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Compazine for Nausea/Vomiting User Reviews (Page 2)

Compazine has an average rating of 2.4 out of 10 from a total of 193 reviews for the treatment of Nausea/Vomiting. 14% of reviewers reported a positive experience, while 82% reported a negative experience.

Reviews for Compazine

  • Klauren
  • Taken for less than 1 month
  • May 28, 2019

"Went to ER for a migraine I could not control. Was given compazine by IV. Instantly felt like I was crawling out of my skin couldn't sit still. Went home and a few hours later ended back at the ER due to uncontrollable body movements. When I got there the doctor told me it was dystonia, which is a side effect reaction from the medication compazine which is unrerversible. It has been almost 7 months since this day and I still have uncontrollable muscle movements and severe anxiety. Please do not take this drug my life has been hell ever since."

1 / 10
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  • Anonymous
  • Taken for less than 1 month
  • April 9, 2015

"Very bad side effects. Given by IV in the emergency room for severe migraine. Jaw clenching, agitation, loss of appetite, groggy, incessent urination (with a fowl smell). Side effects lasted for a week after administration."

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  • Kleins
  • October 19, 2015

"I was prescribed compazine in 1989 for severe morning sickness during the forth month of my second pregnancy. By the third day, I was rushed to the hospital because my chin locked over my left shoulder, my tongue hung out of my mouth impeding my speech, the muscles in my eyes froze, keeping me from blinking. My five year old got home from school and found me drooling on my self, grunting b/c I could not speak. Good thing I'd taught her how to call 911. Shortly, an ambulance drove up and rushed me to the emergency room. They thought I'd had a stroke. Luckily, I had the vile of compazine in my purse. Needless to say, my son was born with neurological issues which have lasted a lifetime."

1 / 10
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  • Hano
  • Taken for less than 1 month
  • September 9, 2019

"I went to ER for uncontrollable vomiting, I was given compazine (don’t know the dose but was via IV push and a syringe full). Immediately, I felt anxious and panicky. When I asked the nurse If this was suppose to happen she said If anything should make me feel more relaxed, WRONG! It’s been exactly six days and I still feel overly anxious, strangest and most scary vivid dreams and can not sit still. Have to walk nearly 8 miles a day to barely be able to sleep at night. BELIEVE THE REVIEWS, I HOPE AND PRAY SOMEONE CAN SEE THESE AND PREVENT THE AWFUL SIDE EFFECTS OTHERS ARE EXPERIENCING! That is definitely going to be listed as an allergy to medication in future. I would had much rather dealt with throwing up from food poisoning than deal with these endless awful feelings. If anyone knows when will I be feeling normal again and constant panic and anxiety will go, and the as awful scary dreams would stop please PLEASE let me know or post here, I will check regularly"

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  • Nause...
  • August 18, 2014

"Read the side effects carefully. I had a severe distonic reaction and had to spend the day in the emergency room after just 1 pill. I have been advised by my doctor to never even take anything in this family of medicines."

1 / 10
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  • Neila
  • September 14, 2019

"Absolute worst experience. Please read the reviews. They gave me this for a headache, heart rate went to 155, I felt like I was going to die, never in my life have I felt that level of panic, my first instinct was to rip my IV out. Became restless, skin crawling feeling like I needed to jump out of my body. It was the most uncomfortable I have ever felt. Once home I paced back and forth for hours, I could not sit or lay down. I felt like I was losing my mind - I felt just wanted it to stop. I called the hospital, they suggested benadryl, the ONLY thing that let me lay down after hours. I took a couple more the next day to be able to stop moving every second. It's been 33 hours since I was given this med and I am still restless, cannot stop moving my legs. I don't care how much pain or how nauseous I could be or how much someone paid me, never in my life would I take this again and I wish I looked it up first."

1 / 10
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  • Marky...
  • Taken for 5 to 10 years
  • July 12, 2014

"Been taking for years for nausea from Irritable Bowel Syndrome etc. Works great and quickly! Get restless legs next day but that ends quickly. Heard that if taking it regularly long term you should have liver and kidneys monitored as it can do damage to them!"

10 / 10
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  • Taano
  • March 2, 2019

"Went to ER and was given this drug w out any details, not one time did the nurses tell me what was about to happen. I thought I was going crazy!!! I could not sit still, it was the worse experience ever!!!! Do NOT allow the medical sheep give this to you. Matter of fact when you go to ER take someone with you and ask questions and don’t let them put anything in your IV with out Googling it!!!!! This is next day and still not 100 %."

1 / 10
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  • Anonymous
  • Taken for less than 1 month
  • November 5, 2019

"I agree with the review about how all these other reviews have identical symptoms. I to question if they are for real. I had a migraine and severe nausea and a simple 5 mg over an hour’s time worked for me."

10 / 10
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  • Manda...
  • Taken for less than 1 month
  • September 3, 2019

"This was the most awful medicine I have ever had I thought I was going to die my heart rate when up to 180 I couldn't be still. I tried ripping my IV out and when I told the nurse she laughed and said just calm down your fine. It was horrible. It been 3 days and I'm still have panic attacks muscle twitches all the time this medicine has ruined my life please do not take this"

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  • Anonn...
  • January 31, 2017

"This is the only medication I have ever been given in my ENTIRE life that has made me literally want to rip out my IV and run out of the ER. I was given this in the ER to curb the side effects of my lumbar puncture. I have anxiety and RLS so in the beginning I thought I was just experiencing a minor panic attack. I felt so restless that I had to go to the bathroom just to do something with myself. When I got back to the bed I immediately told my gf that I wanted to leave. Was pushing the call light. And damn near left screaming. I flipped my shot on the doctor and he said this was a common side effect. I told him I feel like I'm going to have a panic attack and he gave me Benadryl and some kind of benzo. Absolutely horrid."

1 / 10
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  • Anonymous
  • March 7, 2010

"I experienced the "restlesss, anxious" side effects from this medication and it's been almost 24 hours and I am still feeling it in my legs. My headache is gone which is great, but my legs can't stop moving."

4 / 10
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36 Report
  • mmmmm...
  • July 11, 2016

"If i could rate this lower than a 1 I would. Worst. Experience. Of my life. I had severe nausea from a dental infection in the hospital and the doctors gave me compazine through IV. I don't even know when this happened but I had a crazy out of body experience. I saw myself laying in my bed and had NO idea where I was. I thought I was in Arizona at first at a hotel and then freaked out because I had no clue who the people in the room were (my parents, my regular nurses). The room spun and then I vomited everywhere. It was horrifying. I was nauseous for about twelve more hours and then had hallucinations. I saw people walking in and out of my hospital room that I knew damn well weren't real or there.DO NOT TAKE THIS DRUG."

1 / 10
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  • EAano
  • Taken for less than 1 month
  • August 16, 2019

"I've never experienced anxiety, I don't take any medication for anxiety, but thanks to this drug I had my first panic attack. I went to the ER for extreme nausea due to pain killers given to me to alleviate the pain of some kidney stones. Right after being given this medication I started feeling jittery and like I couldn't breathe. 10 minutes later I wanted to rip out my own IV, my entire body was shaking and was having facial contractions. The doctor laughed it off saying I was being overly dramatic and I just needed to breath. It was the worse experience I've ever had, and I thought the kidney stones were bad enough. 3 days later and I'm finally starting to feel like myself again. I will never take this drug again and have no idea why it's still in the market."

1 / 10
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  • Meeee...
  • March 30, 2014

"I have been dealing with chronic nausea/vomiting for almost a year. I have had every test in the book and they all come back negative. I've tried medications for irritable bowel syndrome and I've tried Phenegran and Zofran. None of which worked. I also used the transdermal Scoplamine patch, which helped a little. Finally, my doctor prescribed Compazine suppository and I have had great relief of my nausea/vomiting. I hope to be able to stay on this for a long time. It is a wonder medicine."

8 / 10
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  • Silly...
  • November 22, 2019

"After having a migraine and horrible muscle pains for 20+ hours I went to the ER. This medication compazine was in the Migraine "Cocktail" they gave me. I have never felt the way it made me feel. I couldn’t sit still, my body didn’t feel like my own. I was literally freaking out. I wanted to get out of there, I was ready to rip out my IV and run. My husband tried to help keep me calm. When the second nurse came in she said this happens sometimes, and that they should have given it at a slower rate. I do not know if that would’ve made a difference, and I am not giving it a second try. Worst medical experience I’ve experienced. I do not blame the DR. ir Nurses, but this medication has left me traumatized."

1 / 10
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  • Anonymous
  • August 15, 2018

"I was given this for nausea & a migraine. It did not help me with either, but made me anxious and I felt like my skin was crawling. I've never experienced anything like that. I was ready to pull the IV out myself & escape from the room if they didn't hurry up and discharge me. I've never had a response to a medicine like that before, and it was absolutely awful. Worst hour if my life."

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  • Rori
  • Taken for less than 1 month
  • January 29, 2021

"When I had the stomach flu I was given compazine as a suppository so that I could eat again without vomiting. It seemed to work okay at first, but I would soon find myself fighting for my life. It started with pain and difficulty speaking, but quickly morphed in to my body contorting backward involuntarily to the point where I couldn't move any of my torso, legs, arms, etc on my own. In quick progression, I went from barely able to voice a whisper to unable to breathe at all. I was suffocating and if not for swift action of EMTs and a life-saving dose of benadryl, compazine would have succeeded in being fatal. After the fact, I heard a doctor refer to my adverse reaction as "compazine lockdown". I'm lucky to have lived through my experience taking compazine."

1 / 10
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  • Kon
  • Taken for less than 1 month
  • November 15, 2019

"I went to the ER yesterday for a migraine and was given compazine and fell asleep, however when I woke up I felt off like something wasn't right. I couldn't stay still, I just felt uneasy. It wasn't until I just read the comments in this thread that I realized that I the compazine had a side effect on me. I will definitely put it on my non-medication list. I still feel weird the next day. I even called off of work. I hope this helps someone else."

5 / 10
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  • Me25
  • January 22, 2021

"I went to the doctor because of my dizziness and nausea, the doctor had prescribed Compazine to me for my nausea which didn’t even work. Jump forward a few days and I go to the ER to see if they can do something about it when I noticed I started having seizure like attacks where my body will stay in one position and my eyes would roll to the back of my head and the doctor said it was because I was allergic to the drug even though I didn’t know, but isn’t Compazine supposed to no longer supposed to be sold"

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  • MadPi...
  • February 10, 2018

"I went to the ER with a migraine and I got this through an IV. I was totally fine and all happy until this drug hit me. I went completely insane. I got claustrophobic, I wanted to kill myself, I started twitching, and I got super anxious. They gave me some Benadryl which helped so they sent me home. On the way home it happened again, and it kept happening all night even after I kept taking Benadryl. The only time I felt not insane was when I was sleeping but I was still having weird dreams. The next morning I woke up and I was still really anxious but the serious side effects went away. For 2 more days I still felt anxious and it was the worst thing ever. Everyone told me this was really rare and I don't think any of the people there at the ER really knew what was going on. This is a scary drug. I just wanted to share my story."

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  • NE603
  • Taken for less than 1 month
  • February 1, 2019

"I had experience high agitation and restlessness with this drug before so it’s been in my allergy list, unfortunately I was going through a difficult procedure and it’s the only anti-emetic this office offered. It had been over 10 years since I took it so I figured I’d try it again. Bad idea. This drug causes severe anxiety, agitation, muscle pain and a general feeling of needing to rip out of your skin!! I remember now why it was on my DO NOT USE list, the affects stay with you for a long time too. I will never take this again.. there’s a reason it’s listed as a mental health drug/antipsychotic.. IMO it MAKES you psychotic."

2 / 10
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  • saaaa...
  • February 21, 2016

"Went to the ER twice with a severe migraine, both times given Compazine. It definitely helps with relieving the pain but the side effects out weigh it for me. Felt like my skin was crawling, restlessness, skin rash, dry mouth, anxiety (triggered a panic attack both times), brought up a lot of bad thoughts of how I was dying. Long term, rebound headache, insomnia, loss of appetite. Also had it with Benadryl once and that scared me."

1 / 10
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  • Birdie
  • Taken for less than 1 month
  • August 23, 2020

"Went to the ER with extreme dizziness. They wound up giving me Compazine. I wasn’t even familiar with what it was. I felt strange at first, but then my hands contorted & froze. My mouth had almost completely clamped shut. An orderly or a CNA just happened to come by to empty trash. I barely was able to say please go get someone something’s not right. The dr at first thought I had stroked. He ran some test gave me some Benadryl which helped. I would never take this drug again."

1 / 10
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  • anony...
  • November 29, 2018

"My mother had a colonoscopy and had a vocal chord spasm which caused her to cough during it. They gave her some medicine (don't remember the name) to help dry up her secretions and calm down the coughing. This made her chest tight, painful, and made her feel nauseous after she got home. I took her to the ER, she is allergic to Reglan, so they gave her a mix of benadryl and compazine for nausea. Within 5 minutes she was jittering around and felt like she wanted to rip her IVs out and run home. Her anxiety skyrocketed and her heart rate went up to 154 bpms. It wasn't until they gave her Ativan that her heart rate went down and she was able to calm down. We got sent home & she was still anxious and fidgeting around for about 4 hours until she finally fell asleep. She woke up and still felt a little anxious & fidgety but not near as bad as last night. One of the worst experiences she & I have ever had and she is going to have it put as she is allergic so she never has to be through it again."

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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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