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Compazine for Nausea/Vomiting User Reviews (Page 4)

Compazine has an average rating of 2.4 out of 10 from a total of 193 reviews for the treatment of Nausea/Vomiting. 14% of reviewers reported a positive experience, while 82% reported a negative experience.

Reviews for Compazine

  • Pooh
  • Taken for less than 1 month
  • March 23, 2019

"I went to the ER last night with nausea and vomiting. I was given zofran, but it had soon worn off. I told the doctor and he said he would give me something else. The nurse came in with the compazine. She gave it to me through my IV. Within minutes I started to feel really jittery and restless! I started to become anxious and fidgety, and I wanted to rip my IV out of my arm. The medicine worked for the nausea, but it's definitely not worth the side effects! It was the worst feeling ever!!! It has been 21 hours since and I still don't feel right. The symptoms have calmed down a lot but I'm still not 100%."

2 / 10
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  • Expec...
  • Taken for less than 1 month
  • October 20, 2019

"Worse experience ever. I had been experiencing morning sickness and vomiting while pregnant and had gone to the ER . I had been given compazine through an IV along with some fluids. Within a short amount of time I felt awful, a tremendous amount of anxiety came over me where I could not relax or even think to the point of functioning. Felt like jumping out of my body. There must be some legal consequences and responsibility behind this medication and what it has caused. No one should have to go through this nor do I think it’s safe for anyone, especially while pregnant ."

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  • Meano
  • Taken for less than 1 month
  • July 27, 2018

"I went to the hospital due to a severe migraine and nausea. I was given compazine via I.V. Oh dear! I immediately began having chattering teeth, severe anxiety, and uncontrollable clenching of teeth. I also could not remain still, as if I wanted to get out of there as fast as I could. I called the nurse in and the response was oh, yeah you feel kinda outta of it? Well yes it will pass don't worry" ARE YOU SERIOUS RIGHT NOW! It's just by the grace of God that I got home safely. My teeth continued to chatter, and could not sit still! I had to go back to the ER to get medicine to counter the side effects. I feel a little better now. Day 2 and still feel out of it. I WILL NEVER TAKE compazine again!"

1 / 10
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  • Abbyh...
  • November 15, 2017

"Was given compazine for the first time in the ER. It was mixed in a cocktail for my headache. After 3 minutes I started feeling uneasy and I started to have a full in panic attack, I’ve never felt that in my life! I ripped my IV out of my arm and started kicking the walls and stomping , they thought I was insane! I told them it was the medicine , they didn’t do anything just released me and I felt like my skin was crawling for 3 days. Was the absolute worst experience of my whole life !"

1 / 10
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  • Angel
  • Taken for less than 1 month
  • May 17, 2018

"I have been given Compazine in my IV and it was one of the most horrible experiences in my life! It almost immediately made me very anxious, I wanted to pull my IV out and just get out of the hospital! I felt zombie like and my face went numb. I the side effects like these for about 3 days! Never again will I take compazine!"

1 / 10
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  • Yvaine
  • June 24, 2019

"Worst medication! About 9 years ago when I was in high school I caught mono and was vomiting a few times when my mother took me to an ER/urgent care. They gave me an IV with compazine and a prescription for home. It wasn't until maybe the second day I couldn't move my muscles. I had ZERO movement to my body and could barely walk. Or get dressed. Nothing. I constantly shook like I was have a seizure. I couldn't sleep for an entire week! Let alone sit still. It was constant anxiety. It's like I lost all ability to relax. It was a living hell. When I went back to the urgent care the lady literally told me it was mono. I went home and continued to take this medication not knowing I had a severe allergic reaction. Finally went back again and got a doctor who actually knew what was going on! He told me to stop taking compazine ASAP. People get PERMANENT damage from this! It took over a month for this to leave my system and until this day the anxiety is still there."

1 / 10
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  • Anonymous
  • Taken for less than 1 month
  • November 30, 2017

"I went to the ER with nausea, they gave me compazine immediately I felt hot and restless . I freaked out they moved me from the hallway to a room where I became restless and angry . My jaw locked up and I was shaking uncontrollably, my heart raced and I felt like I was gonna die. My symptoms lessened after about 8hrs where I slept off and on. I went to a different ER and they gave me a small dose of Ativan but it didn’t make me feel any better. The next day I still feel panicky and my heart feels weird and the shaking comes and goes also have horrible diarrhea. Worst experience of my life."

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  • Kader...
  • Taken for less than 1 month
  • April 2, 2019

"I've had three OHS (open heart surgery) so I've had my fair share of IV medicine. NOTHING, and I repeat, absolutely nothing I have taken has made me feel as awful as this did. Five minutes after receiving the dose of compazine I started getting restless, like I wanted to crawl out of my skin. I complained about how uncomfortable I truly was, and the doctor just said oh yeah, that happens. Please don't take this, it may have helped my pain. But here I am 19 hours later still feeling like complete garbage. I honestly wish I would have read these reviews first."

1 / 10
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  • 1aurafu
  • September 29, 2017

"I took this during my first trimester of pregnancy for nausea. It worked wonders for about two days. On the third day I started to feel strange at work and took a break. My forehead and throat felt like they were tightening. I decided to go home and about halfway there I felt my jaw forcing itself to the left while my top teeth forcing to the right. I couldn’t control my face or tongue whatsoever. I should have went to the emergency room but instead I decided to call it a day and try to fall asleep. I didn’t fall asleep until 2am or so when the flexes in my face finally subsided. Strangest experience of my life. My neck and jaw were so sore for days afterwards."

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  • Horri...
  • Taken for less than 1 month
  • September 18, 2016

"The absolute worst experience with an antiemetic I have ever had. I literally panicked in the hospital to the point I almost pulled my iv out. Zofran stopped working for my hyperemesis gravidum...but I would rather live with nausea vomiting day in and out then feel the uncontrolled anxiety and restlessness I felt with compazine!"

1 / 10
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  • LCano
  • Taken for 6 months to 1 year
  • August 20, 2020

"I was first given Compazine orally for anxiety and nausea. It did not appear to have any side effects. A year later I was hospitalized following surgery and extremely nauseous so after giving me Zofran to no avail, they gave me Compazine IV. It burned going into my arm. I became very agitated and restless, my body could not stop shaking and I felt like I was going to jump out of my skin. Luckily, they gave me Benadryl and that helped calm me down a bit but it took a couple of days to feel myself again. Will never take IV again."

4 / 10
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  • This...
  • Taken for less than 1 month
  • November 17, 2019

"I went to the ER for stomach issues as a teen and I took it went home and 45 minutes later my jaw shift all the way to the left and I couldn’t control it and my neck started leaning to the right I was rushed to the hospital and given Benadryl through an I’ve lucky it worked I was in so much pain"

1 / 10
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  • Katha...
  • June 23, 2020

"took this for a migraine cycle and while it helped with the migraine. When the nurse gave it to me it made my heart race and it made me have the worst panic attack, I couldn’t stay still because my legs were restless and I was extremely hot and loopy I won’t take this again."

2 / 10
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  • Ahri
  • Taken for less than 1 month
  • October 31, 2016

"I had been suffering from severe nausea and vomiting on and off including migraine, fever and flank pain. It was my second time in the ER so they gave me compazine and I'd never had it, it relieved my nausea and migraine but I started feeling so restless I was freaking out, like I wanted to rip out my iv and leave and run away. Then they told me it's a side effect and I already suffered from severe anxiety it made it 1000x worse. I had the worst time trying to sleep, then had the weirdest dreams of my life. They gave me Morphine shortly after which calmed me a little and took the rest of my pain away but I was hoping it'd honestly put me out. 24hrs layer and I still feel that restlessness in my body but it's so much better than it was."

1 / 10
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  • Drambo
  • Taken for less than 1 month
  • November 5, 2022

"Was given this drug in the ER for a migraine and nausea, they didn’t tell me what they were given and I had the worst headache and didn’t even ask. Low and behold this medicine ruined my life after one dose!!! Was given with bendrayl and I felt extremely anxious panicky my legs and body were so restless I thought I was gonna die on the CT table I couldn’t put words together. It’s been 5 days and I’m still not the same panic attacks galore anxiety tight band around head/headache fear of doom and dizziness galore. This should be illegal"

1 / 10
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  • Super...
  • August 22, 2019

"I feel for all of you very much. All of those bad experiences, I also had. Plus doctors and nurses don't seem to care at least most don't. About 13 years ago I went to the ER for nausea, vomiting and diarrhea. I didn't feel well when I went in. As soon as they Compazine in my IV, I felt terrible panic, restlessness, anxiety. I could not sit, lay down stay in one place for more than 5 minutes. I pulled my IV out and started running to my friend. I thought maybe I had a stoke. I didn't know. My friend tried to talk to the doctors. I was out side I couldn't do anything to feel any better. I waited to die. I was afraid I would hurt someone. I was 1 of the top weightlifters in the world. I started bang my head as hard as I could on the concrete wall. Then I went back in the hospital bleeding. I thought then the doctors would do something to help me. They called the police, my friend got me home. I was worse. I took some Xanax. I still have anxiety from that experience."

1 / 10
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  • Kswear
  • Taken for less than 1 month
  • July 21, 2019

"I was given this awful medication in a migraine cocktail. Within minutes I was so anxious that I yanked my IV out and ran out of the hospital room. For hours I couldn't stop moving my legs. Its been 3 days and I'm still so anxious. I made the pharmacy write in notes that I was allergic to compazine - prochlorperazine so this never happens again."

1 / 10
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  • Hope
  • January 31, 2020

"Was given this at the E.R about 4 months ago for gallbladder related nausea, had the worst panic attack I have ever experienced, tried to rip the I.V out of my arm and run out of the hospital, have had many extreme panic attacks since. I have had panic attacks before but never within 6 months of each other. I get them at least 10 times a month now. Wish I had never taken this medication."

1 / 10
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  • momlo...
  • Taken for less than 1 month
  • October 31, 2022

"It has been a little over six months since I was given compazine through my IV, when I had a migraine and I am still not right. It’s important to note that prior to the injection I have never had any problems with mental health besides intermittent anxiety (mild). I went to the ER for a severe migraine that had been lasting a few days. I was given compazine through my IV for the pain. I immediately had the worst panic attack of my life. I can’t even compare it to other panic attacks I’ve had because it was profoundly horrific. Wanting to escape, suicidal thoughts, terror, wanting to rip the IV out of my arm, and extreme restlessness. I have had debilitating anxiety ever since. After readings many of the reviews, I see most people feel better after a few days, but that hasn’t been the case for me. Have now been struggling with never feeling at peace or comfort. I can no longer feel love, happiness, joy or even experience laughter. I walked out of that hospital a different person. Please avoid."

1 / 10
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  • FF89
  • Taken for 1 to 6 months
  • April 12, 2024

"This medication has been very helpful for me with extreme nausea and vomiting. It was recommended that I take Benadryl with it for side effects, so I take one with one. It relieves my symptoms within 30 minutes; it's been a lifesaver. I didn’t have any adverse reactions like others, except fatigue, but that's to be expected, especially with the Benadryl."

8 / 10
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  • MissA...
  • Taken for 6 months to 1 year
  • February 18, 2019

"I was given compazine for nausea and vomiting when I was having monthly (girls) problems which almost always included throwing up with pain. Violent spasms like tetney lockjaw I did thousands of dollars of damage to my teeth, and my whole jaw was crooked for days after. But Drs all told me it was "stress" all in my head not the meds. One time when I was in the hospital and they gave me compazine by injection it started within a few minutes, yup it was the compazine. Also have to be careful with other meds that may contain it. I had Tigan which worked pretty good but now no longer made. Last time Dr gave me Zofran but had a tough time getting the insurance to approve it as they wanted to give me the cheaper compazine generics. Be very very careful as I have had a few pharmacists tell me some other meds were not related only to find out that they were. Be sure to do your homework and double triple check what is in what."

1 / 10
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  • Liv
  • Taken for less than 1 month
  • March 21, 2019

"I went to the ER when I was experiencing headaches and vomiting due to a new medication I was put on. The doctors gave me compazine, toradol and Benadryl through my IV. After a few minutes I experienced the worst feelings of my life. I was thrown into a huge panic attack, I couldn't sit still, my heart rate rose to over 130. I had to stay in the hospital for 5 extra hours just to get my heart rate to return to normal. It took 24+ hours for the initial panic feeling to go away and now going on 48 hours my head still feels all foggy and I get dizzy when I stand up for long periods of time. I hope I return to normal soon and I would not recommend this medication to anyone!!"

1 / 10
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  • Dee
  • Taken for less than 1 month
  • March 22, 2019

"26 years ago I was prescribed this for vomiting and soon after I took it at home I had a stroke (at 22 years old) You can imagine the trauma I went through. I was home alone with my infant when it happened. I lost all control of the right side of my body. I could barely speak. I got to a phone in the house (no cellphone back then 26 years ago) and called my sister who lived closest to me. She couldn’t make out what I was saying until I started crying, then she realized I was in danger So she rushed over and got me to the nearby hospital. By the that time I was also beginning to swallow my tongue. I thought I was gonna die. I apparently passed out and when I came to I was hooked up to things, I was feeling much better from whatever they did for me, and had told me I had a stroke. Because of how young I was there wasn’t too much permanent damage. My right side of my face is still slightly lower or droopy than the other side from the incident but my brain is ok. Scary!"

1 / 10
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  • Bee
  • Taken for less than 1 month
  • September 19, 2019

"If you are ever offered a sedative / nausea medication please be aware that every single one of these recollections and experiences are true. I could compare almost exactly to each and every one of these stories. DO NOT TAKE COMPAZINE. It has been three days and I still do not feel normal."

1 / 10
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  • Anonymous
  • July 28, 2009

"I am an older adult in good health. I originally had dizziness (possibly from a virus or sinus bug) which caused nausea. This medication took away both symptoms within 1-2 hours and I was able to carry on with my normal activities."

10 / 10
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19 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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