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Symproic and Upset Stomach: What Users Say

Upset stomach: mentioned by 4 users (11.8%)

Based on user experiences from 34 Symproic reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

cramps 23.5%
nausea 23.5%
diarrhea 17.6%
constipation 11.8%
upset stomach 11.8%
vomiting 11.8%
abdominal pain 8.8%
bloating 8.8%
sweating 8.8%

Reviews for Symproic

Commonly mentioned side effects
  • Pam...
  • Taken for 1 to 6 months
  • April 22, 2020

For Opioid-Induced Constipation "So, when I first started taking this Symproic, I thought I’d found a miracle drug. Then, the night before last, I got stomach cramps and vomited. Yet, I still didn’t go. Went back to bed, got up like three times, and finally I went. I plan on taking this only if I haven’t gone in several days. These side effects are just awful. I’m envious that some of the people on here have had no side effects!"

5 / 10
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12 Report
  • Jas...
  • Taken for less than 1 month
  • February 10, 2019

For Opioid-Induced Constipation "I was prescribed this medicine by my pain management doc for OIC. Prior to using this for my OIC, I’d try to drink apple juice daily, warm prune juice just weekly, and whenever I could remember, squeeze some Miralax in. My insurance company doesn’t cover this, so I was given a week sample. Then, lo and behold, my insurance company approved a month’s supply. I’ve been taking it daily. At first (maybe the first 3 days), I had the laxative side effects: extreme cramping and stomach aches, but no fantastic movements, just my typical hard-to-pass stools. Now I’m just about a month in, and I feel I’m back to where I’ve started. It doesn’t work for me. I get better results with my natural remedies. I’m younger and have an illness where I will be on pain meds my entire life, so I’m very afraid of laxative dependence, therefore, I was leery to try this at all. Now I regret introducing my body to this medicine for no results. After consulting my doc, I will stop taking it and return to natural remedies."

4 / 10
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14 Report
  • Ray...
  • Taken for 6 months to 1 year
  • August 21, 2022

For Opioid-Induced Constipation "Only medication that works. Yes, I get stomach cramps, but going to the bathroom far outweighs the pain. Highly recommend. 0.2 mg is what I take with my hydrocodone. Sometimes I get diarrhea, then I take it only once a day instead of three times a day. Most of the time, once a day is all that is required. The advantages far outweigh the side effects."

9 / 10
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5 Report

Frequently asked questions

  • Cha...
  • Taken for 2 to 5 years
  • June 2, 2024

For Opioid-Induced Constipation "Symproic has been amazing for me. I only take it as needed because, for me, it’s an all-day event. So I can’t take it when I’m working, otherwise, I would be in the bathroom all day. Towards the end, I get diarrhea, but it’s not bad. I would suggest for those working, try it on a weekend first when you’re close to the bathroom just in case your response is like mine. I occasionally have pretty severe stomach cramps when taking it, but it’s manageable. It takes about two hours to start working."

10 / 10
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2 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.