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Zofran for Nausea/Vomiting User Reviews (Page 3)

Zofran has an average rating of 7.9 out of 10 from a total of 209 reviews for the treatment of Nausea/Vomiting. 74% of reviewers reported a positive experience, while 17% reported a negative experience.

Reviews for Zofran

Commonly mentioned side effects
  • Rae...
  • December 19, 2009

"I have had constant nausea for seven years related to gastroparesis and Meniere's disease (an inner ear disorder causing severe vertigo and nausea). I was finally offered Zofran on my last emergency room trip (I told the doctor if they didn't do something I was going to go insane)... Zofran has been a lifesaver, and I never go anywhere without it. And I mean that. It works like magic every time I need it. The longest it has ever taken to kick in is 45 minutes. I can't say enough good things about it. 100% thumbs up."

10 / 10
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  • IBS...
  • November 25, 2015

"I use ondansetron orally disintegrating tablets that I receive via prescription (8 mg). I only use these on rare occasions when I eat badly, eat too much, or am very anxious, thereby making myself sick. It usually kicks in a few hours after I take it. (They are disintegrating, but I usually swallow them with water because the taste is unappealing to me, but so far, that has not affected its efficiency). Every time as far back as I can recall (and I have been taking this for several years), this medicine has been able to help with my nausea and vomiting. The only times I remember getting sick despite the medicine were when I got upset and cried violently, causing me to throw up. Other than that, I don't recall ever throwing up after taking it!"

9 / 10
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  • Anonymous
  • February 9, 2014

"16-year-old daughter was having headaches and was doing infusions with medications. Used Zofran for nausea. Immediately after it was injected, she had a severe allergic reaction, could not breathe, felt her throat tighten up, shortness of breath, dizziness, anxiety, shivering, and sweating. Oxygen was given, and this passed quickly within 5 minutes. Was observed in ER, and there were no other effects after that episode."

1 / 10
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26 Report

Frequently asked questions

  • I...
  • March 29, 2021

"Zofran is amazing. Absolutely amazing. My entire life, I have feared throwing up. Not sure why, but I now have anxiety because of it. I found out I was pregnant and was slightly nauseous all day, every day, but with someone who fears vomiting greatly, I was scared and upset. My doctor finally prescribed me Zofran after visiting the hospital for nausea, and it has been helping me ever since. I have been taking it for 4 years now whenever I need it, and it takes it away immediately. So thankful."

10 / 10
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  • Eli...
  • Taken for less than 1 month
  • August 22, 2019

"I have taken Zofran on and off for over 10 years. I have been given it after surgery for nausea and vomiting. Also, now again for gastroparesis. Sometimes the nausea and fullness in my stomach are very uncomfortable. Because there are little to no medications or non-invasive therapies, I sometimes will use this to help settle my stomach. While it does nothing for motility, it does alleviate rough times."

8 / 10
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  • Anonymous
  • January 1, 2016

"This medication worked wonders when I had my hip scope back in May. I only took pain pills to sleep, but when I went to shower and sat down after taking my pills, I was so nauseous and took Zofran, and it worked within 5 minutes! I actually used it for a hangover once and it still worked amazingly! Haha."

9 / 10
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  • aaa...
  • Taken for 1 to 6 months
  • March 6, 2019

"Zofran is incredible. I was prescribed it when I started suffering from constant nausea about three months ago, and it has been a lifesaver ever since. It works almost immediately, even after taking it for so long, and has only not worked twice, both times when I had already eaten fatty or greasy foods and had other meds in my system. It can make you extremely constipated, so make sure you're hydrating yourself and consuming lots of fiber, but other than that, I never experienced an adverse side effect or interaction."

10 / 10
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  • sew...
  • June 12, 2015

"Post-op pain medication was making me vomit. After trying several pain meds, it was decided that I should take 8 mg Zofran every 8 hours. The only side effect of this drug was difficulty passing urine after taking it for more than 3 days. We cut it back to two Zofran daily, and that seemed to take care of the side effect."

8 / 10
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  • Zof...
  • Taken for less than 1 month
  • June 28, 2022

"I am having severe digestive issues, and we are trying to figure out what it is. Gastritis? Gallbladder attack? (I do have a gallstone.) IBS? Ulcer? Just don’t know. I have horrible anxiety and stress when something is wrong with me. That probably adds to the nausea. I get nauseous, and it hurts like a gnawing pain. I can’t really eat, it’s miserable. Went to the ER twice, and they administered Zofran, let me tell you! It is a miracle drug! Painful nausea gone! I feel so much more calm, and the gas/bloating is gone. I didn’t experience any effects. Even if I get sleepy, it’s a welcomed side effect after feeling yucky for days! Give it a try!!"

9 / 10
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9 Report
  • Ada...
  • Taken for less than 1 month
  • November 4, 2017

"I got food poisoning and couldn't stop vomiting and having nausea from 3 PM to about 4 AM. I was puking so much and dry heaving that I was puking up blood (YIKES!). I found some extra Zofran in my bathroom cabinet from my doctor from the other month, so I decided to take one 4 mg pill. Vomiting and nausea subsided after 15 minutes of taking Zofran. Zofran, you're a lifesaver!!! Would always like to carry this medication around with me all day if I could. Adam"

10 / 10
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  • Sav...
  • December 19, 2016

"I had my gallbladder removed in September and have been on this drug (as needed) since. It is a godsend. I don't get as nauseated as I was the first month after surgery but still have nausea here and there. This drug works very quickly, and I feel instant relief. Sometimes I find myself needing to take 2 doses if the nausea is severe, and it helps to ease it. Recommend this for anyone that struggles with nausea."

10 / 10
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  • A g...
  • Taken for 1 to 6 months
  • June 24, 2017

"I've been on Zofran multiple times. For nausea and vomiting due to a digestive disorder I had, and when I was pregnant (24/7 sickness for most of the pregnancy). For the pregnancy, it was okay. It took the edge off. Nothing can ever truly 100% help that level of constant nausea, but it kept me from vomiting, so I was able to keep down water and food. For the digestive problem causing sickness, it was a miracle. Gives me a headache but well worth it. Going from feeling so sick to feeling way better. It works wonders."

10 / 10
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  • Fiz...
  • December 13, 2014

"I have been having a lot of stomach issues. I was told it was a bunch of things. At last, it took about 4 months to conclude it was my colon. After a bout in the hospital, I was given Zofran, which worked wonders in no time at all; was also given Phenergan at one point and immediately became extremely irate until I passed out from it. In comparison, Zofran is a godsend. Can be expensive."

10 / 10
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  • GCa...
  • Taken for 1 to 2 years
  • January 15, 2019

"Since childhood, I’ve always been nausea-prone. Sometimes there would be a direct correlation, such as motion (car more often) sickness, overeating/unhealthy eating, etc. Mostly, it just comes out of nowhere and stops me in my tracks. Without insurance, it was very expensive (not sure how much, but $$$). Ever since having insurance and paying a few dollars, I will never be caught dead without a couple tabs on my person! My GI was very understanding and prescribed 60 tabs a month (up to 2 a day) with a generous amount of refills! Only once did it not work, but that was on New Year's, and I believe for obvious reasons! I’ve not really noticed side effects since my nausea throws off my body anyway. I take this med at least once a week. I can’t believe I wasn’t introduced to this sooner! It’s saved my life."

10 / 10
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  • Anonymous
  • October 2, 2011

"Zofran is a lifesaver! Works quickly and very well. I get bad anxiety and worry a lot, which causes recent and sometimes unbearable stomach upset. One pill and I'm good! I am so happy I found relief. It does cause constipation for me, but I'd much rather deal with that!"

8 / 10
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  • Anonymous
  • May 26, 2008

"This really is a lifesaver. I'm 17 weeks pregnant and have crippling morning sickness. So bad that I could not eat or drink anything for over a week. As soon as I took one pill, I became 100000000 times better. I would recommend this pill to anyone. I love it. 10 out of 10 in my book."

10 / 10
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  • Lee...
  • Taken for less than 1 month
  • May 24, 2019

"Wow! I went to the ER on Tuesday night, and it is now Friday, and I was given Zofran for my nausea on top of everything else I was dealing with, and this crap has made me nothing but nauseous with lots of throwing up and constipated! Not sure how long this is supposed to last, but it’s freaking annoying, and I definitely don’t see myself taking this ever again."

1 / 10
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  • Mar...
  • April 30, 2016

"I've been dealing with extreme nausea and vomiting for the past 6 months, and it finally got to the point where I couldn't take it anymore and went to the ER. They gave me Zofran through IV and was feeling better in about an hour. After I was released, I was on 4 mg every 8 hours, and for about a week, I was back to my old self. Then things started to go downhill, and they boosted it to 8 mg. Now it doesn't even work anymore and makes me more nauseous than I was before. I also got pretty bad constipation and headaches after taking the medication. Not to mention, if you're taking the tablets, be ready to handle the taste because it is DISGUSTING."

5 / 10
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  • Joh...
  • Taken for 1 to 6 months
  • October 7, 2019

"So, I suffer from cannabinoid hyperemesis syndrome (CHS) because of smoking pot for the last 5 years, and I have to say, what has helped is Zofran - it is really good at doing what it’s designed to do (helps nausea and vomiting) and eased the tension on my stomach. Been using it for a month every day, 2 hours before smoking whatever, i.e., concentrates or just bud. The ondansetron is miraculous and will literally save you a ton of time since when I was constantly vomiting, I couldn’t do my daily routine (going to work, hanging with friends). Man, I couldn’t even move at all, I was constantly in my bed throwing up..."

8 / 10
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  • Mul...
  • Taken for 1 to 6 months
  • May 22, 2020

"Zofran is a total waste of medication. Literally does nothing for me. Off-brand Pepto does better. My wife has been given it several times in the hospital for the same thing. No results. Seems like the hospitals try to force this particular nausea medicine first. I’m guessing because it’s cheaper."

1 / 10
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  • Bri...
  • February 2, 2016

"Was given this drug while pregnant for morning sickness. Didn't help at all, gave me a headache and actually made me throw up a few times. My son was also born with a genetic mutation - Epidermal Nevus syndrome, which I'm sure is from the Zofran as it is not approved for use during pregnancy. If I could go back in time, I would NOT have used this during pregnancy. I was also given this drug several times for gastroenteritis with the same result - headache and increased vomiting. Did not work for me."

1 / 10
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  • Me ...
  • Taken for less than 1 month
  • November 9, 2015

"Zofran is great for nausea, but watch out for the constipation. I was prescribed 15 8 mg tablets last week and have used one tablet a day since then (about 5 days now), and after waiting, walking, and drinking copious amounts of water, I am going to need to try a suppository or laxative and have my dosage of Zofran decreased to 4 mg. Great medication, it does give me nausea relief, just something to be prepared for, I know I wasn't."

8 / 10
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  • Lor...
  • Taken for less than 1 month
  • July 16, 2019

"I caught a stomach virus last winter and was vomiting repeatedly. I couldn't keep anything down. I was nauseous, dizzy, and feverish. I felt like I was on a moving boat, and I couldn't move or even think without vomiting. After I threw up bile the 2nd day, I went to the ER. I vomited in the waiting room and 3 more times in the exam room. I was given Zofran, which helped a lot. I only threw up 2 or 3 more times after that. I was diagnosed with norovirus."

9 / 10
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  • Anonymous
  • Taken for less than 1 month
  • December 13, 2012

"My daughter was experiencing a constant unexplained ache in her stomach and a feeling that she was going to throw up, that no stomach test could find. Three months later, an MRI showed she had an AVM in her brain. Surgery to repair took all symptoms away. Three years later, she started having the same feelings. Found out the feeling of throwing up was the aura before partial seizures they didn't know she was having. Still having the gnawing ache. One amazing doctor suggested Zofran... it was our miracle. She has been fine ever since."

10 / 10
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  • Bri...
  • June 18, 2017

"I have a variety of GI issues as well as a phobia of throwing up, and ever since I've been taking Zofran ODT, I've been able to function without throwing up in the middle of the night every night. My only complaint would be that after 5 years of taking it, it doesn't work as magically as it did at the start, but it still works wonders."

10 / 10
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16 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

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