Skip to main content

Paliperidone for Schizophrenia User Reviews (Page 2)

Brand names: Invega, Invega Sustenna, Invega Trinza, Invega Hafyera

Paliperidone has an average rating of 4.2 out of 10 from a total of 282 reviews for the treatment of Schizophrenia. 28% of reviewers reported a positive experience, while 56% reported a negative experience.

Reviews for Paliperidone

  • Jiddo
  • Taken for 1 to 2 years
  • October 9, 2021

Invega Sustenna (paliperidone) "I was misdiagnosed due to an incident. Ever since I got this injection I’ve been feeling less of myself. I’ve gained weight at least 90 lbs, no emotion, barely sleep at night (5 hours), foggy mind, can’t think, bad concentration, less dopamine, shortness of breath, no creativity, and no personality. What’s the point of having a medicine that has worse side effects than the problem?"

1 / 10
Was this helpful?YesNo
36 Report
  • Deb
  • Taken for 1 to 6 months
  • July 25, 2020

Invega (paliperidone) "Taking Invega makes me spaced out and wierd. Spend most of my time lying in bed. Feel miserable. Wish I don’t have to take the medicine. But my sister is supervising to make sure I take the medicine. What should I do? Feel good when I am not taking any psychotic medicine"

1 / 10
Was this helpful?YesNo
46 Report
  • Anonymous
  • August 11, 2018

Invega (paliperidone) "This drug ruined me. I was fine before after they forced me to take it. I've been unable to write music since which was what I had a passion for. This drug has made me depressed and given me anxiety which I was never experiencing before the drug. Beware of this drug it helps some and can ruin others"

Was this helpful?YesNo
60 Report

Frequently asked questions

  • PROFIT...
  • March 11, 2016

Invega (paliperidone) "these drugs are dangerous... they ruined my life. made my illness much worse. the doctors are do not believe me as they think I'm an inferior life form. SYMPTOMS INCLUDE TOOTH DECAY LACK OF MOTIVATION EXTREME WEIGHT GAIN HEART PAINS REDUCED LEVEL OFCONSCIOUSNESS THEY ALSO MADE EXTREMELY DELUSIONAL TO THE POINT I DIDN'T EVEN BELIEVE ANYMORE."

1 / 10
Was this helpful?YesNo
75 Report
  • Yes
  • March 11, 2019

Invega Sustenna (paliperidone) "This medicine is horrible every time I take it I am unable to workout. I can't even run a mile I am so weak. I get restless leg syndrome, fatigue, weight gain, and blur vision. I'm done taking medicine sick of it"

1 / 10
Was this helpful?YesNo
50 Report

Are you taking this medicine?

  • Pooh
  • Taken for 1 to 6 months
  • May 3, 2020

Invega (paliperidone) "I was taking clozaril for about 24 years. My doctor stopped my medicine and didn’t taper down. Instant stop. He then overdosed me on 256 mg of the shot. I had young emotions. No thought left. Couldn’t remember how to turn the key in my car. My legs started going up and down, face twitches. Forgot how to cook. Just could sit there and not move. My head started shaking. I stopped this drug but my mind never came back. I’m slowly losing love and emotion for life. If you love somebody don’t ever let them take invega. It is the worst drug on the market"

2 / 10
Was this helpful?YesNo
41 Report
  • divya...
  • Taken for 1 to 6 months
  • November 2, 2019

Invega Sustenna (paliperidone) "Bad drug, it increases prolactin level's by a lot, in fact this drug ranks among the highest drugs that increase serum prolactin levels, and massive increase in prolactin levels reduces your testosterone by a hand full, don't expect to have a baby while on this medication. Don't expect an erection, Don't even bother with sex drive, that's for losers anyway. A massive decrease in libido. In short, this drug among a few other anti-psychotics will leave you feeling like a mix between a two year boy and a two year old girl."

1 / 10
Was this helpful?YesNo
44 Report

More FAQ

  • inveg...
  • August 7, 2016

Invega (paliperidone) "This medication completely ruined my life. I gained 15kg over six months on this injection whereas before I was fit. I grew manboobs on this medication. I have no libido and complete sexual dysfunction. This medication gives you terrible anhedonia. I was forced to take Invega Sustenna after some stupid psychiatrist diagnosed me with "psychosis". I had no symptoms of psychosis."

1 / 10
Was this helpful?YesNo
64 Report
  • Lew
  • December 22, 2019

Invega Sustenna (paliperidone) "I now have a deadly and nontreatable heart condition called a Left Anterior Fascicular Block (LAFB) due to over prescribed high doses of Invega and not being diagnosed 3 years in a row with hyperlipidemia (high cholesterol and extremely high triglycerides) and hyperprolactinemia (abnormal hormones causing loss of erection and sperm production) and 'reduced function' stage 2 kidney damage as well as 65lbs weight gain, none of which was diagnosed or referred to a PCP for treatment. Now I am without a treatment plan and my fate is sealed. Bad drug period."

1 / 10
Was this helpful?YesNo
41 Report
  • Onimoru
  • Taken for 5 to 10 years
  • April 20, 2020

Invega (paliperidone) "I have been trying for 7 years to get off the monthly Invega shot because the side effects make me feel like I’m in a nightmare. I’ve gained 80 pounds, trouble getting to sleep and staying asleep, no sex drive so no point to having a girlfriend, I feel down all the time, have wet stools, heartburn constantly, frequent headaches and I could go on. If you have a loved one on this drug ask them to be honest about the constant suicidal thoughts."

1 / 10
Was this helpful?YesNo
38 Report
  • Gains
  • Taken for 2 to 5 years
  • September 26, 2020

Invega Sustenna (paliperidone) "I personally don't like this medication at all. It is simply impossible to stay lean and fit while taking it. Does it manage your symptoms of bipolar/schizophrenia/schizoaffective disorder? Yes. But myself and I believe many other people get to a point where they want to move on with their life after years of mental clarity. This drug will prevent that and prevent you from living a healthy lifestyle. It's been proven to elevate blood lipids to unhealthy levels and in some cases cause heart dysrythmia. It's a good medication to stabilize patients with the mental illnesses listed above, but I truly believe this medication should not be prescribed long term, especially if the individual prescribed it has managed their symptoms for multiple years."

2 / 10
Was this helpful?YesNo
35 Report
  • Ferv
  • September 9, 2018

Invega Sustenna (paliperidone) "It works! but you have to want it too. Mental illness is an illness of the brain. The mind.. So you have to couple your taking of available meds and therapy. You have to change the way your mind works and thinks. Think on purpose for up to an hour a day by repeating a phrase or quote such as if you're a voice hearer repeat up to an hour a day (I cannot hear voices, they aren't real) x repeat. Fish oil, good sleep, eat healthy and exercise every other day. Look after yourself and work your thought life out. I have schizophrenia, Bi-Polar and depression and hold 2 small businesses that I run for most of my work-week (Music Studio owner operator and Stock Market Trader) I've had schizophrenia for 14 years and for 7 of those years ran a highly successful business where I used to live (talking 7 figures) EAT healthy! THINK right, Exercise AND Do what you know you should! positive positive positive. you CAN do this!"

9 / 10
Was this helpful?YesNo
47 Report
  • Leah
  • Taken for 5 to 10 years
  • June 12, 2018

Invega (paliperidone) "I have been taking Invega prolonged release tablets for 8 years. I was diagnosed with schizophrenia and put on 3mg and it took a little while for the delusions to end. I then fell into deep depression. I couldn't stand my head the way it was. This drug blocked all my mind wandering that I loved so much. I was given a 6 week course of ECT and put on 75mg dothepin antidepressant and invega upped to 6mg. When the dose was increased to 6mg I had heart palpitations and couldn't sit still in a chair from stiff joints and was constantly falling asleep. My psych blamed invega lowered my dose to 3mg and increased my dothepin to 150mg. I was still robotic in thought and movement but I could lead a productive life. My head did feel very dry and I was in survival mode though. I started having 2000mg fish oil capsules a day and my thoughts became fluid and so did my joints and movement. It's not a cure but I would recommend fish oil capsules to people with psychotic illness taking these meds."

8 / 10
Was this helpful?YesNo
47 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • December 14, 2018

Invega Sustenna (paliperidone) "I started taking this medication as a monthly injection for Hearing voices/ paranoia and I took it for about 6 months. It made me gain 40lbs, I lost all sex drive, my mind became foggy and I felt mentally slower. I also got severe anhedonia and became unable to feel the effects of alcohol, cigarettes. I don't recommend this medication to anyone.. I've been off it for 4 months and am still dealing with the side effects of this medication. I will say that it did reduce the voices significantly but only because it's such a powerful mind numbing drug. I would advise to try something else if you really need a medication. Basically a chemical lobotomy."

2 / 10
Was this helpful?YesNo
42 Report
  • kano
  • March 7, 2021

Invega Sustenna (paliperidone) "Invega Sustenna nearly ruined my life. If I had given myself the choice between a life without the capacity to feel or be present while the rest of the world ignored my problem, or manage myself holistically with smaller challenges, I would have chosen the latter. Also note that breast milk develops in most patients and it took nearly a year of removing the drug/pharmaceutical from my system to put an end to that nightmare. Choose what you put into your body wisely."

1 / 10
Was this helpful?YesNo
27 Report
  • pelik...
  • July 15, 2015

Invega (paliperidone) "I was on Risperdal for 3 years, I switched to Invega just over a month ago and am already losing a good deal of weight, I do sometimes get restless but I accept this as the price for not sleeping 17 hours a day on Risperdal, my appetite is normal and I don't eat huge portions anymore, my energy is up and I can actually feel emotions fully again, for the first time in a long long time, would recommend giving this a try to anyone - just remember some people get different side effects, for me this also took away sexual side effects that were limiting my relationships."

9 / 10
Was this helpful?YesNo
56 Report
  • Mimi
  • Taken for 2 to 5 years
  • May 28, 2018

Invega (paliperidone) "Horrible side effects!!! Caused facial hair, missed periods, swollen tender breast, I would produce breast milk though I was not pregnant, severe uncontrolled muscle jerks/ spasms/ changed color of pubic hairs. After a year I still had involuntary movements and spasms. My neighbors assumed I had Parkinson disease."

1 / 10
Was this helpful?YesNo
42 Report
  • Inveg...
  • February 28, 2018

Invega Sustenna (paliperidone) "Warning: this shot will destroy your life. I only had 1 shot, the 234 mg. I dropped out of school, became depressed. It's been 3 years and I still suffer from absence of emotion. It doesn't sound like much but trust me, life becomes empty without emotions. In some cultures, hallucinations are a sign from beyond. People that can hear or see things will often become shamans, medicine men, or healers. I highly reccommend meditation, and/or seeing someone that is an energy healer."

1 / 10
Was this helpful?YesNo
43 Report
  • Green...
  • Taken for less than 1 month
  • May 13, 2019

Invega Sustenna (paliperidone) "I was injected twice Invega Sustenna. I had no sex drive, no emotion, no pleasure for the first three weeks. I was miserable and it lasted 8 to 9 months off the drug. I wouldn't recommend this drug to anybody. I am on abilify maintena now and I am feeling much better. 0/10 invega sustenna"

1 / 10
Was this helpful?YesNo
37 Report
  • Yusaf
  • December 22, 2019

Invega Sustenna (paliperidone) "Gained 40 lbs in two weeks right after taking it. Made me pale (I'm olive complexion). Made anxiety horrible for a few months (could not stop moving around). Messed up sleeping habits for a few months. Stopped my periods for three months in a row. Never had problems with any of these things before taking. Been off for ten months now just now getting back to close to normal."

2 / 10
Was this helpful?YesNo
33 Report
  • Darius...
  • Taken for 5 to 10 years
  • February 24, 2021

Invega Sustenna (paliperidone) "Miserable all the time on this Invega injections from several side effects. I'm mentally blank like poverty in thoughts I'll sit around a lot staring at tv while mindless. I have no emotions except anxiety and akathisia which is chronic restlessness. I take inderal blood pressure medication to treat akathisia. Feel like an emotionless robot going through the motions and barely alive. Poor memory, focus, learning and concentration. Feel physically numb. Gained 40 pounds. No sex drive and no libido. No interest and motivation to do anything."

1 / 10
Was this helpful?YesNo
26 Report
  • Anony...
  • February 1, 2008

Invega (paliperidone) "This drug works great for the treatment of schizophrenia. It has made me feel a ton better, and its benefits far outweigh the few side effects. Be sure to take exactly when you are supposed to and not try to catch up on a dose. I did this and had to go to the hospital for treatment of muscle rigidity and uncontrollable muscle spasms, but as I said it has only happened once and happened when I missed a dose and tried to double up. So this is a great medicine, but take as prescribed only."

Was this helpful?YesNo
83 Report
  • Rose
  • May 2, 2019

Invega (paliperidone) "I have been on Invega for 7 months. I have noticed many side effects like muscle stiffness, agitation, involuntary movements horrific nightmares headaches and I have gained about 40 pounds in that time while continuing to exercise and eat healthily. I was on 9mg for about 3 months and then was lowered to 3mg. It did stop my severe psychosis when initially prescribed so for that I am very grateful. I am now weaning off the medication to hopefully improve my quality of life. Would not recommend unless absolutely necessary."

2 / 10
Was this helpful?YesNo
34 Report
  • cat
  • Taken for 1 to 6 months
  • April 11, 2021

Invega Sustenna (paliperidone) "DON'T GIVE UP. I have autism asperger's ADHD PTSD OCD. I am an artistic recluse with an IQ in the top 1% . I am terrified of doctors nurses + hospitals I was sleepy + tearful. They noted two facts and said I was delusional and deprived me of my freedom. I had 2 injections without a formal diagnosis. The 1st caused anxiety, depression, insomnia, agitation + hyper vigilance. My second in my arm caused extreme pain in neck, slurred speech, frequent drooling, constant pain at base of skull, blood in urine, swelling of ankles and face, extreme physical fatigue and sleeping 15 hours a day. I forgot what I was saying, was unable to spell and was curled in a ball shaking with fear. And a few months ago I wanted to swim out into the ocean at sunrise .. BUT ..i read these stories + knew i just had to wait. I did everything I should as a discipline. I ate though I had to force the food down. I cried for the person I knew I had been - optimistic + resilient + creative + productive. It destroyed me beyond repair . I may never trust a human being again."

1 / 10
Was this helpful?YesNo
23 Report
  • Windoe
  • Taken for 6 months to 1 year
  • September 12, 2022

Invega (paliperidone) "It was and still is an absolute nightmare. I am bedridden since the 3rd shot. I was given this for my first Psychosis episode. I should not have been given it in the first place because I never heard voices I just had strange thought. I have brain damage. My IQ so dramatically reduced that I am unable to live alone. I have very severe anhedonia. I can't listen to music, watch TV or read. I can't sleep. It is like being buried alive. I left the medication 9 months ago with 0 improvement. Only people with severe schizophrenia should be given this"

1 / 10
Was this helpful?YesNo
15 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Schizophrenia

Care guides

Symptoms and treatments

Medicine.com guides (external)