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Primidone and Irritability: What Users Say

Brand names: Mysoline

Irritability: mentioned by 3 users (2.8%)

Based on user experiences from 109 Primidone reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

dizziness 14.7%
tremors 11.0%
drowsiness 7.3%
nausea 7.3%
tiredness 7.3%
disorientation 4.6%
brain fog 3.7%
depression 3.7%
fatigue 3.7%
irritability 2.8%

Reviews for Primidone

Showing 3 reviews tagged with "irritability". Clear filters to view all 109 reviews.
Commonly mentioned side effects
  • Anonymous
  • August 27, 2012

For Benign Essential Tremor "I was diagnosed with Benign Essential Tremor a month ago. My doctor started me out on 12.5 mg of Primidone. I have increased my dosage every 3 to 4 days by 12.5 mg. I'm at 112.5 mg and the tremors are still there. I also take a beta-blocker as well. The side effects are flu-like for me the day after I up my dosage. Then I have a 'good day' and then the tremors start all over again. I cannot climax, as a horrible side effect, so I'm frustrated in more ways than one."

3 / 10
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104 Report
  • A N...
  • December 23, 2010

Mysoline (primidone) for Seizures "I was prescribed this medicine back in the late '80s for seizure control. I recently stopped using this in 2010. It controlled my seizures well, but I did not realize the side effects of it. Side effects were irritability, anger, increased depression, and behavior. Because I literally grew up with this medicine, I can now see these issues after changing the medicine. My brain was built to use it during puberty/young adult. This does control seizures and actually suppressed anxiety by slowing down all brain functions. Be aware that epilepsy is comorbid with depression quite often and this medicine may enhance/increase depression symptoms."

7 / 10
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44 Report
  • Bon...
  • Taken for 1 to 6 months
  • June 12, 2019

For Benign Essential Tremor "50 mg BID dosage. My age 76. Had every listed side effect including EOM pain, panic attack, mania, suicidal thoughts and actions, muscle cramps, irritability, depression, diplopia, excitement. Took this for 7 months, did not realize side effects until 2 weeks ago. It should not be given to the elderly."

2 / 10
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19 Report

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