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Zofran for Nausea/Vomiting User Reviews (Page 2)

Zofran has an average rating of 7.9 out of 10 from a total of 199 reviews for the treatment of Nausea/Vomiting. 75% of reviewers reported a positive experience, while 18% reported a negative experience.

Reviews for Zofran

  • Patient...
  • Taken for 1 to 6 months
  • March 4, 2019

"This medication is as close to a miracle for anyone with terrible nausea as it gets. Whether you have a flu or are going through chemo. Zofran is amazing. It works on your seretonin receptors; however it is not like an anti depressant. It target a specific function and suddenly, almost instantly in my case; nausea is gone. I thank my lucky stars that this medication exists. For many it is a huge difference maker."

10 / 10
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26 Report
  • icybl...
  • March 13, 2008

"I have had nausea and been vomiting for one year and one month, I am 16 and I have spent 90% of my life the past 1.1 year/mo in bed sick. The last month, FINALLY, after so many medications...THIS, WAS IT. I am still being tested as no one knows what is wrong, that is causing me to be so sick...BUT Zofran has made so I can get SOME relief, I am grateful."

9 / 10
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59 Report
  • Momma...
  • February 1, 2015

"I'm 32 weeks 5 days pregnant. Was admitted into maternity yesterday after throwing up every few minutes all yesterday morning. They have me fluids and Gravol but that only made me drowsy, and did nothing for the throwing up so they decided to give me the Zofran. It started working as soon as it was into my body. It's was quick and very effective!"

10 / 10
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38 Report

Frequently asked questions

  • Natty_R
  • Taken for 1 to 2 years
  • February 23, 2016

"This is such an effective and helpful med. I can't tell you how many times I'd been nauseous and almost immediately got rid of it with the disolvable version. It melts, I wait a few minutes and then it's gone normally."

9 / 10
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34 Report
  • Pat
  • Taken for 2 to 5 years
  • January 7, 2020

"I have tried 3 different forms of Zofran on multiple occasions for 2 different reasons, and it has never helped my nausea at all. I have tried it for both my everyday nausea and my migraine nausea, but I would still throw up. I have tried the medication in the forms of: 1. Swallowing the pill 2. Dissolving the tablet in my mouth 3. Getting it pumped into me intravenously (with an IV in the hospital). Zofran just doesn't work on me I guess! It works really well for some people, though."

1 / 10
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Are you taking this medicine?

  • OLou
  • Taken for 1 to 2 years
  • May 3, 2014

"This medication works wonders for me whenever I feel sick or nauseous. The flavored tablets that disintegrate under the tongue or in the mouth are very convenient and work really quickly to relieve nausea/vomiting. The only real side effect from it that I have noticed is a slight tired feeling. I'd much rather feel a little sleepy than sick to my stomach. I really recommend this medicine if your doctor also feels that it is right for you."

10 / 10
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  • Thela...
  • Taken for 1 to 6 months
  • April 19, 2019

"I was prescribed ZOFRAN a few months back, I have suffered from nausea since I was 17 (I'm 36 now). This is the only drug that has ever worked for me, all the other over the counter meds just make the nausea worse, this makes my nausea go away with in 30 mins. and keeps it gone for 8 hours, I wish this had been around when I was younger."

10 / 10
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  • Joy
  • Taken for less than 1 month
  • August 21, 2020

"I have gastritis and am going through a flareup now. Very sick...nauseous for 8 hours every day. Zophran doesn't help me at all...even doubling dose, as my dr recommended. He is giving me Reglan. Praying that works. Nausea is the worst!"

1 / 10
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18 Report
  • Chris...
  • Taken for less than 1 month
  • April 5, 2016

"I was taking Zofran for awful stomach upset with nausea because one of my other medicines I was on I picked up at pharmacy was a generic new form of medication to treat pain. This new medicine made me very sick. Zofran helped out a lot plus I could take it up to four times per-day. However, I'm also on Lexapro for depression and panic attacks. One day after 2 weeks on these meds I had severe shaking happening to me and I never felt this way before.. Come to find out taking both the Zofran and Lexapro on same day each day was high risk of a drug interaction very severe and I was having the symptoms of a bad interaction. I need to change my lexapro to another type of depression med. But, every depression med is bad with zofran."

8 / 10
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32 Report
  • asbeen
  • Taken for 6 months to 1 year
  • August 22, 2014

"I've had reoccurring nausea for over a year now. The bouts of nausea, dry heaving and vomiting only bile would last for hours. Phenergan did nothing, but Zofran, within 5 min (usually) I'm cured. It does make you sleepy, but well worth a little tiredness. It is expensive without insurance."

10 / 10
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36 Report
  • Bella...
  • November 7, 2017

"This drug has saved my sanity. I was undiagnosed with a debilitating vomiting sickness. In hospital at least once a week via ambulance. Repetitive vomiting and could not stop. To the point where I would become unresponsive. After about a month into my undiagnosed sickness, at the emergency room, a nurse gave me a wafer of Zofran. It was a huuuuge relief as my uncontrollable vomiting stopped within 10 minutes. I had not heard of the drug but after finally been diagnosed, after 6 months, as having Severe Idiopathic Gastroparesis I found my new best friend. As well as having a kidney transplant and taking a bucket full of anti-rejection meds, I was soooo grateful that some smart cookie out there invented this drug. Saved my life"

10 / 10
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  • Anonymous
  • October 10, 2012

"I can't say enough about Zofran. I was curled in a fetal position in front of the bathroom, on the floor, in a cold sweat after vomiting for the last two hours. The last bout was dry heaving. Still the nausea was crippling me. My wife gave me one pill and within 30 minutes the hell I was going through broke like an ocean tide receding. I keep Zofran in the medicine cabinet now, at all times."

9 / 10
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40 Report
  • Kaydubs
  • Taken for 2 to 5 years
  • January 26, 2016

"Zofran is a miracle drug! I've had this medication for several years on an as-needed basis. With my IBS and anxiety, I tend to get nauseous easily. Whatever the cause to my nausea may be, Zofran works every single time. Now that its dissolvable it makes it so much easier to take. The relief happens within 20-30 minutes and usually 1 tablet is all I need. I do experience 2 side effects each and every time: a painful headache after the drug wears off (6-8 hours after taken) and constipation (practically nonexistent bowel movements) for 2-3 days. For the headache, OTC migraine meds work best. The constipation isn't bothersome enough to me to treat."

10 / 10
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30 Report
  • Sugah
  • Taken for 6 months to 1 year
  • October 6, 2019

"I have several chronic conditions and one is called Cyclic Vomiting Syndrome. It's even worse than it sounds. I'm over 40 and have suffered since childhood. Gravol stopped working over a decade ago. Last December was particularly bad with many trips to the ER and I finally got lucky and was given this. It's a miracle drug for me about 95% of the time. I do get some side effects like diarrhea and sweating but they're very bearable. I don't go anywhere without a bottle of these."

10 / 10
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  • Nicck
  • Taken for 2 to 5 years
  • February 4, 2019

"Zofran is THE most reliable medication I have ever taken! It has prevented me from throwing up, or even feeling nauseas 100% of the time! It's sad that when I was growing up in the 1970's, all I could take for nausea was Pepto-Bismal, which NEVER worked to prevent me from getting nauseous or vomiting. Pepto-Bismal is great for diarrhea, but it did NOTHING for my nausea. I can't say enough about Zofran!"

10 / 10
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  • Chels...
  • Taken for 1 to 6 months
  • December 29, 2016

"I used to take Requip for restless leg syndrome, and sometimes it made me so sick I would vomit. Other nights it would be fine. One day I decided to call my PCP for a script of zofran or phenergan to help subside the horrible nasty vomiting and nausea effects of Requip and they wrote me a script of 12 4mg Zofran swallowable tablets. It helped almost immediately (not within a minute, but 10mins or less) and then decided to stop my Requip medication because just made me sick. My RLS went away with other meds that I take and while I still take Zofran, I enjoy it for any spur of the moment "IM GONNA BE SICK" Kind of feeling, so I always carry it with me. At a hospital visit they gave me a dissolvable one that tasted like berries. Good med"

10 / 10
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  • jap
  • March 8, 2016

"I love this medication, it has made such a difference in my life. I was on the Zofran pump while pregnant for hyperemesis gravidarum, it is the reason I was able to carry my child to term. It is the reason we are both here today. I continue to take Zofran as needed for nausea stemming from complications with fibromyalgia, ibs and celiacs. It can cause constipation from time to time, but that is much easier than nausea and vomiting all the time. It melts quickly and within minutes the nausea is gone."

10 / 10
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  • Mommy...
  • October 16, 2015

"Ever since the 5th week of my pregnancy, my morning sickness was terrible I lost weight and couldn't keep a thing down. I could hardly get out of bed. My doctor prescribed Zofran and it's been a huge help. Doesn't always take away the nausea feeling But no more vomiting! Definitely recommend it"

8 / 10
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  • Anonymous
  • March 16, 2008

"The side effects from various drugs, particularly morphine caused signficant nausea. In fact, I'd have to rate the nausea as worse than the actual pain. Zofran worked like a charm, quite quickly, with little side effects (as far as I know). It certainly made my recent visit to the hospital much more comfortable!"

9 / 10
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41 Report
  • Garden
  • Taken for less than 1 month
  • May 28, 2019

"I like the Zofran pills when they actually work but it seems like I have to take a pill, throw up, and then take another for it to be effective. Also I always wake up with a headache once taken. I do want to note that when I was given Zofran in the hospital through the IV I had no issues with nausea it’s only when I take it orally that it does the opposite of what I’d like. All bodies are different and this is just my reaction. I am on a low dose and have not upped the amount I’m taking. $45 dollars for 15 pills (without insurance) and I’ve puked up half of them. Not worth it. Especially when an anti nausea causes nauseous."

3 / 10
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  • Kteel
  • Taken for less than 1 month
  • August 21, 2013

"I have had three pregnancies and with the first two the morning sickness was bearable enough without medication. This time around I have had trouble making it to work and have been constantly miserable, nauseous and dry heaving. I took my first Zofran last night and the only complaint I have is that I wish it was non-drowsy. I almost fell asleep at my desk today. However, I will take drowsiness over nausea any way. Thank you Zofran."

10 / 10
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  • Elina
  • Taken for less than 1 month
  • August 22, 2019

"I have taken zofran on and off for over 10 years. I have been given after surgery for nausea and vomiting. Also, now again for gastroparesis. Sometimes the nausea and fullness in my stomach is very uncomfortable. Because there are little to no medication or non invasive therapies, I sometimes will use this to help settle my stomach. While it does nothing for motility it does alleviate rough times."

8 / 10
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15 Report
  • IBS
  • November 25, 2015

"I use ondansetron orally disintegrating tablets that i receive via prescription (8mg). I only use these on rare occasions when i eat badly, eat too much, or am very anxious, thereby making myself sick. It usually kicks in a few hours after i take it. (They are disintegrating but I usually swallow them with water because the taste is unappealing to me, but so far that has not affected its efficiency). Every time as far back as i can recall (and I have been taking this for several years) this medicine has been able to help with my nausea and vomiting. The only times i remember getting sick despite the medicine was when i got upset and cried violently, causing me to throw up. Other than that i don't recall ever throwing up after taking it!"

9 / 10
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  • Anonymous
  • February 9, 2014

"16 year old daughter was having headaches and was doing infusions with medications. Used Zofran for nausea. Immediately after it was injected she had a severe allergic reaction, could not breathe, felt her throat tighten up, shortness of breath, dizziness, anxiety, shivering and sweating. Oxygen was given and this passed quickly within 5 minutes. Was observed in ER and there were no other effects after that episode."

1 / 10
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  • Rae...
  • December 19, 2009

"I have had constant nausea for SEVEN years related to gastroparesis and Meniere's disease (an inner ear disorder causing severe vertigo and nausea). I was finally offered Zofran on my last emergency room trip (I told the doctor if they didn't do something I was going to go insane)... Zofran has been a lifesaver and I never go anywhere without it. And I mean that. It works like magic every time I need it. The longest it has ever taken to kick in is 45 minutes. I can't say enough good things about it. 100% thumbs up."

10 / 10
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33 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Nausea/Vomiting

Symptoms and treatments

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