Compazine User Reviews & Ratings (Page 4)

• MadPi...
• February 10, 2018

For Nausea/Vomiting "I went to the ER with a migraine and I got this through an IV. I was totally fine and all happy until this drug hit me. I went completely insane. I got claustrophobic, I wanted to kill myself, I started twitching, and I got super anxious. They gave me some Benadryl which helped so they sent me home. On the way home it happened again, and it kept happening all night even after I kept taking Benadryl. The only time I felt not insane was when I was sleeping but I was still having weird dreams. The next morning I woke up and I was still really anxious but the serious side effects went away. For 2 more days I still felt anxious and it was the worst thing ever. Everyone told me this was really rare and I don't think any of the people there at the ER really knew what was going on. This is a scary drug. I just wanted to share my story."

• NE603
• Taken for less than 1 month
• February 1, 2019

For Nausea/Vomiting "I had experience high agitation and restlessness with this drug before so it’s been in my allergy list, unfortunately I was going through a difficult procedure and it’s the only anti-emetic this office offered. It had been over 10 years since I took it so I figured I’d try it again. Bad idea. This drug causes severe anxiety, agitation, muscle pain and a general feeling of needing to rip out of your skin!! I remember now why it was on my DO NOT USE list, the affects stay with you for a long time too. I will never take this again.. there’s a reason it’s listed as a mental health drug/antipsychotic.. IMO it MAKES you psychotic."

• saaaa...
• February 21, 2016

For Nausea/Vomiting "Went to the ER twice with a severe migraine, both times given Compazine. It definitely helps with relieving the pain but the side effects out weigh it for me. Felt like my skin was crawling, restlessness, skin rash, dry mouth, anxiety (triggered a panic attack both times), brought up a lot of bad thoughts of how I was dying. Long term, rebound headache, insomnia, loss of appetite. Also had it with Benadryl once and that scared me."

• Marie
• June 7, 2018

For Anxiety "About a year ago I went in to the ER for nausea and headaches they gave me Compazine through my IV almost instantly my heart was racing to the point I almost passed out I was screaming for help. How does one get over the fear of taking medicine once something like this has happened to them?"

• Birdie
• Taken for less than 1 month
• August 23, 2020

For Nausea/Vomiting "Went to the ER with extreme dizziness. They wound up giving me Compazine. I wasn’t even familiar with what it was. I felt strange at first, but then my hands contorted & froze. My mouth had almost completely clamped shut. An orderly or a CNA just happened to come by to empty trash. I barely was able to say please go get someone something’s not right. The dr at first thought I had stroked. He ran some test gave me some Benadryl which helped. I would never take this drug again."

• anony...
• November 29, 2018

For Nausea/Vomiting "My mother had a colonoscopy and had a vocal chord spasm which caused her to cough during it. They gave her some medicine (don't remember the name) to help dry up her secretions and calm down the coughing. This made her chest tight, painful, and made her feel nauseous after she got home. I took her to the ER, she is allergic to Reglan, so they gave her a mix of benadryl and compazine for nausea. Within 5 minutes she was jittering around and felt like she wanted to rip her IVs out and run home. Her anxiety skyrocketed and her heart rate went up to 154 bpms. It wasn't until they gave her Ativan that her heart rate went down and she was able to calm down. We got sent home & she was still anxious and fidgeting around for about 4 hours until she finally fell asleep. She woke up and still felt a little anxious & fidgety but not near as bad as last night. One of the worst experiences she & I have ever had and she is going to have it put as she is allergic so she never has to be through it again."

• Ruth
• Taken for less than 1 month
• November 29, 2018

"I went to the ER for a migraine and was given this medication combined with benadryl. It basically induced a panic attack and I felt as if I couldn't breathe properly. It was awful especially as I wasn't anxious about being in the ER, but after taking compazine I just wanted to leave."

• Nana...
• August 2, 2016

For Nausea/Vomiting "I was taking zofran for years for severe nausea. During a hospital stay I was given Reglan and had horrible hallucinations and my skin was crawling like some people in the reviews had with Prochlorperazine. However Zofran stopped working for me during the last bout of nausea so my doc gave me Prochlorperazine which helped tremendously and thankfully I had no side effects."

• Nathan
• Taken for less than 1 month
• April 29, 2023

"I went to the ER with the worst headache of my life. After a spinal tap, the doctors determined I had encephalitis. The pain I felt from that and the spinal tap were bad enough, but even that wasn’t as bad as the pure dread that Compazine made me feel. Prior to administering it, my nurse warned me that some people can have a bad reaction to the drug, but she said Benadryl typically counteracted those negative side effects. I wish I’d had the sense to ask more questions first! Within five minutes of taking it, I felt like I needed to crawl out of my own skin. I’m a pretty calm person with a good grip on my emotions, but I felt like a lost all control in that moment. I screamed at my nurse and told her to get it out of me. Knowing now that they could’ve given me Ativan to calm me down irritates me a little because they made me lay there and suffer through it for hours. Luckily, the side effects didn’t last more than a few hours, but it felt like an eternity."

• Babyj...
• Taken for less than 1 month
• October 22, 2018

For Nausea/Vomiting "I'm just getting this medicine for a headache cocktail. And let me tell you I wanted to jump out of my own skin I have never felt anything like it it was absolutely horrible do not let them give you this medicine especially if you have anxiety which I have and they knew that because I told them absolutely horrible like your legs have bugs all in them and they're just crawling everywhere never ever again!!!!"

• Usles...
• April 6, 2019

For Nausea/Vomiting "I was given a migraine cocktail that had compazine included in it. THIS MEDICATION MADE MY SYMTOMS A MILLION TIMES WORSE! I started with my heart pounding and a severe anxious feeling immediately. I was given this med thru an IV. It literally felt like an instant panic attack. It's been 4 days now and I still am having spontaneous bouts of anxiety due to this medication. The half life is 24 hours with this med and it's been well over 96 hours since I was administered it and I'm still experiencing side effects. I also got low blood pressure which gave me cold sweats, disorientation and I was freezing. My only relief was from hot baths which made my blood pressure go up some. I also had dissociation, as if I wasn't even myself, from this medication. I can not stress enough how awful this medication is and it should NOT be used as nausea relief unless it's for EXTREME circumstances. This medication is used in people with schizophrenia! I am still not myself days after and its miserable."

• NoGut...
• February 7, 2020

For Nausea/Vomiting "I was given Demerol & Compazine to combat migraine & experienced severe agitation. The dr recognized phenothiazine-induced akathisia & countered it with Benadryl & Ativan. Years later I was, again, treated for HA. I double-checked the dr knew I couldn't take Compazine. He ordered chlorpromazine & Valium. Unfamiliar with the generic, I didn't realize it was Thorazine (in the same class as Compazine). Another bad reaction. I pulled the IV out, fled & paced at home for 15 hours. Surely, the dr knew I'd react negatively. A couple years later back to ER for the 1st time since the Thorazine. I explained my reactions in detail. This time I was given Reglan. Again, I ripped out the IV & was headed for the door when the nurse caught me. Repeated doses of an antidote worked. I learned, subsequently, it's common to react badly to Reglan if you reacted to Compazine. Either the dr was poorly informed or simply willing to risk my well-being. I've suffered at home in silence with ever since."

• Damom
• January 2, 2019

For Nausea/Vomiting "Went to the ER for a severe migraine...they gave me compazine and benadryl. 20 min later I was in a severe panic...ripping my IV's out. Calling out to the nurse saying I was leaving!! They had to give me more benadryl to reverse it. I left the hospital feeling worse than I did when I went in!! Horrible experience!"

• Renae...
• October 30, 2015

For Nausea/Vomiting "Had nausea from chemo and radiation and was given Zofran. Zofran did nothing to curb the nausea. I was just recently changed over to Compazine and the nausea is gone! I've not experienced any side effects whatsoever."

• Silve...
• Taken for less than 1 month
• December 15, 2017

For Nausea/Vomiting "I was born with chronic pancreatitis and chronic migraines so vomiting is a for sure thing every time I visit the ER. I have never in my life been traumatized by a medication until this encounter. It is like we are their lab rats, you feel helpless, insane, delusional, 51-50, a psychopath. You literally feel trapped inside your body if that makes any sense. I try to hold my composure off this medication because it literally makes you crazy. It should be illegal for them to give inject you with it without a warning on the side effects. You feel so weird for 3 days, it’s as if your innocence has been robbed from you, a form of violation."

• Shay
• November 6, 2019

For Nausea/Vomiting "This was, like many others on here have said, a terrifying ER experience. I was given Compazine for what they thought was a migraine, plus benadryl because they warned me about the anxiety. Upon giving it to me via IV, I felt a wave of panic enter my body. My heart stopped for a moment. I immediately wanted to get out of the hospital and tried to rip my IV out. I thought that would be the end of it. But it wasn't. I had crippling anxiety over the next 5 days! Yes, FIVE days. I had constant panic attacks where I would have to stop driving and pull over. One time I almost fainted during a meeting and had to go to the clinic. This drug made me dizzy, lightheaded, feeling like I was going to pass out all the time, gave me the strangest head pressure/tingling feeling, heart-racing constantly. I will never ever take this drug again. Worst experience."

• Asscher
• Taken for less than 1 month
• December 28, 2014

For Nausea/Vomiting "I was in the hospital suffering from post lumbar puncture headache and nausea/severe vomiting. IV Zofran did nothing, IV Reglan did nothing, only the IV Compazine gave me relief. Granted as soon as it ran out I started up again, but at least it allowed me a few hours of peace to sleep."

• Katie...
• Taken for 1 to 2 years
• November 8, 2022

For Psychosis "First and LAST time I ever received IV compazine, within minutes of hitting my veins I was severely anxious, like and acute psychosis. I jumped up from the bed, and said "I gotta get out of here, I gotta go". My husband was like "what the hell did they just put in your IV". He called the RN in, and he gave me IV benadryl which did not help me. For the next 3 DAYS, I was out of my mind, could not function, and honestly was scared to be alone for fear I may have hurt myself! My husband stayed home to care for me and make sure I did not hurt myself or take off running. Oral benadryl and oral ativan--NOTHING took the feeling away. Absolutely awful!! I have never in my life had feeling of hurting myself, or dealt with any mental health issues, it was COMPLETELY terrifying!! I don't understand why this medication is still on the market honestly!!"

• Bear
• Taken for less than 1 month
• June 27, 2019

For Nausea/Vomiting "I wish I could give this drug 0/10 stars. This is not a drug that I would give to my worst enemy--And I have tried MANY drugs for migraines! I was given this with the migraine cocktail in the ER, which also includes benadryl & toradol. I experienced extreme anxiety and restlessness. I wanted to rip the IV out of my arm and run out of the hospital... not that I could have done this anyways because it caused me to have extrapyramidal and dystonic side effects!!!!! When I got discharged from the ER, this was the worst night of my life. My friend had to sleep over because I was freaking out. The side effects lasted for 2 days."

• Miss
• Taken for less than 1 month
• May 30, 2018

For Nausea/Vomiting "I cannot believe all of these totally horrible experiences with compazine. I was given in my IV for severe nausea and I had absolutely no side effects what so ever. I have taken another one now that I am home before I went to bed, again no problems or side effects at all. Hard to believe so many people are having such severe reactions?"

• Patty
• Taken for less than 1 month
• May 16, 2019

For Nausea/Vomiting "It is absolutely horrible I went into the ER yesterday with a bad headache on one side they wanted to give me some cocktail with included compazine and Benadryl combined I said no, I should have done my research on compazine prior to getting it intravenously the worst mistake of my life I had shakes anxiety which I don't have the worst dry mouth of my life that I almost choked on my sugar pill I felt like it had been out in the desert for a year I could not keep my mouth moist fast enough. It has been almost 24 hours and I'm still not back to 100 percent yet. That drug is toxic I would never I don't care how much pain I'm in ever take that drug."

• dharr...
• Taken for less than 1 month
• March 4, 2017

For Nausea/Vomiting "I was given compazine through the IV for nausea and vomiting while admitted. It was an absolute nightmare that still makes me feel pure fear when I think about it. I thought I was going to die. At first, my legs just felt restless which I thought I was just having some anxiety, but then it really hit. I couldn't get my body to cool down, I started vomiting, then lost control of my bowels in front of the nurses. This lasted over six hours until they finally gave me something that knocked me out until it was over. I thought I was going to die. It scared both my partner who was there and myself to the point that I am now scared to take anymore medications fearing a similar reaction. They should really warn people about this drug."

• Sidly
• Taken for less than 1 month
• September 7, 2017

For Psychosis "After having had to take steroids for severe asthma all of my life I have been dealing with a very horrible side effects of psychosis on steroids. Unfortunately there are many people in the medical field he still do not know how to deal with that. I have learned to ask for Compazine and have been able to take small amounts to get back to a straight playing with my mental health and survive the hospitalization and the several weeks afterwards when I'm having to cut down the prednisones back to nothing. It has saved my life and has probably saved a few hospitalizations because a lot of people don't know how to deal with someone who says high doses of Cortizone make me psychotic. My long-term doctors know it but short term hospitalization Compazine saves me from all sorts of other issues that could come up that I've already dealt with in the last 64 years."

• Mahbu...
• Taken for 10 years or more
• February 3, 2017

For Nausea/Vomiting "I was talking to my sister about my bad reaction to a medication I took 15 years ago called Compazine. I took this prescribed medicine while at home. I remember my experience like it was yesterday. At first I felt a twitching in my jaws. All at once, my bottom jaw started going to the right, and my top jaw started going to the left. I could not stop it and I could not talk. In fact, my jaw felt like it was trying to break off my face. I remember the emotional and physical pain. Me and my husband were both crying, because we both didn't understand what was happening! My husband ended up taking me to another clinic, and they admitted me at once. So BEWARE! Just from talking - I found out this same medication hurt my sister just last year."

• Hannah
• May 19, 2016

For Nausea/Vomiting "I took this for my extreme amount of nausea causing anxiety. It did wonders for my nausea! It was wonderful and like a miracle. Until the 3rd time I took it... I had the worst experience of my life. My jaw got locked and stuck to one side, my eyes got locked looking upwards and I couldn't move them, my jaw felt as if it was trying to break itself and was so painful . I ended up sticking my finger down my throat to make myself vomit up the drug. It continued to lock my jaw up off and on for the next 48 hours. Never again. Be careful of the side effects. Worked wonders for my nausea and vomiting, but I would rather be throwing up than experiences those side effects"