Symproic and Nausea: What Users Say

• Hap...
• September 9, 2019

For Opioid-Induced Constipation "I have tried Movantix and Linzess (sp?) and I felt like they just caused withdrawal feelings more than helping with the actual issue. I started Symproic about a year ago, and it’s a game changer. After I take it, I don’t feel nauseous or super cramped. It is more of a natural feeling. I have noticed that when I go too long between taking it, I sometimes have to take two for it to really flush me out. I am finally able to go in a way that isn’t worse than the constipation itself. I highly recommend it if you have OIC."

• gym...
• Taken for less than 1 month
• September 14, 2020

For Opioid-Induced Constipation "Symproic has not worked well for me. My insurance company forced me to try it prior to them approving Movantik or Amitiza, and I have never felt this sick or uncomfortable. I assume this is what mild opiate withdrawal feels like. I contacted my doctor to see if nausea, sweats/chills, cramps, diarrhea, and agitation were common side effects. If the point of Symproic is just to send you into withdrawal to induce a bowel movement (which is just severe diarrhea at this point), I guess it works. I could have just gone cold turkey on my pain medications if I wanted to do that."

• Pam...
• February 16, 2020

For Opioid-Induced Constipation "I started taking this three days ago. I tried Movantik a while back, and every time it made me nauseous, and ultimately I would vomit. I did poop, however. The first couple of days I took Symproic, it worked like a charm. On the third day, I did get some cramping and diarrhea, but since I’d barely gone in two weeks, I figured I needed a good cleansing! So, keeping in mind it’s only been three days, I highly recommend. I’ll post again after I’ve used it a while. Good luck!"

• Jay...
• Taken for less than 1 month
• October 25, 2019

For Opioid-Induced Constipation "I took Symproic once, and I ended up in the hospital. My small intestines and large intestines were severely inflamed. After I took it, I had extreme abdominal pain, nausea, sweats, and chills. My gastroenterologist told me never to take this medication again. From my personal experience, I do not recommend this medication. I was in the hospital for 5 days after this. The experience I had was worse than childbirth."

• Not...
• January 18, 2018

For Opioid-Induced Constipation "I had eaten a high-fat small meal prior to taking for the first time - within an hour of taking the SYMPROIC 0.2 mg tablet, I began to feel nauseated, which was escalating - I was on the verge of vomiting for another 20-30 minutes & had begun having quite intense abdominal cramping & pain with sudden intense frequent diarrhea & sweating & significant dizziness & fatigue - I continued to have intense nausea & abdominal pain & dizziness & I could barely keep my eyes open & then sweats & chills. I then vomited intensely 2 times & had 2 more episodes of watery diarrhea & was still dizzy & very fatigued. I have had a headache & experienced some episodes of a heaviness in my chest & vomiting & diarrhea have ceased. I had a significant BAD reaction."

• Fri...
• Taken for 1 to 6 months
• January 22, 2019

For Opioid-Induced Constipation "I have been taking this medication for 2 weeks now, still no bowel movement! Nothing but cramps, nausea, and feeling like I'm withdrawing! Did anyone else do that? I have been feeling terrible since I started taking it. Before, I was using 2 capfuls of Miralax in my coffee in the morning, and it might be a day or two, but when it started, it worked! Along with old school Ex-Lax! Drinking Gatorade with 2 capfuls Miralax in the evening. And it seemed, or I know it worked better than Symproic. On Symproic, I would bloat up so bad I looked 7-8 months pregnant, and I'm female, have had 2 children, and honestly, it felt like I was carrying an 8 lb baby again! I was miserable!"

• Gin...
• Taken for less than 1 month
• September 1, 2018

For Opioid-Induced Constipation "I’ve had extreme constipation for over 5 years now. I’ve tried everything OTC and prescription medications, including Movantik! I had a horrible reaction to it!!! I just started taking Symproic this week. It definitely has great results on cleansing me out, but the extreme cramping will not stop and nauseousness. It’s going on four hours today since I took it, and I’m still cramping. I don’t know which one is worse; constipation for at least a week at a time or these horrible side effects!!!"

• Mom...
• Taken for 1 to 2 years
• May 24, 2023

For Opioid-Induced Constipation "Was taking Movantik for a while and was still constipated for years when my pain management physician asked me to try Symproic a year and a half ago. It began working right away without any side effects; however, after taking it for a year, I began having short bouts of diarrhea, constant nausea, and bilateral flank pain. Last summer, the diarrhea was frequent and at certain times very painful, lasting for days. Then I started feeling sick, and these episodes started occurring every few days. Just recently, I realized maybe Symproic was the cause. I stopped it and went back to Movantik four weeks ago. Since stopping Symproic, I haven't had any diarrhea. But the downside is now I'm constipated again. The Symproic worked well for my constipation for many months, great, then all the side effects started and are just too hard on my body. Is there something else that works for opioid-induced constipation?"