Glucophage and Diarrhea: What Users Say

• Lil...
• Taken for less than 1 month
• January 26, 2014

For Insulin Resistance Syndrome "So far, I have been on Glucophage for 2 1/2 weeks for Insulin Resistance due to Polycystic Ovarian Syndrome. I had a little nausea and diarrhea the first two days. By day three or four, I had no more negative side effects. It worked very quickly, I quickly began to lose weight and started menstruating again. My skin also began to clear up within the first week. Glucophage helps so many of the terrible issues caused by PCOS. I need more time to better evaluate the medicine, but so far it is like a miracle. If it is taken with food, the side effects are negligible."

• Lit...
• Taken for 2 to 5 years
• March 27, 2015

For Type 2 Diabetes "Metformin (Glucophage generic) works very well without any side effects (maybe a small bit of diarrhea and gas - but that helps get rid of my constipation). I am NOT overweight. In great shape with running, playing tennis and golf, etc. Age 65. Never was overweight. Got diabetes from drinking way too much Coca Cola and eating too much sweets (donuts, cake, candies, etc.). Always burned off the sugar so never put on weight. Never knew sugar was a poison that affects metabolism. Started taking metformin (3 X 800 daily dosage two years ago). With diet changes, brought down my blood glucose level from 358 to 130, and A1C from 15.9 to 6.7. Not out of the woods yet, but huge improvement, and metformin is the only drug that works for me."

• Pow...
• Taken for 5 to 10 years
• June 2, 2019

For Type 2 Diabetes "I was taking Glucophage for a number of years, and the only side effect was diarrhea at least 1 to 2 times daily. It kept my blood sugar in the low 100s. I finally lost about 60 lbs, and I no longer have diabetes even though my grandmother and mother had type 2 on insulin, and my brother now has it."

• Anonymous
• February 6, 2012

For Type 2 Diabetes "I've been taking this medicine for a month today. I have seen a significant and favorable drop in my blood sugar. However, I've never felt sicker in my entire life. Every day since starting this, I've been nauseous, even to the point of vomiting. I find that I now have motion sickness and since I take public transport, I sometimes have to get off the bus to vomit. I always have diarrhea. I sometimes have fever symptoms, chills along with a feeling of being very cold, and terrible headaches. I've also become quite anxious, restless, and moody, which may be a side effect of these side effects. I've lost 12 lbs and I find myself eating less, which is awesome but I'm ALWAYS nauseous, which is why I have no appetite."

• Anonymous
• March 28, 2012

For Type 2 Diabetes "I had diarrhea, nausea, vomiting, headaches, and muscle pain. It did not control my blood sugar either. I never want to feel like that again. But, on the other hand, my husband is able to take it with no side effects, and it keeps his blood sugar between 90 and 130."

• Anonymous
• September 27, 2011

For Polycystic Ovary Syndrome "This medicine has definitely improved my quality of life. Within the first 2 weeks of starting metformin, I lost 8 pounds (where before I struggled to lose weight). Now I am in a healthy BMI for my height group. I experienced no nausea while taking this medicine (I took it in the middle of a meal). I did experience some intestinal side effects (gas/diarrhea) for the first week, and in the first week, I increased my dose."

• Rob...
• April 16, 2014

For Type 2 Diabetes "Severe diarrhea, unable to do my job because of it."

• Cot...
• Taken for 1 to 2 years
• November 6, 2015

For Type 2 Diabetes "Seems diarrhea is the main culprit with this med. Been taking it for 20 months so far, as far as control of diabetes, it does not seem to have much effect on blood sugar."

• san...
• April 7, 2016

For Type 2 Diabetes "Diarrhea so bad I lost control at work 3 times and had to go home. Never again. I don't care if I die from diabetes."

• Anonymous
• March 20, 2012

For Type 2 Diabetes "Made me very sick, headache, constant diarrhea, very bad head and chest cold, lower right leg started to swell."

• bla...
• May 7, 2009

For Polycystic Ovary Syndrome "It works great, but the downfall of Metformin is it causes you to have diarrhea, but it controls my insulin resistance."