018

"Suffered severe panic attacks and general anxiety on and off for months. Life was horrible to say the least. Tried increasing my antidepressant dose (cipramil), but no effect. Doctor suggested Seroquel XR, 50mg each night. Worked well but was still getting anxious spells. I increased to 75mg, and have had a week without panic. I'm able to work, enjoy things and feel more optimistic about the future. I feel a bit tired an fatigued, but I have recently been diagnosed with anemia, so I think this plays a huge role. Other than that: no side effects. Love this drug!!!!"

9 / 10
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  • Seb
  • Taken for 2 to 5 years
  • August 2, 2019

"It works to reduce obsessiveness and anxiety but has made me go up two dress sizes which is horrible and I HAVE to stop taking it but now I'm lowering my doses the obsessiveness is back. I have been diagnosed with GAD not OCD because I don't have compulsions but only obsess on things."

5 / 10
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  • Waler
  • Taken for less than 1 month
  • January 27, 2023

"I am unfortunately experiencing postnatal anxiety also said to be a severe anxiety disorder which is quite literally consuming me. I was put on Quetiapine 25MG (one in the morning) to help with ruminating and intrusive thoughts. Before taking the drug I did my research and read many reviews, I was very reluctant due to negative reviews, I decided to give the drug a go as everyone is completely different and as I said before the anxiety was completely consuming me, however, this did NOT help, In fact made everything worse, I couldn't function! The anxiety was at its worst, I was like a zombie! I was dizzy, lightheaded, couldn't think straight, very emotional and if anything made me not want to live. I will NEVER touch this drug again. It was horrendous. I was only on this drug for 2 days before having to stop it, I know you are supposed to hold tight and give the drug chance to work but no way could I have continued to feel how I did. Good luck to everyone on their journey."

1 / 10
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11 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.