Primidone Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Primidone	Propranolol	Gabapentin	Enter another drug to compare

Primidone

Propranolol

Gabapentin

Prescription only

Prescribed for Benign Essential Tremor, Seizures, Epilepsy. Primidone may also be used for purposes not listed in this medication guide.

Prescription only

Propranolol is mainly used for blood pressure and angina control; however, it also has a role in migraine prevention and the treatment of essential tremor. Propranolol may cause vivid dreams and is... View more

Prescription only

Gabapentin is an anticonvulsant with pain-relieving effects that may be used to treat certain seizure disorders or relieve nerve pain. Common side effects include dizziness or drowsiness and it may... View more

More about Primidone

More about Propranolol

More about Gabapentin

Ratings & Reviews

Primidone has an average rating of 6.0 out of 10 from a total of 109 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 28% reported a negative effect.

Propranolol has an average rating of 8.2 out of 10 from a total of 1377 ratings on Drugs.com. 77% of reviewers reported a positive effect, while 12% reported a negative effect.

Gabapentin has an average rating of 7.1 out of 10 from a total of 2573 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 21% reported a negative effect.

View all 109 reviews

View all 1377 reviews

View all 2573 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Dizziness (14.7%)
Tremors (11.0%)
Drowsiness (7.3%)
Nausea (7.3%)
Tiredness (7.3%)
Disorientation (4.6%)
Brain fog (3.7%)

View all Primidone side effects

Tremors (10.5%)
Anxiety (6.8%)
Tiredness (6.6%)
Increased heart rate (6.5%)
Dizziness (5.2%)
Sweating (4.9%)
Headaches (4.1%)

View all Propranolol side effects

Dizziness (7.3%)
Drowsiness (7.0%)
Anxiety (5.7%)
Tiredness (3.9%)
Weight gain (3.8%)
Insomnia (3.7%)
Memory loss (3.4%)

View all Gabapentin side effects

Drug Class

Barbiturate anticonvulsants

Gamma-aminobutyric acid analogs

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	100 each
Strength	50 mg
Per unit^*	$0.25
Cost^*	$24.57

View all Primidone prices

Quantity	50 each
Strength	20 mg
Per unit^*	$0.35
Cost^*	$17.39

View all Propranolol prices

Quantity	100 each
Strength	300 mg
Per unit^*	$0.24 - $0.33
Cost^*	$23.69 - $33.10

View all Gabapentin prices

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Dosage Forms

Oral tablet

Intravenous solution
Oral capsule, extended release
Oral solution
Oral tablet

Oral capsule
Oral solution
Oral tablet
Oral tablet, extended release

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

12 hours

6.4 hours

6 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category N Not classified

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 677 drugs are known to interact with Primidone:

235 major drug interactions (691 brand and generic names)
415 moderate drug interactions (2749 brand and generic names)
27 minor drug interactions (100 brand and generic names)

A total of 589 drugs are known to interact with Propranolol:

47 major drug interactions (215 brand and generic names)
492 moderate drug interactions (3283 brand and generic names)
50 minor drug interactions (611 brand and generic names)

A total of 270 drugs are known to interact with Gabapentin:

28 major drug interactions (148 brand and generic names)
232 moderate drug interactions (1027 brand and generic names)
10 minor drug interactions (52 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Ask your doctor before using primidone together with alcohol, this can add to dizziness, drowsiness... View more

Food can enhance the levels of propranolol in your body. You shoud take propranolol at the same... View more

Alcohol can increase the nervous system side effects of gabapentin such as dizziness, drowsiness... View more

Disease Interactions

First Approval Date

March 08, 1954

November 13, 1967

December 30, 1993

WADA Class View classifications

N/A

P1 - Beta-Blockers

N/A

More Information

Patient Resources

Gabapentin uses

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Primidone Alternatives Compared

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