Metoclopramide for Migraine User Reviews (Page 3)

• Babyg...
• July 25, 2014

Reglan (metoclopramide) "I have a history of migraines and Reglan, Benadryl and Toprol always works for me. My migraines seem to always be at night and wake me from sleep, I usually use an ice cube (plain not covered on temple) and it works. Really bad ones require the above combination and puts me to sleep all day when I return home from ER. Also my eye loses sight in bottom half/top half or complete eye for a few mins which I found out is a retinal migraine, which is strange because there is no pain at all with that one."

• AAano
• Taken for less than 1 month
• June 11, 2017

Reglan (metoclopramide) "Went to the ER for high blood pressure and was having a bad headache as well. Was given regalin cocktail and afterwards I have had the worse anxiety ever. I wanted to rip the I've out of my arm and run out of there. I will never let them give me those meds again."

• Kaleb...
• May 22, 2021

Reglan (metoclopramide) "I suffer from hemiplegic migraines and had a very bad attack yesterday late morning. I went to the hospital where I was given IV push of Benadryl, Toradol, and Reglan. As soon as she started the IV and walked out of the room I had a horrible feeling come over my whole body. My legs felt like they were on fire and I felt as if I was going crazy. I tried to relax and shake it off but the feeling wouldn’t go away and I became dizzy and almost delusional. I called my wife to tell her what was going on and she told me to hit the call button so I called the nurse back in and told her how I was feeling and she said the Reglan has that affect on some people. She pushed Ativan to counteract it. It was a scary feeling"

• Migra...
• Taken for less than 1 month
• February 25, 2015

Reglan (metoclopramide) "So glad I looked up these reviews! I had the same experience as others with the anxiety, wanting to crawl out of my skin feeling. I had the Benadryl as well, but it didn't help. The doctors and nurses were acting like I was crazy and like they had never heard of this reaction. I'm glad to know I'm not alone and that I wasn't imagining these symptoms. I literally could not lie in the bed - I was pacing around the hospital room, and actually had to jump up and down because I was so restless. Absolutely awful feeling - I'd almost rather have the migraine (almost, but not quite). They finally had to give me Ativan to help. The Reglan did get rid of my migraine though, that's why 2 stars. "

• Blari...
• Taken for 5 to 10 years
• May 4, 2015

Reglan (metoclopramide) "I was diagnosed with "Chronic Migraine Disease" 18 yrs. ago. I have tried too many medications to list. Almost all of which have not worked for me. About 9 yrs. ago during a trip to the emergency for a migraine, I had the worst nausea. I was given Reglan for the first time. Not only did it stop the nausea, it calmed my migraine down! I wasn't even given any Dilodid. I couldn't believe it! I was later perscribed Reglan along with Maxalt. This combo worked the best for me. However, my doctor quit using Maxalt. So, while searching for new meds. my doctor gave me a prescription of Reglan to at least help with the nausea. Not only did it help with that, but if caught early enough, it would stop my migraines. I love Reglan!"

• K8T
• December 8, 2017

Reglan (metoclopramide) "I had a severe migraine for several days. Norco & Fioricet, weren't even touching the pain. Finally gave in and went into the ER. They gave me what they called a cocktail including Reglan & Benedryl. Nothing that was actually intended for pain, but I was willing to try anything so I didn't comment. That was the day I experienced my first ever panic attack. I couldn't vocalize what was wrong, I was hot, thrashing & grasping at my IV, my heart was racing and thought I was actually dying. It sounds so dramatic, but there really isn't words to describe the feeling of the moment that you believe your life is ending. Those of you who suffer from panic attacks- you have my respect & sympathy. Traumatized from Reglan. Never again!"

• Anonymous
• April 7, 2014

Reglan (metoclopramide) "Went ER on Saturday got Reglan, Benadryl and Toprol, along with a bag of saline. Yummy combination, knocked out my migraine and me. Slept for an hour in hospital then another 4 at home. I'm still wiped out but after a doozy of a migraine I am exhausted for at least 5 days post. Almost like a hangover."

• Kat
• Taken for less than 1 month
• September 5, 2017

Reglan (metoclopramide) "Do NOT take this medicine. 1 time IV dose. Causes nervous system damage. First Parkinson side effects, then anxiety after 5 months NOT gone. Possible sensitive to other medications. Horribly traumatic. Couldn't work."

• Ebby
• Taken for less than 1 month
• April 21, 2018

Reglan (metoclopramide) "I will never in my life allow this to be administered to be ever again in life. On 04/20/2018, I went to the ER for a severe Migraine. The RN gave me a cocktail of to toradal and then the Reglan. About 30 seconds later the nurse walked out and I began to experience a strong intense feeling of fear, anxiousness, and anxiety. I wanted to rip the IV out of my arm and run all the way home. I never want to feel like that again...NEVER!!!!!!!"

• MahaZ
• March 31, 2015

Reglan (metoclopramide) "I don't have a history of migraine but I had sever headache for 3 days so I went to ER. After doing some scans they gave me Benadryl, toradol and Reglan by IV. As soon as Reglan was injected I had severe reaction to it within seconds and I couldn't move, I couldn't talk, I was literally paralyzed. I could hear people talking but I wasn't able to respond and my heart rate went to 150 bpm. It was the worse feeling ever. They had to give me an antidote to reverse the effects but it still took almost 3 hours for me to actually speak again. After that day I personally do not like Reglan and how dangerous the side effects can be."

• NuJer...
• November 10, 2015

Reglan (metoclopramide) "I've had a headache for a little over a month followed with nausea. However yesterday there was some pressure with it so I went to the ER. At the ER I was told that I would receive a migraine cocktail, which was Benadryl, Reglan, and IV fluids, not knowing what to expect I accepted. As soon as I was given the medicine through my IV I immediately began to feel jittery. My legs started shaking, it felt like something was crawling on me, and then I got extremely sleepy. I kept falling asleep but every time I woke up I had some serious anxiety. I never want to experience that feeling again. And what do you know today my head is starting to hurt again."

• Kam
• Taken for less than 1 month
• June 22, 2019

Reglan (metoclopramide) "Omg where do I begin. Was in the emergency room for severe migraine and nausea. They gave me this drug through my IV. Never again. I began to sweat, I started cursing and screaming, I was so anxious and delirious. It was a terrible experience. I feel like I needed to just run out of the hospital. Do not recommend."

• Same
• February 27, 2019

Reglan (metoclopramide) "I was in ER last night for severe migraine attack. The doctor asked what I normally get and that's toradol, zofran, and steroid through IV. They come in with this toradol, reglan, benadryl mix. Literally 2 min after meds were administered I felt the need to jump out the bed and just go home. I was burning up inside, restless, and still had the headache. So when I see other people posting almost the exact same thing, I totally get it. The national headache society did a study, benadryl is actually one of the drugs NOT recommended to treat migraines. I was told Reglan treated the "pain". Nope, it actually just controls the nausea by getting your stomach to empty / process the contents faster. I had the same migraine when I woke up. Now the toradol I know helped, it usually does to some degree. But getting a steroid shot / injection is usually what keeps the migraine from returning. Personally, I just don't think the doctor had a lot of knowledge regarding treatment of migraines."

• Quisha
• September 22, 2017

Reglan (metoclopramide) "Given IV with toradol & Benadryl. My headache went away almost immediately . Soon after that I started shivering and trembling. I dismissed it thinking I was just cold because of the hospital temperature & the IV fluids. I also had to pee so bad that I unhooked it myself because I could not wait on the nurse to come in and help me. I was so restless and anxious that I drove home, knowing the nurse told me to call a ride, but it's like I couldn't control the urge to just make it home and go to bed. I didn't realize that all of those symptoms were side effects of the medicine until I got home & started to tremble more & was unable to sleep. Since then I've been having panic attacks & anxiety, muscle stiffness & twitches. DO NOT TAKE"

• Anonymous
• October 9, 2010

Reglan (metoclopramide) "I was just given Reglan this morning at the ER but don't think they combined it with anything but saline. Usually I get the physically "hyper" feeling but with mind exhaustion with Dramamine or Benedryl. Those medicines make me feel like all my muscles need to be repeatedly stretched and like they are itchy on the inside. Luckily I did not get this feeling at all today with just the intravenous Reglan. Even managed to sleep through half the drip. Only bad thing was that it was really cold going into my arm...my whole arm felt numb. Also, don't know if it is common or not, but was starving 6 hours later and ate more in 1 sitting than I ever before (I'm sure I will regret that tomorrow)."

• Beann...
• Taken for less than 1 month
• June 26, 2022

Reglan (metoclopramide) "I'm not kidding when I tell you this medication made me feel a way I never want to feel again. I have since listed this medication as an allergy because I refuse to go through what this medication put me through. I was losing it inside the ER after being given this. Could not sit still and wanted to rip my IV out. I would have rather felt a migraine/nausea than be given this. Would not wish this medication on my worse enemy. Very jittery and uneasy throughout your body.Please be advised."

• LayBan
• November 30, 2016

"I went to the ER with a terrible migraine. No warning of side effects, and while I was anticipating relief from the migraine the complete opposite and possibly even worse happened..It started with a little fidgeting and not being able to get comfortable in the hospital bed, and then I went from 0 to 60 as far as a freak out. I have never felt like that before my life and it was quite possibly the worst feeling ever. I was alone in the hospital because my husband had to be home with the kids and it was so frightening. I wanted to crawl out of my skin,my heart was racing and I was clawing at my face,and I had uncontrollable full body movements.I wanted it to stop and all I kept asking for was help and for someone to make it stop. NEVER AGAIN!"

• Chels...
• January 8, 2017

Reglan (metoclopramide) "Visited the ER due to intense migraine lasting 7 days with 4 impacted wisdom teeth coming in. Face swollen, migraine and intense anxiety went to a different hospital and was hoping for something that WORKED, But got the reglan/benedryl cocktail which made me freak out like a idoit and I cried for anxiety meds when a new doctor came in and denied me anything else and called me a pill popper, although the only meds I'm taking are for my teeth pain (antibiotic and a steroid) and also continued to be rude while still having an outrageous migraine. Home now...hours later...with a migraine still......"

• Nelly
• March 18, 2016

"I thought I was the only one this anxiety attack happened to. I went to the ER for a migraine. I was given Benadryl, Reglan and Toridol. I felt a burning feeling, then a sudden high. Next thing you know my heart start racing I was so scared Was shaking from being extremely cold. When I called the Nurse he looked at me as if I was crazy. I prayed myself to sleep. Horrible experience."

• No way
• June 17, 2016

Reglan (metoclopramide) "Had a myelogram on a Friday. By Sunday I had the worst headache in my life! Tried to get through the pain but by Monday morning I was told to go to ER. I told them I had a spinal headache, not my typical migraine. They gave me IV fentanyl which calmed it for 20 minutes. They then gave me the 'cocktail' of Benadryl, Reglan, and Toradol. Within minutes I was shaking violently and couldn't control it. It made me so nauseated. I thought I was going to either have a seizure or a heart attack! It didn't give me any relief at all- not even sleepy. After several unsuccessful pages to anesthesia for a blood patch, I said I had enough and wanted out of there (after more than 6 hours in the ER)."

• Anonymous
• August 21, 2009

Reglan (metoclopramide) "Like the other anonymous user, I went to the ER with a migraine. I received this medicine and Benadryl (Diphenhydramine) intravenously. The side effects were intolerable. Within minutes of injection a combination of agitation, nervousness and anxiety overwhelmed my already throbbing head. I felt trapped, as if there was no escaping the discomfort of the side effects. I gave this a 3/10 because it still prevented me from throwing up after I already had several times. It works, but I won't ever use it again. I know it wasn't the Benadryl as I have taken it since without incident."

• Anonymous
• July 16, 2017

Reglan (metoclopramide) "I've been to the ER for migraines too many times to count and have been given every kind of drug that can be given. I woke up this morning with a horrific migraine and vomiting and off I went. They gave me the Reglan/Benadryl combo and within less than a minute the pain was gone. I COULD NOT BELIEVE IT! I've never had anything to work so well and so fast. I went home and slept for four hours afterwards. I'm so glad they decided to try this with me."

• Red...
• Taken for less than 1 month
• April 30, 2014

Reglan (metoclopramide) "Had a migraine for three days that escalated and went to the ER. They have me Reglan with saline. Not only did it do NOTHING for my headache, it put my Restless Leg Syndrome into overdrive affecting my entire body but wouldn't prescribe anything for that. They attempted to flush it out with more saline to no avail. They eventually gave me Fiorecet and that at least helped, though didn't stop, the migraine. "

• Queen...
• Taken for less than 1 month
• June 9, 2023

Reglan (metoclopramide) "I don’t recommend it at all! I went to the ER due to extreme symptoms from a migraine and they gave me this. Not even a min later I went absolutely insane!!! Even got arrested at the hospital! Doctors obviously didn’t realize that what they gave me is what caused me to have this reaction. When they tried to give it to me again I advised them of the adverse reaction and legal problems I now had because of it.. so it is listed in my file to not give to me but still. Save yourself the issues that come with this medication."

• JadRN
• March 6, 2017

"I'm an ER nurse. We use a cocktail of 20 mg metoclopramide with 25 mg diphenhydramine. That's 2 vials of reglan and 1/2 vial of benadryl in a 250ml NS bag. Reglan is the primary medication in this cocktail, benadryl is given to reduce the side effect known as akathisia. Both reglan and benadryl causes drowsiness, hence only half a dose is given. 250ml saline bags are used so we can control the rate of flow of the medication (to infuse slow over 20 minutes, we don't use an IV pump with these medications). Ketorolac is optional. If not given correctly, in most cases infused as a bolus/wide open. This is where the problem occurs. I would say It has a success rate of 80%. I've seen akathesia just twice, I give it cautiously every time."