Metoclopramide for Migraine User Reviews

• Mil...
• October 30, 2020

"DO NOT TAKE THIS MEDICATION!!! The doctors gave me this medication without explaining to me the common side effect of basically going insane for a short period of time. They just told me I would feel 'weird' for a little bit and then it would go away. They didn’t even ask me if I had a history of mental illness. I was expecting to feel drowsy or sleepy or a bit off because that’s what feeling 'weird' is supposed to feel like. But no!!! I suffered temporary insanity!!! Extreme derealization, depersonalization, depression, hopelessness, my life felt meaningless, I felt like I was dying and kept thinking about how I did not want to die!!! I felt doomed!!! I wanted to jump out of my skin and run out of the hospital!!!! I was about to rip the IV off my arm. Tremendous emotional despair and near-death experience!!! It was a nightmare while being awake!! I would much rather have the migraine!!!"

• Jac...
• Taken for 1 to 6 months
• January 15, 2020

"Ok, my experience is just the same as everybody else's on this site. I went to the hospital for some stomach pain, and they gave me Reglan through the IV. I got paralyzed in my arm and body, I couldn't move, I couldn't talk. I just wanted to scream, I felt like I was dying. I never had a panic attack in my whole life until that moment. I couldn't breathe, I couldn't dial my husband's phone number to tell him that I thought it was the end for me. That's how bad I felt. It was like I was really passing out, and my heart was coming out of my chest. This happened about 4 months ago. Now the problem is that since then, I have anxiety almost every day for no reason, panic attacks for no reason. I feel agitated and always have the fear that something is wrong with me, afraid I may pass away and leave my kids behind. Did any of you experience the same thing as I am and can't get out of this anxiety? Please send me some answers. If the side effects persist for a long time, what can I do to go back to normal life again?"

• Car...
• Taken for less than 1 month
• February 10, 2021

"Worst experience of my life, it was almost fatal. Literally, my nurse began crying as I was in and out. I suffer PTSD now because of this experience and am scared to go to the hospital, take medications, and especially the ER. Went in for a headache that was persistent, no other symptoms, a healthy young 23-year-old and had such a bad reaction from injecting this stuff into my veins within 10 minutes of showing up. Makes you question their practice and intentions."

• Jen...
• May 20, 2020

"I went to the ER for a migraine. They gave me a migraine concoction, and after they put it in my IV, I started having the scariest panic attack of my life. I suffer from an anxiety disorder and panic attacks, but never this extreme. I kept feeling as if I was dying and I kept telling the nurse I don’t want to die. I could not shake the feeling or calm down no matter how hard I tried and was extremely drugged. They gave me a whole bunch of Benadryl to counteract and told me it has anxiety-inducing reactions on some people! I told them before they administered that I have an anxiety disorder, and they still gave it to me! It took me almost an hour to calm down! I do not recommend it!"

• han...
• Taken for 1 to 6 months
• April 7, 2020

"I went to the ER with a migraine so bad I couldn't even walk. I got hooked up to an IV that gave me the “migraine cocktail“ (Reglan, Benadryl). I felt the most terrible anxiety I have ever felt in my life. I felt like I was trapped. I kept twitching and fixating on the IV in my arm. I begged and begged and begged for them to take it out. I was prescribed Reglan alone to take when my migraines got bad again. I didn't know it was the Reglan that made me feel this way at first, so I started taking it when I felt a migraine coming on. I will never take this medication again. It is the most terrible feeling in the world. Your heart races and you feel like you're being held down, like you are being put in a near-death scenario. I hate you, Reglan!!"

• Sam...
• October 27, 2019

"I went to the ER complaining of a migraine. I was put on Toradol, Benadryl, and Reglan. I have gotten Toradol shots for my migraines over the last couple of weeks with absolutely no problem whatsoever. I also have never had an adverse reaction to Benadryl in my life. So I know the Reglan is to blame. Within 5 minutes of this drug polluting my veins, I felt an insanely strong urge to rip my IV out of my arm. I got extremely restless, like I had to keep moving. I felt like I needed to leave the hospital immediately and was in a total panic. I couldn’t sit still, I just felt like something terrible was happening. This drug definitely induced an anxiety or some sort of panic attack. I do not recommend this at all."

• 342...
• Taken for less than 1 month
• June 13, 2023

"OMG! Reading the comments explains a lot. I went to the ER for a cluster headache. I was given a migraine cocktail with Benadryl. For some reason, the doctor decided to give me Reglan after. Within 10 minutes, my heart rate monitor was going crazy, and I thought I was going to die. They rushed me in and did an EKG, and I remember thinking I thought you passed out when you died. They had also numbed my eyes shut with drops, so I couldn't hardly open them while my heart rate was at 160 for like an hour. I developed such terrible anxiety with IV meds that traumatized me because of Reglan. Never again will I take this drug."

• Mar...
• Taken for less than 1 month
• August 25, 2022

"Never take this. This was given to me in the hospital for a migraine. I had a horrible anxiety attack and thought I was going to die. I have been severely depressed since then and have horrible anxiety. Anyone else feel this way?"

• Rer...
• Taken for less than 1 month
• February 7, 2020

"I am so relieved to find out that I am not alone with these reactions to Reglan. I had a similar reaction once before, so this time I begged them not to give me the Reglan, but they reassured me the medication wasn’t the issue. I pulled out my IV and checked myself out. Why isn’t this kind of reaction known of in the ER?"

• Jes...
• Taken for less than 1 month
• September 26, 2019

"I went to the local quick care emergency room with a severe headache and pain. I was having nausea as well. They came in and gave me a dose of IV Reglan, and within seconds I was freaking out, trying to pull my IV out and yelling that I needed to get out of there. I was dizzy, disoriented, and felt like I was on some serious drugs. I was having severe anxiety, and I felt like my heart was going to explode. I have never reacted this way to any drug, and it was a terrifying experience. I would not recommend this POS medication to anyone, please be careful, especially if you have preexisting anxiety!!"

• Sal...
• January 31, 2020

"Had a headache for 4 weeks. Very severe. Tried everything OTC. Went to ER. Dr. gave a migraine cocktail with Reglan and Benadryl. I weigh 130, 5'6. I immediately started feeling ridiculous anxiety, shaking uncontrollably. Short of breath, feeling like I was going to pass out, and my heart rate was dropping. I felt like I was going to die. I couldn’t even talk to my husband on the phone. Wanted to rip out the IV. I actually stopped the IV and hit the button for help. They had closed the door and I got severe panic. Once the IV was done, they gave me Valium, which helped a little and sent me home. Still had the headache slightly. Have some side effects in the evening and now today. How long does it take to wear off? Awful, awful experience."

• Sop...
• Taken for less than 1 month
• August 30, 2022

"This drug is horrible! I went to the emergency department due to a post-COVID migraine that was so bad, I thought I might be having a stroke. They put this drug in the IV to help with the nausea. I’d never had it before and wasn’t told the potential side effects. Within ten minutes of starting the IV, I became agitated and began thinking of harming myself. I had no idea it was from the drug and only knew that I needed to leave the hospital so I could harm myself. Of course, I did not tell anybody that! I just told them that I was feeling better and needed to leave right away. A nurse came and removed the IV so I could leave, and within minutes, the intense thoughts and agitation subsided. I didn’t know what had happened to me until I got home later on and looked up the side effects of this drug. Even worse, if I had completed suicide, everybody would have thought it was me and not because of this nightmare drug. Terrifying to think how many this has happened to. Please stay safe."

• She...
• August 22, 2015

"I wouldn't even give this drug a 1. I came to the ER last night for severe head and neck pain, and this is what they suggested giving me in an IV: Reglan and Benadryl. I had this once a year or so ago and had a terrible reaction and insisted I didn't want the IV. However, I ended up letting them talk me into it and got it. Within 5 minutes of getting the IV, I felt anxious, trapped, paranoid, like I was going to die. I had to page the nurse like 3 times to come take the IV out. I just wanted to go home. I ended up pacing and walking 20 laps around the hospital with a nurse. They ended up talking me into allowing them to give me Ativan and more Benadryl to reverse the Reglan. I truly felt like I was going to die."

• Sca...
• September 11, 2019

"I was just given this medication through IV for a migraine the other day. It only took moments and my heart started instantly racing, my legs felt super heavy like I couldn’t move, my face was tingling, and I felt like I couldn’t breathe. It was to the point where I couldn’t even talk just scared that I was dying. I was then given Benadryl and with 15 min the symptoms subsided. I cannot stress enough how real it was and how it was the scariest experience of my life."

• lil...
• Taken for less than 1 month
• May 30, 2023

"Caused immediate dystonic reaction, hallucinations, derealization, depersonalization, agoraphobia, monophobia, daily panic attacks, severe depression, akathisia, legs stopped working, muscle tremors, severe fatigue, chills, fainting, diarrhea, nausea, dry heaving, loss of appetite, acid reflux, shortness of breath, red burning skin, numbness in limbs, headache, restlessness, chest pain. Was given this drug via IV one-time dose! It has now been 6 months and I am still completely disabled, feels like I'm living in a dream, scared all of the time, can't eat, no joy, suffering for months on end. I’ve heard it can take a year or more to recover. Please join the Reglan Support Group on Facebook if you are suffering long-term effects from this med and don’t let doctors gaslight you! Keep in mind I have no history of mental illness and now have similar issues to TBI and severe panic disorder."

• Van...
• Taken for less than 1 month
• December 16, 2019

"I went into the ER with a severe migraine, and I was given what they call a migraine cocktail. I told them before I was given the medication that I suffered from an anxiety disorder. They did not tell me that Reglan's side effect was anxiety. As soon as the nurse injected my IV, I felt a horrible anxiety attack, it lasted for hours. I felt so anxious and wanted to run out of the hospital. Please make sure you know what you’re getting. I’d rather have a horrible headache than that. This medication is dangerous."

• Rwd...
• Taken for 1 to 6 months
• January 11, 2016

"Anytime you go into an ER with a migraine, the doc will automatically try to avoid real meds and instead says, 'We're gonna try Reglan,' which has a sedative effect, and then add Benadryl and knock you out, turn off the lights, and close the door for dark and quiet. Good thing for any kind of headache. About thirty minutes later, the doctor rushes in, flips on the light, and says, 'How's the headache?' At thirty minutes of sleeping, you're just starting to hit REM. You're groggy from the sedative effects, therefore, not thinking clearly, so you answer like, 'Um, okay, I guess.' 'Great, let's get you outta here.' On the way out, as you're waking up, you realize the pain is still there, but too late. Reglan is great for the doctors but does nothing for the patient."

• Anonymous
• May 12, 2018

"I went to the hospital for hypertension, which caused an excruciating headache. I was given Benadryl + Reglan and almost immediately started to feel strange. I couldn’t sit still, I got hot and sweaty, and wanted to stand up, but I couldn’t due to the IVs. I was screaming to unhook me and just wanted to leave. I couldn’t shake the feeling that I needed to go home. I felt like I was dying. I became paranoid and anxious to the point I ripped the IV out of my hand-blood was dripping everywhere, and the sight of it made me vomit. It was a huge mess, and I couldn’t calm down. I finally just ran right out of the hospital and went home. Now I know by reading it was definitely a reaction to the Reglan, and I am definitely adding it to my drug list of absolute intolerance. It didn’t take my headache away and caused the worst panic attack I have ever had when I don’t have a history of panic attacks. Seems to me you should be warned about these types of side effects beforehand."

• Anonymous
• February 27, 2012

"Was given this for a severe migraine, along with saline in a drip. After 10-15 minutes, I was 100% better and wide awake, ready to go, and not in an anxious or wired way, just felt ready to go home and pick back up my night. Nothing ever has worked this fast for me, and I've been to the ER for migraines many times in the past. This was by far the best medicine given to me, and I had no side effects whatsoever. 2 thumbs up for this medicine!"

• Dan...
• Taken for less than 1 month
• September 13, 2019

"So just last night, I went to the hospital for a virus accompanied by a migraine. The doctor decides to give me a Benadryl and a shot of Reglan. 3 to 5 minutes after the Reglan has set in (I know it was the Reglan because I take Benadryl no problem), I go into a full-blown panic attack. I have this complete sense of dread. I felt as though if I didn't get out of my own skin, or just that hospital, I felt I was going to die then and there. I honestly don't think actually dying will be as bad a feeling as this. I ripped out my IV, there was blood flinging everywhere along with the fluids that were dripping in. The doctor runs in, yells at me, then goes out and slams the door behind him, which totally intensified my panic, and I ran out of the hospital. The whole way home, I just kept thinking I wouldn't survive to see my kids again. It felt like an hour drive, and it was literally 5 minutes. Never again."

• eha...
• Taken for less than 1 month
• May 17, 2021

"I shared the same feeling of panic after receiving an IV push of Reglan. I never had panic disorder before, but now I can’t get rid of it. I really want to get the COVID vaccine, but this experience is really making me nervous. Has anyone else who had this reaction received it?"

• K_W...
• November 24, 2009

"I was given this in an IV (along with Benadryl) in the ER when I had a horrible migraine. The nurse said it would make me tired when she gave it to me at 4 pm. Well, I was tired for about 3 min., then the 'fun' began. Like the other poster, I started to feel extremely anxious. I kept tossing and turning in the bed because I felt like I wanted to crawl out of my skin. I had to wait for 2 IV bags to finish before they would let me leave. When I got home, I was exhausted but at the same time could not sit still to save my life. I had that 'wanting to crawl out of my skin' feeling all night as I paced the house exhausted. I was finally able to fall asleep at 5 am. The next day I was really shaky and still a little bit anxious."

• Cas...
• Taken for less than 1 month
• November 4, 2021

"11/2/21 I had a terrible migraine, went to ER, they gave me a cocktail for migraines. I wasn’t told the side effects. As soon as the Reglan, Benadryl, Toradol was put in my IV… It was the worst anxiety I’ve ever felt. I instantly wanted it out of my system. A day later and still anxious. I would rather have a terrible headache than those meds any day."

• She...
• Taken for less than 1 month
• February 17, 2017

"I went to the ER for extreme neck and head pain. They said they were going to treat me with a headache cocktail. The nurse shot 3 medicines in me quickly. The first was Reglan. Immediately after she put this in my IV, I felt an intense pressure in my chest and I could barely breathe. I began to feel so restless and jittery. I wanted to jump up and rip the IV out and run. I tried to lay there and calm down, but I felt terrible intense anxiety and worried I was going to die. I felt panic like never before. I thought something was wrong with me, I'm so glad I'm not alone. I'll never agree to this medicine again, and my head still hurt when I left!"

• Mic...
• Taken for less than 1 month
• December 1, 2016

"Due to chronic pain, I take a lot of meds to begin with. I ended up in the hospital with a severe migraine that I'd already had for a few days (among other things). Morphine wasn't helping, not even Dilaudid helped. I don't know who made the switch, but finally at the end of the second day, a nurse came in to give me the Reglan, Toradol, Benadryl combo. Oh, how I loved her after that. It burned slightly going into my IV (but Potassium burned a hell of a lot more), but that was really it. I didn't feel jittery, but it's the usual initial feeling of light-headedness and warmth. It didn't last long, and within a few minutes, my head was starting to feel better. I was surprised this worked so well."