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Orlistat for Weight Loss (Obesity/Overweight) User Reviews

Brand names: Xenical, Alli

Orlistat has an average rating of 7.4 out of 10 from a total of 328 reviews for the treatment of Weight Loss (Obesity/Overweight). 64% of reviewers reported a positive experience, while 18% reported a negative experience.

Orlistat rating summary

7.4/10 average rating

328 ratings from 328 user reviews.

Compare all 38 medications used in the treatment of Weight Loss (Obesity/Overweight).

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Reviews for Orlistat

  • Ult
  • Taken for less than 1 month
  • June 22, 2024

Xenical (orlistat) "I've been on Xenical for nearly a week. Strangely, my stools are no different than before taking it, and my journeys to the toilet are normal. Is this normal? I'm sticking to the 5g fat per 100g rule so I will update later on any weight loss."

10 / 10
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  • Rachael
  • Taken for less than 1 month
  • May 19, 2024

Xenical (orlistat) "I started this drug a week ago after losing 8 kg over 8 weeks through diet and exercise. I need to lose a further 41 kg, so my doctor prescribed it for me. The doctor didn't give me good instructions, and I feel the instructions that came with the pack aren't as thorough as I'd have liked, so I joined a Xenical support group on Facebook, which has been brilliant. I have stuck to three healthy meals a day, stuck to my TDEE recommendation for weight loss, ate less than 15 g of fat per meal (12 g or less to avoid the orange oil disaster!). One tablet with each of the three meals. In the first week, I have lost 4.1 kg, which I am more than happy about. I'm hoping I can continue at a similar pace. I've decided not to weigh myself until my review with my doctor in four weeks. It's been great for me so far, no accidents, no headaches, or stomach cramps. I would say drink plenty of water though, as I have been more thirsty than usual, but not excessively."

10 / 10
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4 Report
  • Best...
  • Taken for 1 to 6 months
  • January 3, 2024

Alli (orlistat) "I have lost 27 pounds on Alli over a five-month period. Mainly, it's aversion therapy. Nobody wants side effects, so you make common sense meal choices. Best success I have ever seen with any diet. I went from 137 to 110!!! I have also never had any extra side effects, like some have mentioned. Highly recommend!!"

10 / 10
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12 Report

Frequently asked questions

  • amanda
  • Taken for less than 1 month
  • November 10, 2023

"My doctor told me I have high cholesterol, and that I was a stone overweight. I have been on orlistat for 4 weeks and have lost 6 pounds. The medication stops you from eating fatty food, and basically if you do, you stink. I love my new diet. I cook fresh, healthy food. I am very pleased."

10 / 10
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0 Report
  • Annam...
  • Taken for less than 1 month
  • September 7, 2023

"I lost 80 lbs in 2 months with this amazing medication. I also made sure I took a good vitamin. I watched what I ate and ALWAYS took orlistat within an hour. I took 120 mg per meal."

10 / 10
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2 Report

Are you taking this medicine?

  • jue
  • Taken for 1 to 6 months
  • May 27, 2023

"I have been using Orlistat since the middle of February 2023. It is now the end of May 2023 and at this time I have lost 17kg. I have some days only taken two tablets but mainly three. The only side effect I found, in the beginning, was if I had too much fat and would have an urgent need for the toilet. On a positive note, my appetite has decreased. If I'm not hungry I have fruit and I don't eat between meals anymore. I feel healthier all over and inches seem to be melting away. I have yo-yo dieted for over 20 years and this has helped. I give it 10/10."

10 / 10
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1 Report
  • Alireza
  • Taken for 1 to 6 months
  • May 13, 2023

Xenical (orlistat) "I haven't lost weight only 0.5 kg but my aerobic endurance improved drastically so I recommend this medicine for visceral fat."

10 / 10
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7 Report
  • Sal
  • Taken for 6 months to 1 year
  • May 4, 2023

"I’ve lost 4 Stone 13lbs so far in 7 months. Had one accident but washing up liquid saved the day and got the orange oil out of my new jeans. I feel fantastic, my skin is better, I had developed obesity-related acne and it’s gone. I’m back in size 14-16 and feel like I can move again. I think this medicine is working for me because it has broken my psychological self-sabotaging barrier to weight loss where one blowout would knock me off the rails. I can have a takeaway, eat chips and enjoy it and then enjoy flushing it all away the next day. So long as it’s not every meal, I still consistently lose weight. I find it so satisfying seeing pools of oil in the loo (sorry!) knowing that’s not in my body and I’ll still lose weight. It’s changed my life, I’ve never lost anything like this amount of weight before, and I’d really recommend it to anyone! :-)"

10 / 10
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8 Report
  • MB23
  • Taken for less than 1 month
  • January 28, 2023

Xenical (orlistat) "Started taking Xenical 1 week ago and lost 7lbs in one week. Haven’t yet had any form of accidents, however I have completely changed my diet to low fat and added 45 minutes of walking 5 days a week. I did experience headaches for a few days, which have now completely passed. I have been eating 1,200 calories daily (roughly) and found this to help. Have also experience constipation if taken with a meal that’s between 2-5g of fat."

10 / 10
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6 Report
  • Anett
  • Taken for less than 1 month
  • November 15, 2022

"I’ve started to use Orlistat couple of weeks ago, and already lost 2kg. One thing you need to keep in mind that you have to follow a low fat diet, otherwise you’ll get the embarrassing accident mentioned in previous reviews. If you use it as it’s prescribed you don’t have to worry about the side effects. I hope it helps."

10 / 10
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4 Report
  • JS2022
  • Taken for less than 1 month
  • October 21, 2022

"I am a woman in my early twenties with PCOS so my weight loss is difficult due to what I’m assuming is hormone issues because my diet and exercise habits are good. I’ve been taking Orlistat for less than a week and I’ve already lost 5lbs with the diet that I have been doing!!! I normally don’t eat fatty foods and I avoid alcohol and sugary drinks. I went out with friends one night and did eat wings. Well… I woke up at 2am regretting every single decision I had made up to that point. I will definitely not be doing that again lol but overall this medication has helped me go from 217 to 213 in a matter of days. I do also regularly work out so I’m excited to keep taking this and see better results months from now. Now I’m convinced it is my hormones that made it difficult to lose weight because I haven’t changed my diet and exercise since taking the pills. So for my PCOS girlies, please give it a try!!"

10 / 10
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5 Report
  • Kat
  • Taken for less than 1 month
  • September 28, 2022

Xenical (orlistat) "Had a good scare with a hemiplegic migraine , which I know is related to my post postmenopausal pounds that packed on. In 2 years I have gained a bit over 40 pounds~ Finally the Dr gave me something to help me and this being my 4th morning of Xenical I am down 7.2 pounds eating 3 times a day Low Cal No Sugar .. No side affects thank goodness. Head is feeling better and I have noticed my achy bones are not giving me such a hard time this morning! Side note : eating roughly 1200 calories and maxing at 26 grams of fat daily no snacking so far."

10 / 10
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2 Report
  • Pudzey
  • Taken for less than 1 month
  • March 11, 2022

"I wrote this to help others looking at review before buying. I have tried all fad diets , never work and I never stick to anything as I can’t control what I eat - I love snacking! Anyway, I brought these off the cuff and wow."

10 / 10
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3 Report
  • Super...
  • Taken for 1 to 6 months
  • February 10, 2022

"Take-home message is that this tackle works, and works well. On the downside, had I known taking a bit of a gamble on an iffy fart while walking around Waitrose would turn out to be quite so catastrophic, then I’d have taken drastic steps. I also wouldn’t have been wearing white rugby shorts. Low point in my life, the ignominy of having to dash to the toilet with turd-oil down my leg was the turning point. I quickly learned that the way to stop making the back of my boxers look like a dropped lasagne was to stop eating the rammal that had turned me into a fat idiot in the first place. Within a few days, each fart became less of a gamble, and each parting company on the toilet looked slightly less like I’d tipped a bucket of Sunny Delight mixed with 5w30 oil down it. Don’t get me wrong, it’s going to be a good while before I have the confidence to show any level of enthusiasm on the trumping front, but I did manage this morning to do one I could hear without washing my gooch."

10 / 10
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204 Report
  • Stacey
  • Taken for less than 1 month
  • January 23, 2022

Xenical (orlistat) "Brilliant from Wednesday to Sunday on this I lost 3.5kgs which is 7lb!! I have none of the bowel problems people have complained about and no issues at all with the medication. I was worried as I usually struggle with new tablets but these are great no side effects for me. For reference I'm 5ft 8 inch and I was 91.5kg and I'm now 88kg in 5 days, obviously some will be water weight but I'm very happy"

10 / 10
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9 Report
  • Molly
  • Taken for 10 years or more
  • November 1, 2021

Xenical (orlistat) "I have been on three 120mg Xenical daily on prescription plus diet and exercise. I have been a Yo Yo for 12 years in good faith, I cared. Xenical has not worked for me, I have not lost any weight or fat. GP cares I care."

10 / 10
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2 Report
  • BellA...
  • Taken for 1 to 6 months
  • October 21, 2021

"Been using Orlistat 120mg for nearly two months. I’m peri-menopausal and nothing was shifting the weight. I’ve lost 1.5 stone, a dress size smaller, and got my waistline back. Yes you poo oil, but if anything, it’s helped with my IBS. I’ve been healthy eating through the week but at weekends, I eat occasional takeaway and treats, I don’t overdo it but I don’t deny myself. No exercise as I’m always on the go so imagine the weight loss if I did! I feel like this medication has been a miracle for me."

10 / 10
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3 Report
  • My re...
  • August 27, 2021

"Orlistat is very good so far I have it after gaining a whopping 3 stone in pregnancy which made me obese I'm 5ft.3 my little one is now 16 months. I mange to loose a stone and a half then it all plateaued and for my BMI I was still classed as obese. I have only had minor sides effects due to only taking 1 a day in the morning ,I will slowly get it up to 3 if I need to. As a single mum I can't risk the side effects just yet. I have been on it for 6 days with making healthier choices and just walking as much as I can and have lost 3 pounds, so I'm very happy and do not feel the need to take more than one a day. ATM I would definitely recommend it gives you that extra boost but if you are worried about side effects just start off small I'm still loosing weight"

10 / 10
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1 Report
  • ladyh...
  • Taken for less than 1 month
  • August 12, 2021

"Orlistat weight loss aid is excellent for those on a low carb high fat diet. I saw that it was working 24 hours after taking my first capsule. If you don't eat fat you won't loose fat with this med, so a high carb diet will not produce good results."

10 / 10
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0 Report
  • Ora
  • Taken for less than 1 month
  • July 21, 2021

"I have started Orlistat only 3 days ago! I have had it prescribed from GP as I can’t shift weight at all tried loads of diets!!! Pleased to say no nasty effects (did noticed the oily stools, have been going to the toilet only once a day max twice) I have lost 1 kg already!! I am fallowing a low calorie diet to so let’s be positive! Scared to eat rubbish as I heard you can have accidents lol! So I have been a good girl and no accidents so far!"

10 / 10
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19 Report
  • Lucky
  • Taken for 1 to 6 months
  • July 7, 2021

"I've been on orlistat since May 2021, and today (July 2021), I got weighed at my doctor's surgery, and I've lost a whopping 2 stone in 7 weeks!! I feel fantastic and will continue to use orlistat to help me lose my weight. I haven't really changed a lot in my diet except I've stopped snacking on junk!"

10 / 10
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175 Report
  • katie
  • Taken for 1 to 6 months
  • June 15, 2021

Alli (orlistat) "I purchased Alli at Target. It worked for me. I have only been on it for 2 months. I went from 238 lb to 226 lb. I am happy with the results so far. I am on the path of getting gastric sleeve surgery, but I might not do that if this continues to take off the weight. As long as I eat healthy, there are no side effects, but I do occasionally cheat and deal with the side effects then. It's no big deal though and worth it to me."

10 / 10
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74 Report
  • Roberta
  • Taken for less than 1 month
  • May 25, 2021

"Was prescribed these on Friday 22nd May 21 to try and help me, alongside slimming world. I had a not so good first week back. I started taking orlistat right away with my Friday evening meal. Ate healthily and walked a lot/stable duties at my yard. I got weighed on the 24th May and I had lost 5lbs with the help of orlistat. I haven't had any really unpleasant accidents etc as of yet. But I do however keep fat content to a minimum. I will update next Monday 31st may results after over a week on it. Overall 5lbs is brilliant to lose first time."

10 / 10
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39 Report
  • Piffer
  • Taken for less than 1 month
  • May 16, 2021

"I have been taking this for just over two weeks and I’m down 9lb, I have just ordered my second month as I am so impressed! It’s a classic case of what came first, the chicken or the egg? I’m so terrified of the side effects I have eaten so well over the past few weeks. I track everything I eat on my fitness pal and I am careful that no meal is over 15g of fat. On the few occasions I have picked at something I shouldn’t, I see the side effects in the morning in the bathroom but certainly not to the dramatic extent some people are describing. Basically, by taking this you are forced to eat healthy or face the side effects. It’s really helped me to develop a much more consistent and healthy approach to food and I really hope that I keep that once I stop taking it."

10 / 10
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13 Report
  • Twin...
  • May 6, 2021

Alli (orlistat) "So one year after having my twins I decided to start losing my baby fluff. Started at 203, got to 191 and hit that first plateau. I took a small break and allowed myself some time to adjust diet and exercise. I got to 186/188. Then I hovered there for FOUR WEEKS. Beyond frustrated. I ordered Alli from Amazon and I take it with lunch and dinner. I have had burgers after a five mile run and an iced nonfat coffee on our trips town. I have not had the serious explosive side affects that have been mentioned but I HAVE had wonderful results. I dropped three pounds two days after taking and that’s when I had the dang burgers! (Plain home smoked burger on a bun btw... not a McGross anything) and I hit 184 the next day. I did not have a crazy bowel movement either. This product will work if you use it correctly."

10 / 10
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30 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.