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Quetiapine for Generalized Anxiety Disorder User Reviews (Page 2)

Brand names: Seroquel, Seroquel XR

Quetiapine has an average rating of 7.4 out of 10 from a total of 190 reviews for the off-label treatment of Generalized Anxiety Disorder. 66% of reviewers reported a positive experience, while 16% reported a negative experience.

Reviews for Quetiapine

  • mutley
  • Taken for 5 to 10 years
  • January 3, 2017

"I can honestly say that quetiapine has saved my life. I take between 25mg during the day and 50mg at night. Anxiety is a wearing experience, like a caterpillar gnawing away at your well-being in an endless cycle. I have been on it for about 7 years now, and I was prescribed it by a one-time visit to a psychiatrist at the surgery. The winter months with the dark nights here in the UK can be unremitting, but this little pill does so much and is not addictive. If you're in doubt, go for it... although all drugs work differently for everyone."

10 / 10
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107 Report
  • star
  • September 28, 2013

"This medication has significantly reduced my anxiety. I am currently on 50 mg and I am able to sleep longer without midnight interruptions. Before Seroquel, I took 10 mg of Abilify (bad lethargy and restlessness). Life doesn't seem so scary to me anymore."

7 / 10
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138 Report
  • ariel...
  • April 15, 2016

"I found Seroquel to be the wonder drug for my anxiety problems (due to long-term drug use). I was prescribed it five years ago at 100 mg a day. That has decreased to 50 mg at night, but I have since made the decision that I am ready to decrease this further to 25 mg a day, then down to none, as I have been free from addiction for the past five years I have been taking Seroquel. In my mind though, I would never have gotten through the debilitating anxiety that followed without the help of Seroquel."

10 / 10
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111 Report

Frequently asked questions

  • Sax
  • Taken for 6 months to 1 year
  • August 23, 2016

"I have been an active drug user my whole life, and I was diagnosed with psychosis and an anxiety disorder. I highly recommend this medicine for psychosis. Within two weeks of taking it, I felt my brain chemistry changing, and it's currently changing my life for the better each day. Works well for anxiety too; it calms my nerves down and puts me to sleep. Don't know where I'd be without Seroquel :)"

10 / 10
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102 Report
  • baske...
  • Taken for 1 to 6 months
  • April 2, 2014

"I was diagnosed with severe generalized anxiety, mood instability, and had pretty bad insomnia, where I would wake up mid-sleep approximately 4 times a night. I've taken Cipralex (20mg) for a year, and I've been on Seroquel (25mg) for about 5 months, and I find that I'm able to think more clearly and act less impulsively. With my anxiety, the physical symptoms have decreased quite a bit, though mentally, I am in control of my thoughts. As for sleep, I sleep a solid 8 hours a night, usually undisturbed. I did experience a bit of weight gain though (10-20 pounds)."

7 / 10
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119 Report

Are you taking this medicine?

  • MrTon...
  • July 14, 2018

"This medicine gave me my life back, by actually controlling anxiety both physically and mentally. For me the only side effects have been weight gain and heartburn, both of which I will gladly take for the freedom it has given me from my anxiety. No more panic, no more worry, no more racing thoughts, and I can think clearly and logically again. It does not make me sleepy like my doctor said it might, but instead just relaxes me enough that sleeping is possible once again. The nighttime need for snacking is kind of annoying, but I'll take it and the freedom this medicine has given me over the crippling anxiety!"

10 / 10
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76 Report
  • No re...
  • Taken for 6 months to 1 year
  • October 27, 2021

"I would have panic attacks everyday and my anxiety really manifested itself as nausea and vomiting. After trying 3 other medications and having continued anxiety/vomiting I was prescribed seroquel. Within a week my life was changed. I stopped having anxiety and throwing up. I finally put on some weight and people stopped commenting on how sick I looked. I am so happy with this medication it brings me to tears. My life was so miserable before it."

10 / 10
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39 Report
  • Long...
  • Taken for 10 years or more
  • March 29, 2015

"Been on Seroquel for 10 years along with Celexa. It's a lifesaver! Anxiety and depression are manageable. I feel normal. The only issue is the weight battle. But I would rather be overweight than thin and depressed or worse."

9 / 10
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97 Report
  • Jac
  • January 24, 2015

"I've been on Zoloft for 7 years. I experienced my first panic attack about 2 years in. Since then it had gotten really bad, so much that I was having 3 or more a week. I was given quetiapine by a psychiatrist. He recommended half a tablet (tab is 25mg) so 12.5mg morning and night, but to start taking it just at night to see how I go on it. The first night I slept about 11 hours. The next night was 8. It sorted itself out after that first night. I still do not take it in the morning as I don't want to be drowsy at work. As far as the panic attacks go, I've been on it for 2 months now and I've only had one. I've been able to accept a promotion that has me work 6 hours from home for a few weeks. I have my life back!"

9 / 10
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98 Report
  • Anonymous
  • April 13, 2012

Seroquel (quetiapine) "My doctor prescribed Seroquel for a number of psychiatric conditions I have. They are: Depression (already on 40 mg Celexa for this, Seroquel helped as an add-on), OCD, Generalized Anxiety Disorder, anorexia, and mood instability. Seroquel helps with all these conditions, although it causes moderate constipation."

8 / 10
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  • jamal...
  • Taken for 1 to 6 months
  • January 7, 2024

"I am prescribed a low dose of Quetiapine (12.5 mg - 25 mg) off label for severe anxiety, PTSD, and depression. Quetiapine gets rid of most of my daytime anxiety and panic and helps me sleep at night. My anxiety and panic had gotten so bad that I started hearing voices and seeing things that weren't there after a terrible experience on SSRIs and a really bad therapist. I started hallucinating and experiencing flashbacks from childhood molestation, as well as decades-old sexual assault and rape. Quetiapine to the rescue. This antipsychotic really works wonders for me. Without this med, I very likely wouldn't be here right now writing this comment. I highly recommend it."

9 / 10
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  • Anonymous
  • November 26, 2010

Seroquel (quetiapine) "After trying nearly every SSRI on the market, I was placed on Pristiq, which improved my condition somewhat, but still left me dependent on Xanax to alleviate my daily anxiety. After a particularly bad stretch, I was also placed on Seroquel XR. It has helped more than I could have ever hoped for. I finally don't have to reach for Xanax as soon as I wake up. It was very sedating for the first week after I started and after increasing my dosage, but this has lessened with time. I do make sure to take it before bed, as it does make me tired as it kicks in, but I welcome this due to my problems with insomnia."

9 / 10
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124 Report
  • June
  • Taken for less than 1 month
  • January 24, 2020

"I was prescribed 25mg of Quetiapine as an alternative to Valiums to treat my recent worsening anxiety and I can honestly say that I have never felt worse in my entire life. I’ve only been on it for FOUR days and have already experienced brain fog and really dark thoughts. I have however noticed that it helps ‘contain’ my anxiety but to an extent where I feel nothing that it’s making me more depressed. I don’t know if it’s normal to feel this way after less than a week of taking this medication? I’ve previously been on Mirtazipine around a year ago, and Quetiapine gives me similar effects such as weight gain, suicidal thoughts, depression, brain fog. I’m returning to my doctor to make a note of that and will never go near this medication ever again."

1 / 10
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53 Report
  • Anonymous
  • Taken for 5 to 10 years
  • August 14, 2016

"I cannot rate seroquel highly enough. I was a mess with constant anxiety that just would not stop. I had tried so many things and seroquel literally changed my life. I take 400 XR and don't really have any side effects, but even if I did, I would put up with anything to be rid of the anxiety. I don't know how I managed to get through life before I started taking seroquel."

10 / 10
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80 Report
  • Rose
  • Taken for 1 to 6 months
  • November 19, 2022

"This medicine literally saved my life. All I can say is I have been battling with anxiety for as long as I could remember at one point I was dealing with a severe depression and extreme and anxiety with insomnia. I literally tried all the anti-depressants that you could name and non them seem to be working I gave up hope on medicine in general also I come from immigrant families so I’ve never had anyone in my family who has relied on medication. And definitely battling my own personal stigmas as well as cultural stigmas about medication for mental health. All I can say is nobody wants to take medication I got to a point where it was begging to overpower me it was overpowering my life with my sleep and everything . I remember taking this medication and actually feeling normal. No more intrusive thoughts. I could actually sleep at night. At first the side effects were pretty annoying such as oversleeping a little drowsiness and tiredness but trust me it’s gets better."

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24 Report
  • rsf
  • August 21, 2016

"I take Seroquel 50 mg and Jovia at night for 7 months already. These meds made me happy and free from my GAD. They cost a lot, but they are worth it. I don't gain weight because I don't eat a lot of carbs and sweets. Thanks for the happiness I feel. =)"

10 / 10
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77 Report
  • Cat
  • Taken for 2 to 5 years
  • December 13, 2020

"I was on a benzo for 20 years was not told to take it when required. I took daily. Tapered off the benzo which took me 2 years of nightmarish withdrawals...I now take quetiapine 25 mgs at night. And half of a 12.5 prn. It helps and is not as addictive as a benzo for anxiety. It is what it is for me."

8 / 10
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42 Report
  • sjm
  • Taken for 1 to 2 years
  • April 27, 2015

"While this medication hasn't solved everything, 50mg every night has helped me get some of my life back. My anxiety was so bad that I couldn't eat or work. This has really helped with the more 'mental' symptoms of anxiety, whereas other medications mostly just helped with the physical (sweaty palms, tremors, chills). It has also helped me sleep tremendously, though I do have some trouble getting up in the morning. No other side effects."

9 / 10
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85 Report
  • Happy...
  • October 19, 2010

Seroquel XR (quetiapine) "I was on Seroquel for two years and loved it except at the beginning I was very sleepy, but it went away after a few weeks. I was very shaky, but other than that, it was wonderful. I am drug-free and loving it today; easy to go off it too."

10 / 10
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112 Report
  • Bnewton
  • Taken for 1 to 2 years
  • July 13, 2018

"I have been on this drug twice. The first time I ended up overdosing but bear in mind, I was doing drugs while my body was still getting used to the medication and I was young and stupid. Second time round, absolutely no worries. Prescribed 50mg at night but I only take 25 now, somehow my tolerance decreased and 50 made me a zombie. This drug saved my life. It is the best medicine ever, and this is somebody who reacts badly to medication usually. I have been on it for 18 months continuously now for anxiety, insomnia and as a mood stabiliser. No side effects except a good night's sleep and hunger (which I need). Good luck with this medicine. I truly owe my life to it."

10 / 10
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60 Report
  • Alexa...
  • Taken for 1 to 6 months
  • August 23, 2015

"Seroquel has been pimped out by Astra Zeneca as some kind of wonder drug when in fact it is messy, highly sedative, and possibly life-threatening. This medication acts on pretty much every receptor, even histamine. It doesn't really seem selective at the least when you analyze it's affect on the brain. This 'medicine' dopes you up more than any drug I've seen. Even heroin addicts have more energy and ambition. It simply is an all around slowly poisoning anyone who takes these horse tranquilizers; they turn your brain to mush! Get off them as fast as possible. I was lucky to be able to quit with very little adverse effects."

1 / 10
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80 Report
  • ekech
  • February 14, 2020

"It worked really well for my generalised anxiety and disassociate disorder, made it manageable. But even on a low dose it has made me pile on the pounds. I've put on 2 stone. I was on 100mg dose and managed to reduce to 75mg because of the weight gain. I am trying to get off it because of the weight but its very hard. The withdrawal symptoms are quite strong, can't sleep at all without taking it and they don't seem to get better with time. I tried a week with no sleep, so going to try VERY gradual withdrawal."

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47 Report
  • sarah...
  • Taken for less than 1 month
  • April 26, 2021

"I have severe anxiety (GAD, SAD, OCD, Panic Disorder, Agoraphobia), and was prescribed this as a when required medicine. When I visited the hospital for worsening panic attacks. I was given this, and the psychiatrist straight up told me that the goal was to make me too tired to be anxious. My instructions were to take 12.5 mg twice per day (morning/night). I don't know why, but I guess this is either stronger than all the other psych meds I've tried, or I'm sensitive to it somehow. I couldn't attend school because I was so tired constantly, I slept for I think 16 hours straight, but the quality of it was absolutely terrible- nightmares, sweating, frequently waking up and then falling back asleep. Also it gave me constipation. I take trazodone every night as well, but both these meds are at a low dose so the doctor wasn't concerned. I don't know. It's certainly not for me, but it does wonders for others!!"

2 / 10
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37 Report
  • Lilac
  • Taken for 1 to 6 months
  • July 31, 2023

"After a lifetime of depression, anxiety, and mood swings, this medication has finally been a godsend. I’ve tried many antidepressants and a number of antipsychotics, but quetiapine is the only medication to calm me enough to be able to think clearly and make non-emotional choices. I take half a tablet (a tablet is 25mg) in the morning, half a tablet at midday, and a whole tablet at night. I don’t feel tired on it, just calm - it’s like my brain is clear of emotions so I can think without reacting."

10 / 10
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15 Report
  • Ms Br...
  • July 5, 2011

Seroquel (quetiapine) "I've been using Seroquel now for 4 years. I suffer from anxiety and can't sleep at night. Seroquel has helped me sleep and helps me throughout the day with my anxiety. If I feel anxious, I take a 25mg pill, and it alleviates the anxiety for me. I think it's very good for both. It has helped me tremendously."

9 / 10
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99 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.